Comparing Pf6N2E2_4961 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_4961 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 5 hits to proteins with known functional sites (download)
4f4fA X-ray crystal structure of plp bound threonine synthase from brucella melitensis
43% identity, 90% coverage: 1:409/454 of query aligns to 2:415/464 of 4f4fA
1kl7A Crystal structure of threonine synthase from yeast (see paper)
35% identity, 85% coverage: 3:389/454 of query aligns to 7:428/509 of 1kl7A
Sites not aligning to the query:
Q42598 Threonine synthase; TS; EC 4.2.3.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
35% identity, 85% coverage: 1:385/454 of query aligns to 5:427/514 of Q42598
8g1yA Crystal structure of the threonine synthase from streptococcus pneumoniae in complex with pyridoxal 5-phosphate.
31% identity, 91% coverage: 1:413/454 of query aligns to 5:435/496 of 8g1yA
1vb3A Crystal structure of threonine synthase from escherichia coli
30% identity, 86% coverage: 1:389/454 of query aligns to 1:362/428 of 1vb3A
>Pf6N2E2_4961 FitnessBrowser__pseudo6_N2E2:Pf6N2E2_4961
MRYVSTRNSAVQVDFEKVVLSAIAEDGGLFVPVELPPFEPQDIANWSTLSYDELAYRVMR
PFVGEAIPEADFKRVLKEAGSQFSHRSLAPLHQVDRNEWVLELFHGPTRSSKDFAAQLQA
RLVQYFLRKRGRRAVVVGVTNGDTGLAAIEAFKHCDETDVVVIYPEAGVPQDQLQDLQAT
AHPRVHQVAVDGSFDDCQTLVTQLFRQHEAISFNSSNWVSVMAQLVFYFHAVLQLGGGQR
PIGFSVPAASFAEVYAGYIAQKMGLPITQMIVATNQNDALHQFFLKNHYSRLRASKTLSP
AMDLSIFSNLERFLWELYGHDDQAVSALMHTFETHGEMTIANEFWLQARMIIDSYAVSDE
QTLEEITSLHRDTGYVIDPHTATGVLAARLYRRSLVAPMVTLGEISPVKSAVLLDELGIH
IAARQRPVSEHGPAQIHRLQPDDLGALHQLLGAL
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory