SitesBLAST – Find functional sites

 

SitesBLAST

Comparing Pf1N1B4_4068 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 3 hits to proteins with known functional sites (download)

P0AB18 Sulfurtransferase TusE; tRNA 2-thiouridine synthesizing protein E; EC 2.8.1.- from Escherichia coli (strain K12) (see paper)
44% identity, 94% coverage: 4:83/85 of query aligns to 2:81/109 of P0AB18

query
sites
P0AB18
L
 
L
T
 
I
V
 
F
G
 
E
A
 
G
R
 
K
A
 
E
I
 
I
E
 
E
L
 
T
D
 
D
K
 
T
D
 
E
G
 
G
F
 
Y
L
 
L
V
 
K
E
 
E
L
 
S
S
 
S
D
 
Q
W
 
W
S
 
S
A
 
E
E
 
P
V
 
L
A
 
A
A
 
V
A
 
V
L
 
I
A
 
A
A
 
E
A
 
N
E
 
E
D
 
G
I
 
I
E
 
S
L
 
L
S
 
S
P
 
P
E
 
E
H
 
H
W
 
W
E
 
E
I
 
V
L
 
V
E
 
R
L
 
F
L
 
V
R
 
R
S
 
D
F
 
F
Y
 
Y
D
 
L
E
 
E
F
 
F
Q
 
N
L
 
T
S
 
S
P
 
P
A
 
A
T
 
I
R
 
R
P
 
M
L
 
L
I
 
V
K
 
K
Y
 
A
T
 
M
A
 
A
L
 
N
K
 
K
L
 
F
G
 
G
P
 
E
T
 
E
R
 
K
A
 
G
T
 
N
A
 
S

Sites not aligning to the query:

2xsjC Structure of desulforubidin from desulfomicrobium norvegicum (see paper)
36% identity, 81% coverage: 8:76/85 of query aligns to 7:76/104 of 2xsjC

query
sites
2xsjC
A
 
G
R
 
K
A
 
S
I
 
F
E
 
E
L
 
I
D
 
D
K
 
E
D
 
D
G
 
G
F
 
F
L
 
L
V
 
L
E
 
K
L
 
F
S
 
E
D
 
D
W
 
W
S
 
G
A
 
P
E
 
E
V
 
W
A
 
A
A
 
E
A
 
Y
L
 
V
A
 
K
A
 
E
A
 
S
E
 
E
D
 
G
I
 
I
-
 
S
E
 
E
L
 
I
S
 
T
P
 
E
E
 
A
H
 
H
W
 
Q
E
 
Q
I
 
I
L
 
L
E
 
D
L
 
F
L
 
L
R
 
Q
S
 
D
F
 
Y
Y
 
Y
D
 
K
E
 
K
F
 
N
Q
 
G
L
 
I
S
 
A
P
 
P
A
 
M
T
 
V
R
 
R
P
 
I
L
 
L
I
 
S
K
 
K
Y
 
S
T
 
T
A
 
G
L
 
Y
K
 
K
L
 
L

Sites not aligning to the query:

3or2C Crystal structure of dissimilatory sulfite reductase ii (dsrii)
34% identity, 81% coverage: 8:76/85 of query aligns to 7:76/104 of 3or2C

query
sites
3or2C
A
 
G
R
 
S
A
 
A
I
 
F
E
 
E
L
 
V
D
 
D
K
 
E
D
 
D
G
 
G
F
 
F
L
 
L
V
 
N
E
 
A
L
 
F
S
 
D
D
 
D
W
 
W
S
 
C
A
 
P
E
 
E
V
 
W
A
 
V
A
 
K
A
 
Y
L
 
A
A
 
K
A
 
G
A
 
S
E
 
E
D
 
G
I
 
I
E
 
G
L
 
A
-
 
G
S
 
S
P
 
A
E
 
D
H
 
H
W
 
Q
E
 
K
I
 
I
L
 
I
E
 
D
L
 
F
L
 
L
R
 
Q
S
 
D
F
 
Y
Y
 
Y
D
 
K
E
 
A
F
 
N
Q
 
G
L
 
I
S
 
A
P
 
P
A
 
M
T
 
V
R
 
R
P
 
I
L
 
L
I
 
S
K
 
K
Y
 
V
T
 
T
A
 
G
L
 
F
K
 
K
L
 
L

Sites not aligning to the query:

Query Sequence

>Pf1N1B4_4068
MKSLTVGARAIELDKDGFLVELSDWSAEVAAALAAAEDIELSPEHWEILELLRSFYDEFQ
LSPATRPLIKYTALKLGPTRATACT

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory