Comparing Pf6N2E2_3281 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_3281 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
Q94JV5 Deaminated glutathione amidase, chloroplastic/cytosolic; dGSH amidase; Nitrilase-like protein 2; Protein nitrilase 1 homolog; AtNit1; Protein Nit1 homolog; EC 3.5.1.128 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
42% identity, 93% coverage: 3:268/287 of query aligns to 39:302/307 of Q94JV5
Sites not aligning to the query:
P47016 Deaminated glutathione amidase; dGSH amidase; Nitrilase homolog 1; EC 3.5.1.128 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
34% identity, 93% coverage: 3:269/287 of query aligns to 8:302/307 of P47016
4hg5A Structural insights into yeast nit2: wild-type yeast nit2 in complex with oxaloacetate (see paper)
34% identity, 93% coverage: 3:269/287 of query aligns to 5:299/304 of 4hg5A
4hg3A Structural insights into yeast nit2: wild-type yeast nit2 in complex with alpha-ketoglutarate (see paper)
34% identity, 93% coverage: 3:269/287 of query aligns to 5:299/304 of 4hg3A
4hgdA Structural insights into yeast nit2: c169s mutant of yeast nit2 in complex with an endogenous peptide-like ligand (see paper)
33% identity, 93% coverage: 3:269/287 of query aligns to 4:295/299 of 4hgdA
Q9NQR4 Omega-amidase NIT2; Nitrilase homolog 2; EC 3.5.1.3 from Homo sapiens (Human) (see 2 papers)
32% identity, 93% coverage: 3:269/287 of query aligns to 6:265/276 of Q9NQR4
P46011 Bifunctional nitrilase/nitrile hydratase NIT4; Cyanoalanine nitrilase; Nitrilase 4; EC 3.5.5.1; EC 3.5.5.4; EC 4.2.1.65 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
27% identity, 96% coverage: 13:287/287 of query aligns to 49:346/355 of P46011
6ypaB The c146a variant of an amidase from pyrococcus horikoshii with bound glutaramide
28% identity, 85% coverage: 1:243/287 of query aligns to 9:234/269 of 6ypaB
7ovgA The c146a variant of an amidase from pyrococcus horikoshii with bound acetamide (see paper)
28% identity, 85% coverage: 1:243/287 of query aligns to 3:228/263 of 7ovgA
3klcB Crystal structure of hyperthermophilic nitrilase (see paper)
29% identity, 88% coverage: 1:253/287 of query aligns to 1:237/261 of 3klcB
Sites not aligning to the query:
3klcA Crystal structure of hyperthermophilic nitrilase (see paper)
29% identity, 88% coverage: 1:253/287 of query aligns to 1:237/261 of 3klcA
Q9UYV8 Nitrilase; PaNit; EC 3.5.5.1 from Pyrococcus abyssi (strain GE5 / Orsay) (see paper)
28% identity, 85% coverage: 1:243/287 of query aligns to 2:227/262 of Q9UYV8
5h8iC Crystal structure of medicago truncatula n-carbamoylputrescine amidohydrolase (mtcpa) in complex with n-(dihydroxymethyl)putrescine (see paper)
23% identity, 93% coverage: 3:269/287 of query aligns to 11:284/301 of 5h8iC
5h8jB Crystal structure of medicago truncatula n-carbamoylputrescine amidohydrolase (mtcpa) in complex with cadaverine (see paper)
23% identity, 93% coverage: 3:269/287 of query aligns to 7:280/297 of 5h8jB
5h8lB Crystal structure of medicago truncatula n-carbamoylputrescine amidohydrolase (mtcpa) c158s mutant in complex with putrescine (see paper)
22% identity, 93% coverage: 3:269/287 of query aligns to 8:281/298 of 5h8lB
O25067 Aliphatic amidase; Acylamide amidohydrolase; EC 3.5.1.4 from Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) (see paper)
25% identity, 92% coverage: 10:272/287 of query aligns to 27:277/339 of O25067
Q44185 N-carbamoyl-D-amino acid hydrolase; D-N-alpha-carbamilase; EC 3.5.1.77 from Rhizobium radiobacter (Agrobacterium tumefaciens) (Agrobacterium radiobacter) (see paper)
26% identity, 77% coverage: 18:237/287 of query aligns to 25:260/304 of Q44185
Q9UBR1 Beta-ureidopropionase; BUP-1; Beta-alanine synthase; N-carbamoyl-beta-alanine amidohydrolase; EC 3.5.1.6 from Homo sapiens (Human) (see 4 papers)
24% identity, 70% coverage: 20:221/287 of query aligns to 99:297/384 of Q9UBR1
Sites not aligning to the query:
7slyA Vanin-1 complexed with compound 27 (see paper)
27% identity, 55% coverage: 4:162/287 of query aligns to 17:194/461 of 7slyA
Sites not aligning to the query:
7slxA Vanin-1 complexed with compound 11 (see paper)
27% identity, 55% coverage: 4:162/287 of query aligns to 17:194/461 of 7slxA
Sites not aligning to the query:
>Pf6N2E2_3281 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_3281
MSVAVIQMVSQSDVLANLARARALLEQAAAGGARLAVLPENFAAMGRRDIADIGRAEAFG
QGPILPWLKQVARDLKLWIVAGTLPLPPVDQPEARSHACSLLVDDQGQIVARYDKLHLFD
VDVADNRGRYRESDDYAYGANVVVADTPVGRVGLTVCYDLRFPELYSELRAAGAELITAP
SAFTAVTGAAHWEVLIRARAIETQCYMLAAAQGGVHPGPRETFGHAAIVDPWGHVLAQQD
QGEAVLLAERDSSEQASIRARMPVASHRRFFSQGASPRPVQDDEFKA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory