SitesBLAST
Comparing Pf1N1B4_5638 FitnessBrowser__pseudo1_N1B4:Pf1N1B4_5638 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4ebuA Crystal structure of a sugar kinase (target efi-502312) from oceanicola granulosus, with bound amp/adp crystal form i
41% identity, 95% coverage: 13:308/310 of query aligns to 16:304/306 of 4ebuA
- active site: A263 (= A267), A264 (= A268), G265 (= G269), D266 (= D270)
- binding adenosine-5'-diphosphate: S202 (≠ T206), K233 (= K237), G235 (= G239), P236 (≠ A240), V252 (≠ A256), V255 (= V259), T261 (= T265), A264 (= A268), G265 (= G269), F268 (= F272), A290 (≠ H294), A293 (= A297)
4eumA Crystal structure of a sugar kinase (target efi-502132) from oceanicola granulosus with bound amp, crystal form ii
41% identity, 89% coverage: 13:288/310 of query aligns to 16:279/294 of 4eumA
- active site: A259 (= A267), A260 (= A268), G261 (= G269), D262 (= D270)
- binding adenosine monophosphate: S198 (≠ T206), K229 (= K237), N230 (≠ R238), G231 (= G239), P232 (≠ A240), V248 (≠ A256), V251 (= V259), A260 (= A268), G261 (= G269), F264 (= F272)
Sites not aligning to the query:
Q53W83 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
36% identity, 85% coverage: 27:288/310 of query aligns to 23:268/309 of Q53W83
Sites not aligning to the query:
1v1aA 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound 2- keto-3-deoxygluconate and adp (see paper)
36% identity, 85% coverage: 27:288/310 of query aligns to 23:268/301 of 1v1aA
- active site: G248 (≠ A267), A249 (= A268), G250 (= G269), D251 (= D270)
- binding adenosine-5'-diphosphate: K219 (= K237), G221 (= G239), A222 (= A240), F239 (≠ Q257), V241 (= V259), A243 (≠ V262), A249 (= A268), G250 (= G269), F253 (= F272)
- binding 2-keto-3-deoxygluconate: G33 (= G37), G34 (= G38), A35 (≠ D39), N38 (= N42), Y89 (= Y97), Y103 (= Y111), R105 (= R113), I134 (= I145), R167 (= R179), G248 (≠ A267), D251 (= D270)
Sites not aligning to the query:
1v1bA 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound atp (see paper)
36% identity, 85% coverage: 27:288/310 of query aligns to 23:268/300 of 1v1bA
- active site: G248 (≠ A267), A249 (= A268), G250 (= G269), D251 (= D270)
- binding adenosine-5'-triphosphate: N165 (= N177), S193 (≠ T206), K219 (= K237), G221 (= G239), G224 (≠ A242), A238 (= A256), F239 (≠ Q257), V241 (= V259), P246 (≠ T265), V247 (≠ T266), G248 (≠ A267), A249 (= A268), G250 (= G269), D251 (= D270), F253 (= F272)
Sites not aligning to the query:
Q8ZKR2 Aminoimidazole riboside kinase; AIRs kinase; EC 2.7.1.223 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
26% identity, 85% coverage: 13:277/310 of query aligns to 6:259/319 of Q8ZKR2
- D16 (≠ E23) binding
- G31 (= G38) binding
- Y101 (= Y111) binding
- R162 (= R179) binding
- A180 (≠ L197) binding
- A181 (≠ P198) binding
- A183 (≠ I200) binding
- G213 (= G230) binding
- D246 (= D264) binding
- T248 (= T266) binding
- D252 (= D270) binding
Sites not aligning to the query:
- 287 binding
- 290 binding
- 292 binding
2varA Crystal structure of sulfolobus solfataricus 2-keto-3-deoxygluconate kinase complexed with 2-keto-3-deoxygluconate (see paper)
21% identity, 93% coverage: 17:305/310 of query aligns to 6:292/311 of 2varA
- active site: G254 (≠ A267), A255 (= A268), G256 (= G269), D257 (= D270)
- binding adenosine monophosphate: K225 (= K237), G227 (= G239), S228 (≠ A240), G230 (≠ A242), A231 (≠ C243), A244 (≠ S251), Y245 (≠ F252), V249 (≠ A256), A255 (= A268), G256 (= G269), M259 (≠ F272), I281 (≠ H294), S284 (≠ A297), I288 (= I301)
- binding phosphoaminophosphonic acid-adenylate ester: N163 (= N177), R165 (= R179), K225 (= K237), G227 (= G239), S228 (≠ A240), G230 (≠ A242), A231 (≠ C243), A244 (≠ S251), Y245 (≠ F252), V249 (≠ A256), T253 (= T266), G254 (≠ A267), A255 (= A268), G256 (= G269), D257 (= D270), M259 (≠ F272), I281 (≠ H294), S284 (≠ A297), I288 (= I301)
- binding 3-deoxy-alpha-D-erythro-hex-2-ulofuranosonic acid: L10 (≠ M21), A32 (≠ G37), G33 (= G38), S34 (≠ D39), N37 (= N42), Y89 (= Y97), L103 (≠ F109), Y105 (= Y111), R107 (= R113), I136 (= I145), R165 (= R179), T253 (= T266), G254 (≠ A267), D257 (= D270)
- binding 2-keto-3-deoxygluconate: L10 (≠ M21), G33 (= G38), S34 (≠ D39), N37 (= N42), Y89 (= Y97), L103 (≠ F109), Y105 (= Y111), R107 (= R113), I136 (= I145), R165 (= R179), T253 (= T266), G254 (≠ A267), D257 (= D270)
Sites not aligning to the query:
Q97U29 2-dehydro-3-deoxygluconokinase/2-dehydro-3-deoxygalactonokinase; 2-dehydro-3-deoxyglucono/galactono-kinase; 2-keto-3-deoxy-galactonokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; KDGal kinase; EC 2.7.1.178 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
21% identity, 93% coverage: 17:305/310 of query aligns to 7:293/313 of Q97U29
Sites not aligning to the query:
1tz3A Crystal structure of aminoimidazole riboside kinase complexed with aminoimidazole riboside (see paper)
26% identity, 85% coverage: 13:277/310 of query aligns to 2:248/299 of 1tz3A
- active site: C24 (≠ S35), F88 (= F109), G238 (≠ A267), A239 (= A268), G240 (= G269), D241 (= D270)
- binding 5-aminoimidazole ribonucleoside: D8 (≠ E19), S10 (≠ M21), D12 (≠ E23), G26 (= G37), G27 (= G38), A28 (≠ D39), L83 (≠ C98), F88 (= F109), Y90 (= Y111), R151 (= R179), M154 (≠ L182), D241 (= D270)
3iq0B Crystal structure of a putative ribokinase ii in complex with atp and mg+2 from e.Coli
26% identity, 72% coverage: 60:283/310 of query aligns to 55:268/308 of 3iq0B
- active site: G252 (≠ A267), A253 (= A268), G254 (= G269), D255 (= D270)
- binding adenosine-5'-triphosphate: N164 (= N177), S192 (≠ T206), K223 (= K237), R224 (= R238), G225 (= G239), N226 (≠ A240), G228 (≠ A242), Y243 (≠ Q257), V245 (= V259), E247 (≠ R261), A253 (= A268), G254 (= G269), F257 (= F272)
Sites not aligning to the query:
1tz6A Crystal structure of aminoimidazole riboside kinase from salmonella enterica complexed with aminoimidazole riboside and atp analog (see paper)
26% identity, 85% coverage: 13:277/310 of query aligns to 2:248/297 of 1tz6A
- active site: C24 (≠ S35), F88 (= F109), G238 (≠ A267), A239 (= A268), G240 (= G269), D241 (= D270)
- binding phosphomethylphosphonic acid adenylate ester: D147 (= D175), N149 (= N177), K176 (≠ L204), S178 (≠ T206), E181 (≠ D209), S209 (≠ K237), G211 (= G239), A212 (= A240), G214 (vs. gap), A228 (= A256), V231 (= V259), V233 (= V262), A239 (= A268), G240 (= G269), F243 (= F272)
- binding 5-aminoimidazole ribonucleoside: D8 (≠ E19), S10 (≠ M21), D12 (≠ E23), G26 (= G37), G27 (= G38), A28 (≠ D39), N31 (= N42), L83 (≠ C98), F88 (= F109), Y90 (= Y111), R151 (= R179), M154 (≠ L182), T237 (= T266), D241 (= D270)
Sites not aligning to the query:
5eynA Crystal structure of fructokinase from vibrio cholerae o395 in fructose, adp, beryllium trifluoride and calcium ion bound form
23% identity, 85% coverage: 13:277/310 of query aligns to 3:256/306 of 5eynA
- active site: G246 (≠ A267), A247 (= A268), G248 (= G269), D249 (= D270)
- binding adenosine-5'-diphosphate: H91 (≠ A104), T217 (≠ K237), G219 (= G239), A220 (= A240), G222 (≠ A242), A238 (≠ V258), V239 (= V259), P241 (≠ V262), T244 (= T265), G246 (≠ A267), A247 (= A268), G248 (= G269), F251 (= F272)
- binding beryllium trifluoride ion: N157 (= N177), R159 (= R179), T245 (= T266), G246 (≠ A267), A247 (= A268), G248 (= G269), D249 (= D270)
- binding beta-D-fructofuranose: D9 (≠ E19), V11 (≠ M21), D13 (≠ E23), G27 (= G37), G28 (= G38), A29 (≠ D39), N32 (= N42), V84 (≠ Y97), F96 (= F109), F98 (≠ Y111), I127 (= I145), N157 (= N177), R159 (= R179), G246 (≠ A267), D249 (= D270)
Sites not aligning to the query:
2dcnA Crystal structure of 2-keto-3-deoxygluconate kinase from sulfolobus tokodaii complexed with 2-keto-6-phosphogluconate (alpha-furanose form)
23% identity, 87% coverage: 13:283/310 of query aligns to 2:268/308 of 2dcnA
- active site: G252 (≠ A267), A253 (= A268), G254 (= G269), D255 (= D270)
- binding adenosine-5'-diphosphate: D193 (= D208), K223 (= K237), L224 (≠ R238), G225 (= G239), P226 (≠ A240), G228 (≠ A242), Y243 (≠ Q257), V247 (= V262), V250 (≠ T265), A253 (= A268), G254 (= G269), L257 (≠ F272)
- binding 6-O-phosphono-beta-D-psicofuranosonic acid: L10 (≠ M21), A32 (≠ G37), G33 (= G38), S34 (≠ D39), N37 (= N42), F89 (≠ Y97), Y105 (= Y111), R107 (= R113), I136 (= I145), R165 (= R179), T251 (= T266), G252 (≠ A267), A253 (= A268), G254 (= G269), D255 (= D270)
Sites not aligning to the query:
3lkiB Crystal structure of fructokinase with bound atp from xylella fastidiosa
26% identity, 72% coverage: 54:277/310 of query aligns to 43:260/322 of 3lkiB
- active site: A250 (= A267), A251 (= A268), G252 (= G269), D253 (= D270)
- binding adenosine-5'-triphosphate: R161 (= R179), K186 (≠ L204), T221 (≠ K237), D222 (≠ R238), A223 (≠ G239), A224 (= A240), V227 (≠ C243), T240 (≠ A256), F241 (≠ Q257), V243 (= V259), V245 (= V262), A250 (= A267), A251 (= A268), G252 (= G269), F255 (= F272)
Sites not aligning to the query:
3in1A Crystal structure of a putative ribokinase in complex with adp from e.Coli
24% identity, 89% coverage: 32:306/310 of query aligns to 34:294/312 of 3in1A