Comparing Pf1N1B4_4430 FitnessBrowser__pseudo1_N1B4:Pf1N1B4_4430 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
1yt8A Crystal structure of thiosulfate sulfurtransferase from pseudomonas aeruginosa
44% identity, 54% coverage: 24:515/919 of query aligns to 23:516/525 of 1yt8A
P06721 Cystathionine beta-lyase MetC; CBL; CL; Beta-cystathionase MetC; Cysteine desulfhydrase MetC; CD; Cysteine lyase MetC; Cysteine-S-conjugate beta-lyase MetC; EC 4.4.1.13; EC 4.4.1.28 from Escherichia coli (strain K12) (see 2 papers)
41% identity, 42% coverage: 532:918/919 of query aligns to 3:395/395 of P06721
1cl1B Cystathionine beta-lyase (cbl) from escherichia coli (see paper)
41% identity, 42% coverage: 534:918/919 of query aligns to 2:392/392 of 1cl1B
2gqnA Cystathionine beta-lyase (cbl) from escherichia coli in complex with n-hydrazinocarbonylmethyl-2-nitro-benzamide (see paper)
41% identity, 42% coverage: 534:918/919 of query aligns to 1:391/391 of 2gqnA
2fq6A Cystathionine beta-lyase (cbl) from escherichia coli in complex with n-hydrazinocarbonylmethyl-2-trifluoromethyl-benzamide (see paper)
41% identity, 42% coverage: 534:918/919 of query aligns to 1:391/391 of 2fq6A
1cl2A Cystathionine beta-lyase (cbl) from escherichia coli in complex with aminoethoxyvinylglycine (see paper)
41% identity, 42% coverage: 534:918/919 of query aligns to 1:391/391 of 1cl2A
4itxA P113s mutant of e. Coli cystathionine beta-lyase metc inhibited by reaction with l-ala-p (see paper)
41% identity, 42% coverage: 534:918/919 of query aligns to 1:391/391 of 4itxA
8sadA Crystal structure of cystathionine beta lyase from klebsiella aerogenes, plp/malonate complex (c2 form)
40% identity, 42% coverage: 532:918/919 of query aligns to 6:398/398 of 8sadA
8u99A Crystal structure of cystathionine beta lyase from klebsiella aerogenes (plp-serine adduct)
40% identity, 42% coverage: 537:918/919 of query aligns to 4:391/391 of 8u99A
8u98A Crystal structure of cystathionine beta lyase from klebsiella aerogenes (plp-glycine adduct)
40% identity, 42% coverage: 537:918/919 of query aligns to 4:391/391 of 8u98A
8sa9A Crystal structure of cystathionine beta lyase from klebsiella aerogenes, plp-oxamate adduct (c2 form)
40% identity, 42% coverage: 537:918/919 of query aligns to 4:391/391 of 8sa9A
8sabA Crystal structure of cystathionine beta lyase from klebsiella aerogenes, plp adduct with alanine (c2 form)
40% identity, 42% coverage: 537:918/919 of query aligns to 5:392/392 of 8sabA
4l0oH Structure determination of cystathionine gamma-synthase from helicobacter pylori
37% identity, 42% coverage: 534:915/919 of query aligns to 2:371/373 of 4l0oH
7d7oB Crystal structure of cystathionine gamma-lyase from bacillus cereus atcc 14579 (see paper)
33% identity, 42% coverage: 534:915/919 of query aligns to 2:377/377 of 7d7oB
8j6nA Crystal structure of cystathionine gamma-lyase in complex with compound 1 (see paper)
34% identity, 41% coverage: 537:917/919 of query aligns to 11:388/390 of 8j6nA
7ba4A Structure of cystathionine gamma-lyase from pseudomonas aeruginosa
38% identity, 35% coverage: 592:915/919 of query aligns to 41:372/377 of 7ba4A
7mcyH Crystal structure of staphylococcus aureus cystathionine gamma lyase, holoenzyme with bound nl3 (see paper)
31% identity, 41% coverage: 536:914/919 of query aligns to 4:377/380 of 7mcyH
Sites not aligning to the query:
7mcuH Crystal structure of staphylococcus aureus cystathionine gamma lyase, holoenzyme with bound nl2 (see paper)
31% identity, 41% coverage: 536:914/919 of query aligns to 4:377/380 of 7mcuH
Sites not aligning to the query:
7mctH Crystal structure of staphylococcus aureus cystathionine gamma lyase, holoenzyme with bound nl1 (see paper)
31% identity, 41% coverage: 536:914/919 of query aligns to 4:377/380 of 7mctH
Sites not aligning to the query:
7mcqA Crystal structure of staphylococcus aureus cystathionine gamma lyase, aoaa-bound enzyme in dimeric form (see paper)
31% identity, 41% coverage: 536:914/919 of query aligns to 4:377/380 of 7mcqA
>Pf1N1B4_4430 FitnessBrowser__pseudo1_N1B4:Pf1N1B4_4430
MNRTVTPGQLQQWLFDGQEIALFDVREHGQYGEAHLFHGVNLPYSRLELEVRRLAPNPQV
RLVIYDQNGGDVVARAAQRLQALGYGRVHILDGGADGWQAAGLQLFAGVHVPSKAFGELV
EEVSHTPHVTARQLAEWQARGESLVVLDGRPFDEYRKMTIPGSVCCPNGELGYRVHDLVP
DDSTPIVVNCAGRTRSIIGAQTLINLGLKNPVYALENGTQGWDLEDLQLEHGSTRRYADE
VSSKTLPLQRLAAAQLAERAGVKTVATAQVEQWAGEAERSLFLCDVRTAEEFAAGSLPGA
QHTPGGQLIQSTDLYIGVRQARVVLIDSDGVRAPIIASWLRQLGHEAYVLADGVSSGLAL
PAVETPAHEALPVITAQALSDALKDNAVALIDLRPSMTWRKGHIAGSRWSIRSLLATEVM
GEQRPLVLLADDPLLAAFATLELPNAQRTQTRLLDGGVEAWRAAGFALQEDANTPPDHQC
IDFLFFTHDRHSGNKDAARQYLAWEIGLLAQMSADEIASLKPLRAQSQATRDARIRTRLV
HSARTEKGSGGRAVNVPVTRLSTVLFDNLAQMRDARARRDSERVLSYGARGNPTAFALED
LVTELEGGYRTRLYGTGLAAVAQTFLAYLRPGDHVLITDAVYAPVRRLARELLEPFGIQV
SYFAPDGSGLQAQLQANTKMVYTEVPGSLLYELCDLPAIAALCKPRGILLAVDNTWGSGY
LYRPLTLGADISIMALTKYLCGHSDVVMGSVCTRQEVWQPLSSMSDTFGIAVSPDDAYLV
LRGARTLAPRLDVHERQALEIAQWLQAQPQVKRVFHPALPDHPHHALWRRDFNGSNGLLS
FELREADATYVERFIDALQVFGLGASWGGYESLVTVADTKDRNSAADRALNPVLRLHIGL
EDVDALIEDLQRGFAAAVD
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory