Comparing Pf6N2E2_1531 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_1531 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4yslA Crystal structure of sdoa from pseudomonas putida in complex with glutathione (see paper)
65% identity, 98% coverage: 6:292/292 of query aligns to 8:294/294 of 4yslA
4yskA Crystal structure of apo-form sdoa from pseudomonas putida (see paper)
65% identity, 98% coverage: 6:292/292 of query aligns to 8:294/294 of 4yskA
4efzA Crystal structure of a hypothetical metallo-beta-lactamase from burkholderia pseudomallei
63% identity, 98% coverage: 7:292/292 of query aligns to 7:295/295 of 4efzA
4ysbA Crystal structure of ethe1 from myxococcus xanthus (see paper)
33% identity, 90% coverage: 10:273/292 of query aligns to 6:225/225 of 4ysbA
5ve5A Crystal structure of persulfide dioxygenase rhodanese fusion protein with rhodanese domain inactivating mutation (c314s) from burkholderia phytofirmans in complex with glutathione (see paper)
32% identity, 92% coverage: 10:278/292 of query aligns to 9:236/350 of 5ve5A
4chlB Human ethylmalonic encephalopathy protein 1 (hethe1) (see paper)
31% identity, 90% coverage: 10:272/292 of query aligns to 12:232/237 of 4chlB
O95571 Persulfide dioxygenase ETHE1, mitochondrial; Ethylmalonic encephalopathy protein 1; Hepatoma subtracted clone one protein; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Homo sapiens (Human) (see 4 papers)
31% identity, 90% coverage: 10:272/292 of query aligns to 28:248/254 of O95571
Sites not aligning to the query:
Q9C8L4 Persulfide dioxygenase ETHE1 homolog, mitochondrial; Glyoxalase II; Glx II; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
30% identity, 90% coverage: 10:272/292 of query aligns to 57:285/294 of Q9C8L4
2gcuA X-ray structure of gene product from arabidopsis thaliana at1g53580 (see paper)
30% identity, 90% coverage: 10:272/292 of query aligns to 8:236/244 of 2gcuA
O24496 Hydroxyacylglutathione hydrolase cytoplasmic; Glyoxalase II; Glx II; EC 3.1.2.6 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
28% identity, 83% coverage: 19:260/292 of query aligns to 14:212/258 of O24496
Sites not aligning to the query:
7ev5A Crystal structure of bleg-1 b3 metallo-beta-lactamase (see paper)
32% identity, 51% coverage: 62:210/292 of query aligns to 34:191/209 of 7ev5A
3tp9A Crystal structure of alicyclobacillus acidocaldarius protein with beta-lactamase and rhodanese domains
25% identity, 70% coverage: 6:210/292 of query aligns to 4:198/473 of 3tp9A
3r2uB 2.1 angstrom resolution crystal structure of metallo-beta-lactamase from staphylococcus aureus subsp. Aureus col
24% identity, 70% coverage: 6:210/292 of query aligns to 6:189/336 of 3r2uB
Sites not aligning to the query:
7l0bA Crystal structure of hydroxyacyl glutathione hydrolase (glob) from staphylococcus aureus, apoenzyme (see paper)
28% identity, 55% coverage: 50:210/292 of query aligns to 33:185/202 of 7l0bA
3r2uA 2.1 angstrom resolution crystal structure of metallo-beta-lactamase from staphylococcus aureus subsp. Aureus col
23% identity, 70% coverage: 6:210/292 of query aligns to 4:197/348 of 3r2uA
1qh5B Human glyoxalase ii with s-(n-hydroxy-n-bromophenylcarbamoyl) glutathione (see paper)
26% identity, 66% coverage: 20:212/292 of query aligns to 15:175/260 of 1qh5B
Sites not aligning to the query:
1qh5A Human glyoxalase ii with s-(n-hydroxy-n-bromophenylcarbamoyl) glutathione (see paper)
26% identity, 66% coverage: 20:212/292 of query aligns to 15:175/260 of 1qh5A
Sites not aligning to the query:
1qh3A Human glyoxalase ii with cacodylate and acetate ions present in the active site (see paper)
26% identity, 66% coverage: 20:212/292 of query aligns to 15:175/260 of 1qh3A
Sites not aligning to the query:
Q16775 Hydroxyacylglutathione hydrolase, mitochondrial; Glyoxalase II; Glx II; EC 3.1.2.6 from Homo sapiens (Human) (see paper)
26% identity, 66% coverage: 20:212/292 of query aligns to 63:223/308 of Q16775
Sites not aligning to the query:
2zwrB Crystal structure of ttha1623 from thermus thermophilus hb8 (see paper)
30% identity, 49% coverage: 68:210/292 of query aligns to 50:184/207 of 2zwrB
>Pf6N2E2_1531 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_1531
MTVKPYVEGFFDPETHTVSYLVLDKTTRQCALIDSVLDFDPKSGRTTTTSADKLMARVLE
LEAKVQWILETHVHADHLTAAPYLKEKLGGTIGIGSQIATVQEVFGTLFNTGGEMPRDGS
QFDHLFVNDESFTIGTLQCHALHTPGHTPACMTYVISDGQETAAFVGDTLFMPDYGTARC
DFPGGNAHTLFRSINKVLSLPANTLLYTCHDYQPGGREVQFSSTVAEQRADNVHVRNGIS
EEAFVAMRTQRDASLDMPTLILPSVQVNMRAGHFPEPESNGTCYLKIPLNRL
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory