Comparing Pf1N1B4_4449 FitnessBrowser__pseudo1_N1B4:Pf1N1B4_4449 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 12 hits to proteins with known functional sites (download)
Q9Y7Q9 Probable metabolite transporter C2H8.02 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
26% identity, 41% coverage: 17:236/540 of query aligns to 35:260/583 of Q9Y7Q9
Sites not aligning to the query:
P36035 Carboxylic acid transporter protein homolog from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
30% identity, 29% coverage: 75:232/540 of query aligns to 187:331/616 of P36035
Sites not aligning to the query:
Q09852 Putative inorganic phosphate transporter C23D3.12 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
25% identity, 44% coverage: 16:250/540 of query aligns to 39:286/559 of Q09852
Sites not aligning to the query:
O42885 Putative inorganic phosphate transporter C8E4.01c from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
25% identity, 43% coverage: 15:248/540 of query aligns to 39:288/572 of O42885
Sites not aligning to the query:
Q8NLB7 Gentisate transporter from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
23% identity, 37% coverage: 32:229/540 of query aligns to 52:231/444 of Q8NLB7
Sites not aligning to the query:
Q12300 High glucose sensor RGT2; Low-affinity glucose receptor RGT2; Low-affinity transporter-like sensor RGT2; Restores glucose transport protein 2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
27% identity, 45% coverage: 78:321/540 of query aligns to 158:426/763 of Q12300
Sites not aligning to the query:
8fvzA Pipt y150a
24% identity, 56% coverage: 22:325/540 of query aligns to 4:311/433 of 8fvzA
Sites not aligning to the query:
Q9Z2I6 Synaptic vesicle glycoprotein 2C; Synaptic vesicle protein 2C from Rattus norvegicus (Rat) (see 3 papers)
25% identity, 27% coverage: 79:224/540 of query aligns to 204:347/727 of Q9Z2I6
Sites not aligning to the query:
Q496J9 Synaptic vesicle glycoprotein 2C from Homo sapiens (Human) (see 4 papers)
25% identity, 27% coverage: 79:224/540 of query aligns to 204:347/727 of Q496J9
Sites not aligning to the query:
P25297 Inorganic phosphate transporter PHO84 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
20% identity, 60% coverage: 8:329/540 of query aligns to 50:433/587 of P25297
Sites not aligning to the query:
8bvtA Cryo-em structure of rat slc22a6 bound to probenecid (see paper)
24% identity, 46% coverage: 78:325/540 of query aligns to 138:390/508 of 8bvtA
Sites not aligning to the query:
8bvsA Cryo-em structure of rat slc22a6 bound to tenofovir (see paper)
24% identity, 46% coverage: 78:325/540 of query aligns to 129:381/502 of 8bvsA
>Pf1N1B4_4449 FitnessBrowser__pseudo1_N1B4:Pf1N1B4_4449
MSEHVQPMEAVRSAGTSQETQKVIFASSLGTVFEWYDFFLYGALAAVISKQFFAGVNDTT
AFIFALMAFAAGFIVRPFGALVFGRLGDMIGRKYTFLATIVLMGVATFCVGLLPTYASIG
IAAPIILVVLRMLQGLALGGEYGGAATYVAEHAPMGKRGFHTSWIQSTATLGLLLSLLVV
LGCRYFTGDQFEVWGWRIPFLFSIVLLGISTWIRLSLHESPAFVKMKEEGKLCKSPLRDS
FGKWDNLKVVLIALFSINAGQAVTFYAAQFYVLFFLTQFLKMDPALANSLLIVSVIIGAP
FFIFFGWLSDKVGRKPVLMIGLLLATALYFPIFKTLAHYANPAIDQASRQAPITVLADPA
TCTFQFDPVGKAKFDSPCDKVKTFLVKQGLPYNSEAAPAGSAVQVSIGEVKIDGYDEAAL
RGAVTLAGYPSQADTQLINKPMIVALIVALIIISAMCYGPLAALMVELFPTRIRYTSMSL
PYHIGNGWFGGFLPTVSFALVVYTGDIFYGLWYPVVITGVSLVVGMMCLRETKDVDLDKN
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory