Comparing Pf1N1B4_180 FitnessBrowser__pseudo1_N1B4:Pf1N1B4_180 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 12 hits to proteins with known functional sites (download)
A0A0H2VG78 Glucose transporter GlcP; Glucose/H(+) symporter from Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) (see paper)
26% identity, 81% coverage: 71:440/459 of query aligns to 49:434/446 of A0A0H2VG78
Sites not aligning to the query:
Q8NLB7 Gentisate transporter from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
27% identity, 44% coverage: 36:236/459 of query aligns to 56:233/444 of Q8NLB7
Sites not aligning to the query:
Q9Y7Q9 Probable metabolite transporter C2H8.02 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
27% identity, 35% coverage: 71:230/459 of query aligns to 90:256/583 of Q9Y7Q9
Sites not aligning to the query:
P36035 Carboxylic acid transporter protein homolog from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
24% identity, 79% coverage: 77:437/459 of query aligns to 188:564/616 of P36035
Sites not aligning to the query:
P0AGF4 D-xylose-proton symporter; D-xylose transporter from Escherichia coli (strain K12) (see paper)
22% identity, 70% coverage: 62:381/459 of query aligns to 54:411/491 of P0AGF4
Sites not aligning to the query:
4gc0A The structure of the mfs (major facilitator superfamily) proton:xylose symporter xyle bound to 6-bromo-6-deoxy-d-glucose (see paper)
22% identity, 70% coverage: 62:381/459 of query aligns to 50:407/475 of 4gc0A
4gbzA The structure of the mfs (major facilitator superfamily) proton:xylose symporter xyle bound to d-glucose (see paper)
22% identity, 70% coverage: 62:381/459 of query aligns to 50:407/475 of 4gbzA
4gbyA The structure of the mfs (major facilitator superfamily) proton:xylose symporter xyle bound to d-xylose (see paper)
22% identity, 70% coverage: 62:381/459 of query aligns to 50:407/475 of 4gbyA
P25297 Inorganic phosphate transporter PHO84 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
24% identity, 82% coverage: 72:449/459 of query aligns to 110:564/587 of P25297
Sites not aligning to the query:
Q9VCA2 Organic cation transporter protein from Drosophila melanogaster (Fruit fly) (see paper)
26% identity, 69% coverage: 75:389/459 of query aligns to 139:468/548 of Q9VCA2
Sites not aligning to the query:
Q9R0W2 Solute carrier family 22 member 2; Organic cation transporter 2; rOCT2 from Rattus norvegicus (Rat) (see paper)
30% identity, 24% coverage: 79:187/459 of query aligns to 162:262/555 of Q9R0W2
Sites not aligning to the query:
Q8MJI6 Solute carrier family 22 member 2; Organic cation transporter 2 from Oryctolagus cuniculus (Rabbit) (see paper)
31% identity, 21% coverage: 79:176/459 of query aligns to 161:250/554 of Q8MJI6
Sites not aligning to the query:
>Pf1N1B4_180 FitnessBrowser__pseudo1_N1B4:Pf1N1B4_180
MSDLSPVEKSGAPPEVAISMKKVAVASVIGTTVEWYDLFVFATASALVFNKVFFPDFDPL
IGTLLAFGTFASAYLARIVGAALFGHFGDRLGRKSMLLVSLLTMGAATFAIGLLPNYAAI
GIWAPILLLLLRVIQGLALGGEWGGAVLMAVEHAPANKRGLYGSWVQIGVPAGTMIANLA
FLVIAAWLSPEDLLAWGWRIPFLASVLLIAVGLYIRLNISETPAFNKVKEAEVQVKMPLA
EVFRKYWKQVVLGGIATMSTGASFNIIVAFGLTYGTQNLGFSRSVMLGVVLLSCAWCIVM
LPVFGALSDRYGRKPIIVAGIVAEALVAFPMFWLMDTKELSLVIFGYLLLMTAFAANYGP
IATFLAELFGTRVRYSGLSISYMLSGLLGSAATPIVTTALLAATGKGSSVAWYMIGAAFI
SLVALLLLTETFKRDISEIQTAVPAADPALGKPIKSAAA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory