Comparing PP_2704 FitnessBrowser__Putida:PP_2704 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 11 hits to proteins with known functional sites (download)
P54955 N-acetylcysteine deacetylase; S-(2-succino)cysteine metabolism operon protein P; EC 3.5.1.- from Bacillus subtilis (strain 168)
36% identity, 87% coverage: 19:362/394 of query aligns to 10:350/380 of P54955
O04373 IAA-amino acid hydrolase ILR1-like 4; jasmonoyl-L-amino acid hydrolase; EC 3.5.1.-; EC 3.5.1.127 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
32% identity, 96% coverage: 16:393/394 of query aligns to 45:423/440 of O04373
P54968 IAA-amino acid hydrolase ILR1; EC 3.5.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
32% identity, 99% coverage: 2:393/394 of query aligns to 38:427/442 of P54968
4ewtA The crystal structure of a putative aminohydrolase from methicillin resistant staphylococcus aureus (see paper)
30% identity, 96% coverage: 18:394/394 of query aligns to 15:389/389 of 4ewtA
6slfA Nalpha-acylglutamine aminoacylase from corynebacterium sp.Releasing human axilla odorants co-crystallised with high affinity inhibitor (see paper)
32% identity, 85% coverage: 12:346/394 of query aligns to 15:347/398 of 6slfA
Sites not aligning to the query:
3ramA Crystal structure of hmra (see paper)
23% identity, 68% coverage: 19:285/394 of query aligns to 18:265/391 of 3ramA
Sites not aligning to the query:
4pqaA Crystal structure of succinyl-diaminopimelate desuccinylase from neisseria meningitidis mc58 in complex with the inhibitor captopril (see paper)
23% identity, 70% coverage: 22:297/394 of query aligns to 8:288/375 of 4pqaA
Sites not aligning to the query:
4o23A Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from neisseria meningitidis mc58 (see paper)
23% identity, 70% coverage: 22:297/394 of query aligns to 8:288/376 of 4o23A
5vo3A Crystal structure of dape in complex with the products (succinic acid and diaminopimelic acid) (see paper)
22% identity, 72% coverage: 12:294/394 of query aligns to 2:293/380 of 5vo3A
Sites not aligning to the query:
P44514 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 3 papers)
22% identity, 71% coverage: 17:294/394 of query aligns to 3:289/377 of P44514
Sites not aligning to the query:
7lgpB Dape enzyme from shigella flexneri
24% identity, 69% coverage: 20:291/394 of query aligns to 8:287/377 of 7lgpB
>PP_2704 FitnessBrowser__Putida:PP_2704
MGILQSNQTPGSAAELDEFVMLRRQIHAAPEIGGDTPDTSALVADKLQALGYEVHRNVGG
HGVVGVLKVGDSPRSIGLRADMDALPMGEKNAFAHASKIPGRMHACGHDGHTAILLAAAA
QLAATRQFNGTLNVIFQPDEEGLAGAKAMIDDGLFERFPCDSVYALHNMPGLPVGTCVVQ
AGPTMASSERVSIRITGKGGHGAMPELSVDPVMALNSLISGIQTIKSRNLSVEDYAVISI
GMIQAGTVYNIIPDEACMLLSVRTDTAQTQQKINSRIDALAKGHAESYGVEIDVQFTQLA
PALCNSDHESTLLRDSLRPLFADGALLDKMPKKVMGTEDFAYMLQARPGCYFMLGNGTGE
FHGCSVHNPHYDFNDALVKIGADCWVKWVQDYLR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory