Comparing Pf1N1B4_3710 FitnessBrowser__pseudo1_N1B4:Pf1N1B4_3710 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P97084 Threonine-phosphate decarboxylase; L-threonine-O-3-phosphate decarboxylase; EC 4.1.1.81 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
27% identity, 71% coverage: 4:238/330 of query aligns to 8:263/364 of P97084
Sites not aligning to the query:
1lc7A Crystal structure of l-threonine-o-3-phosphate decarboxylase from s. Enterica complexed with a substrate (see paper)
26% identity, 71% coverage: 4:238/330 of query aligns to 5:260/358 of 1lc7A
Sites not aligning to the query:
1lkcA Crystal structure of l-threonine-o-3-phosphate decarboxylase from salmonella enterica (see paper)
26% identity, 71% coverage: 4:238/330 of query aligns to 1:256/355 of 1lkcA
Sites not aligning to the query:
1lc8A Crystal structure of l-threonine-o-3-phosphate decarboxylase from s. Enterica complexed with its reaction intermediate (see paper)
26% identity, 71% coverage: 4:238/330 of query aligns to 2:257/356 of 1lc8A
Sites not aligning to the query:
7szpA Crystal structure of histidinol-phosphate aminotransferase from klebsiella pneumoniae subsp. Pneumoniae (strain hs11286)
29% identity, 65% coverage: 32:246/330 of query aligns to 53:267/353 of 7szpA
1geyA Crystal structure of histidinol-phosphate aminotransferase complexed with n-(5'-phosphopyridoxyl)-l-glutamate (see paper)
34% identity, 49% coverage: 66:227/330 of query aligns to 61:233/335 of 1geyA
Sites not aligning to the query:
1fg7A Crystal structure of l-histidinol phosphate aminotransferase with pyridoxal-5'-phosphate (see paper)
34% identity, 49% coverage: 66:226/330 of query aligns to 75:246/354 of 1fg7A
1fg3A Crystal structure of l-histidinol phosphate aminotransferase complexed with l-histidinol (see paper)
34% identity, 49% coverage: 66:226/330 of query aligns to 75:246/354 of 1fg3A
Sites not aligning to the query:
P0DV65 L-serine phosphate decarboxylase; CobD homolog SMUL_1544; SmCobD; L-serine O-phosphate decarboxylase; L-Ser-P decarboxylase; Norcobamide biosynthesis protein SMUL_1544; Threonine phosphate decarboxylase-like enzyme; EC 4.1.1.- from Sulfurospirillum multivorans (strain DM 12446 / JCM 15788 / NBRC 109480) (see paper)
27% identity, 50% coverage: 72:235/330 of query aligns to 106:282/392 of P0DV65
Sites not aligning to the query:
3ly1D Crystal structure of putative histidinol-phosphate aminotransferase (yp_050345.1) from erwinia carotovora atroseptica scri1043 at 1.80 a resolution
26% identity, 58% coverage: 127:319/330 of query aligns to 144:331/354 of 3ly1D
Sites not aligning to the query:
2f8jA Crystal structure of histidinol-phosphate aminotransferase (ec 2.6.1.9) (imidazole acetol-phosphate transferase) (tm1040) from thermotoga maritima at 2.40 a resolution
24% identity, 55% coverage: 126:307/330 of query aligns to 141:320/335 of 2f8jA
Sites not aligning to the query:
1uu1A Complex of histidinol-phosphate aminotransferase (hisc) from thermotoga maritima (apo-form) (see paper)
24% identity, 55% coverage: 126:307/330 of query aligns to 135:314/329 of 1uu1A
Sites not aligning to the query:
1h1cA Histidinol-phosphate aminotransferase (hisc) from thermotoga maritima (see paper)
24% identity, 55% coverage: 126:307/330 of query aligns to 135:314/329 of 1h1cA
Sites not aligning to the query:
1uu0A Histidinol-phosphate aminotransferase (hisc) from thermotoga maritima (apo-form) (see paper)
24% identity, 55% coverage: 126:307/330 of query aligns to 134:313/328 of 1uu0A
Sites not aligning to the query:
Q9X0D0 Histidinol-phosphate aminotransferase; Imidazole acetol-phosphate transaminase; EC 2.6.1.9 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
24% identity, 55% coverage: 126:307/330 of query aligns to 140:319/335 of Q9X0D0
4r8dA Crystal structure of rv1600 encoded aminotransferase in complex with plp-mes from mycobacterium tuberculosis
27% identity, 42% coverage: 126:265/330 of query aligns to 163:301/369 of 4r8dA
Sites not aligning to the query:
4m2mA Crystal structure of plp-dependent cyclase orfr in complex with plp-l- arg (see paper)
29% identity, 57% coverage: 26:212/330 of query aligns to 26:240/380 of 4m2mA
Sites not aligning to the query:
4m2jA Crystal structure of plp-dependent cyclase orfr in complex with au (see paper)
29% identity, 57% coverage: 26:212/330 of query aligns to 30:244/382 of 4m2jA
1b5oA Thermus thermophilus aspartate aminotransferase single mutant 1 (see paper)
30% identity, 59% coverage: 67:260/330 of query aligns to 95:305/382 of 1b5oA
1gc4A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with aspartate (see paper)
30% identity, 59% coverage: 67:260/330 of query aligns to 95:305/382 of 1gc4A
Sites not aligning to the query:
>Pf1N1B4_3710 FitnessBrowser__pseudo1_N1B4:Pf1N1B4_3710
MLEHGGRLRKAALEYGIAEADWLDLSSGLAPWPFPVPDIPLRAWARLPETDDGLEQAACD
YYGAAQVLPVAGSQMAIQLLPRLRRAGKVGVLSPCYAEHAEAWRRNGYIVREVLESEVDF
FLDSLDVLVVVNPNNPTGLSLTPARLLDWHARLAQRGGWLVVDEAFMDNTPHLSLAPFAN
QIGLIVLRSFGKFFGLAGVRLGFVLAERKLLKLLAEQVGPWAVSGPTRVLGQACLTDTDG
HTRQRIRTDEAGERLALLLEQYGFKPQGGCALFQWLITECAEALHEFMARRGILLRLFTH
NSSVRFGLPADEADWLRLEQALEAYVKEAQ
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory