Comparing Pf6N2E2_1456 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_1456 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P04983 Ribose import ATP-binding protein RbsA; EC 7.5.2.7 from Escherichia coli (strain K12) (see paper)
44% identity, 97% coverage: 5:504/518 of query aligns to 4:492/501 of P04983
4u00A Crystal structure of ttha1159 in complex with adp (see paper)
29% identity, 42% coverage: 5:224/518 of query aligns to 2:214/241 of 4u00A
P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 3 papers)
33% identity, 45% coverage: 5:236/518 of query aligns to 1:233/343 of P30750
Sites not aligning to the query:
6cvlD Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
32% identity, 45% coverage: 4:236/518 of query aligns to 1:234/344 of 6cvlD
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form (see paper)
32% identity, 45% coverage: 4:236/518 of query aligns to 1:234/344 of 3tuzC
Sites not aligning to the query:
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form (see paper)
32% identity, 45% coverage: 4:236/518 of query aligns to 1:234/344 of 3tuiC
1g6hA Crystal structure of the adp conformation of mj1267, an atp-binding cassette of an abc transporter (see paper)
27% identity, 46% coverage: 5:244/518 of query aligns to 4:254/254 of 1g6hA
3c4jA Abc protein artp in complex with atp-gamma-s
29% identity, 42% coverage: 5:224/518 of query aligns to 3:216/242 of 3c4jA
3c41J Abc protein artp in complex with amp-pnp/mg2+
29% identity, 42% coverage: 5:224/518 of query aligns to 3:216/242 of 3c41J
2olkA Abc protein artp in complex with adp-beta-s
29% identity, 42% coverage: 5:224/518 of query aligns to 3:216/242 of 2olkA
2oljA Abc protein artp in complex with adp/mg2+
29% identity, 42% coverage: 5:224/518 of query aligns to 3:216/242 of 2oljA
1g9xB Characterization of the twinning structure of mj1267, an atp-binding cassette of an abc transporter (see paper)
27% identity, 46% coverage: 5:243/518 of query aligns to 4:253/253 of 1g9xB
4ymuJ Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
28% identity, 42% coverage: 5:221/518 of query aligns to 1:212/240 of 4ymuJ
4f4cA The crystal structure of the multi-drug transporter (see paper)
33% identity, 40% coverage: 18:224/518 of query aligns to 1036:1238/1250 of 4f4cA
Sites not aligning to the query:
7z18I E. Coli c-p lyase bound to a phnk abc dimer and atp (see paper)
29% identity, 42% coverage: 5:222/518 of query aligns to 3:221/250 of 7z18I
7z15I E. Coli c-p lyase bound to a phnk/phnl dual abc dimer and adp + pi (see paper)
29% identity, 42% coverage: 5:222/518 of query aligns to 3:221/253 of 7z15I
1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
28% identity, 43% coverage: 8:232/518 of query aligns to 6:228/353 of 1oxvD
1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
28% identity, 43% coverage: 8:232/518 of query aligns to 6:228/353 of 1oxvA
1oxuA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
28% identity, 43% coverage: 8:232/518 of query aligns to 6:228/353 of 1oxuA
7z16I E. Coli c-p lyase bound to phnk/phnl dual abc dimer with amppnp and phnk e171q mutation (see paper)
28% identity, 42% coverage: 5:222/518 of query aligns to 3:221/250 of 7z16I
>Pf6N2E2_1456 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_1456
MSDYLLQMNGIVKTFGGVKALNGIDIKVRPGECVGLCGENGAGKSTLMKVLSAVYPYGTW
DGEILWDGQPLKAQSISETEAAGIVIIHQELTLVPDLSVAENIFMGHELTLPGGRMNYPA
MIHRAEALMRELKVPDMNVSLPVSQYGGGYQQLVEIAKALNKQARLLILDEPSSALTRSE
IEVLLDIIRDLKAKGVACVYISHKLDEVAAVCDTISVIRDGKHIATTAMADMSIPKIITQ
MVGREMSNLYPTEPHDVGEVIFEARHFTCYDVDNPRRKRVDDISFVLKRGEILGIAGLVG
AGRTELVSALFGAYPGRYEGEVWLNGQQIDTRTPLKSIRAGLCMVPEDRKRQGIIPDLGV
GQNITLAVLDNYSKLTRIDAEAELGSIDKEISRMHLKTASPFLPITSLSGGNQQKAVLAK
MLLTKPRVLILDEPTRGVDVGAKYEIYKLMGALAAEGVSIIMVSSELAEVLGVSDRVLVI
GDGQLRGDFINHELTQEQVLAAALSHPDGHNNNDRKSA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory