Comparing Pf6N2E2_1647 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_1647 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 4 hits to proteins with known functional sites (download)
7cagA Mycobacterium smegmatis lpqy-sugabc complex in the catalytic intermediate state (see paper)
39% identity, 90% coverage: 23:310/321 of query aligns to 3:276/285 of 7cagA
P94529 Arabinooligosaccharides transport system permease protein AraP from Bacillus subtilis (strain 168) (see paper)
28% identity, 83% coverage: 26:293/321 of query aligns to 28:286/313 of P94529
P02916 Maltose/maltodextrin transport system permease protein MalF from Escherichia coli (strain K12) (see 4 papers)
29% identity, 68% coverage: 100:318/321 of query aligns to 284:514/514 of P02916
4ki0F Crystal structure of the maltose-binding protein/maltose transporter complex in an outward-facing conformation bound to maltohexaose (see paper)
29% identity, 65% coverage: 100:307/321 of query aligns to 269:488/490 of 4ki0F
>Pf6N2E2_1647 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_1647
MSVSTTLAPGDDEYLLNRETPVQRRRVRAAWLFLSPMLLCLALVAAWPLLRTFWFSLTDA
SLADTGDATFVGLSNYLFHSSAGWSGILVDPQWWNAVRNTLHFTVVSVGLEIVLGLMVAL
LLNVKFTGRALVRALILIPWAIPTIVSAKIWSWMLNDQFGIINHLMLGLGLIDAPLAWTA
DADLSMWAVIIVDVWKTVPFVTLLMLAALQMLPSDCYEAARVDGIHPVKVFWWVTLPLLM
PALLVAAIFRILDSLRVFDVIYVLTSNSSSTMSMSVYARQHLVEFQDVGYGSAASTLLFL
VVAVIAMAYLYLGRRQLEVRS
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory