Comparing Pf6N2E2_3940 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_3940 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 5 hits to proteins with known functional sites (download)
A0QJI1 Phosphoserine phosphatase; PSP; PSPase; O-phosphoserine phosphohydrolase; EC 3.1.3.3 from Mycobacterium avium (strain 104) (see paper)
26% identity, 93% coverage: 2:203/218 of query aligns to 182:367/411 of A0QJI1
5jlpA Crystal structure of mycobacterium avium serb2 in complex with serine at act domain
26% identity, 93% coverage: 2:203/218 of query aligns to 178:363/396 of 5jlpA
Sites not aligning to the query:
8a21A Crystal structure of phosphoserine phosphatase serb from mycobacterium avium in complex with phenylimidazole (see paper)
26% identity, 93% coverage: 2:203/218 of query aligns to 178:363/396 of 8a21A
Sites not aligning to the query:
8a1zA Crystal structure of phosphoserine phosphatase serb from mycobacterium avium in complex with 1-(2,4-dichlorophenyl)-3-hydroxyurea (see paper)
26% identity, 93% coverage: 2:203/218 of query aligns to 178:363/396 of 8a1zA
O53289 Phosphoserine phosphatase SerB2; PSP; PSPase; O-phosphoserine phosphohydrolase; Protein-serine/threonine phosphatase; EC 3.1.3.3; EC 3.1.3.16 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
24% identity, 93% coverage: 2:203/218 of query aligns to 180:365/409 of O53289
Sites not aligning to the query:
>Pf6N2E2_3940 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_3940
MRLALFDLDNTLLGGDSDHAWGDYLCERGFLDAVTYKARNDAFYQDYLAGKLDNAEYLNF
CLEILGRTEMDVLAQWHLDYMRDCIEPIVLPQAIELLEKHRDAGDKLVIITATNRFVTGP
IAERLGVETLIATECEMIDGRYSGRSTDVPCFREGKVTRLNRWLEETGHSLDGSYFYSDS
MNDLALLEVVTHPVAVDPDPNLRAEAHKRGWPVISLRG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory