Comparing Pf6N2E2_804 Fructokinase (EC 2.7.1.4) to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4wjmA Crystal structure of fructokinase from brucella abortus 2308 with bound amppnp
34% identity, 100% coverage: 1:311/312 of query aligns to 7:312/312 of 4wjmA
7fcaD Pfkb(mycobacterium marinum) (see paper)
35% identity, 96% coverage: 3:302/312 of query aligns to 5:281/282 of 7fcaD
5eynA Crystal structure of fructokinase from vibrio cholerae o395 in fructose, adp, beryllium trifluoride and calcium ion bound form
29% identity, 93% coverage: 4:294/312 of query aligns to 6:300/306 of 5eynA
5yggA Crystal structure of fructokinase double-mutant (t261c-h108c) from vibrio cholerae o395 in fructose, adp and potassium ion bound form (see paper)
30% identity, 88% coverage: 21:294/312 of query aligns to 20:304/310 of 5yggA
Sites not aligning to the query:
3gbuA Crystal structure of an uncharacterized sugar kinase ph1459 from pyrococcus horikoshii in complex with atp
29% identity, 98% coverage: 5:311/312 of query aligns to 5:292/302 of 3gbuA
3ih0A Crystal structure of an uncharacterized sugar kinase ph1459 from pyrococcus horikoshii in complex with amp-pnp
29% identity, 98% coverage: 5:311/312 of query aligns to 6:293/304 of 3ih0A
Q8ZKR2 Aminoimidazole riboside kinase; AIRs kinase; EC 2.7.1.223 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
28% identity, 94% coverage: 21:312/312 of query aligns to 19:304/319 of Q8ZKR2
Sites not aligning to the query:
1tz6A Crystal structure of aminoimidazole riboside kinase from salmonella enterica complexed with aminoimidazole riboside and atp analog (see paper)
28% identity, 94% coverage: 21:312/312 of query aligns to 15:293/297 of 1tz6A
Sites not aligning to the query:
1tz3A Crystal structure of aminoimidazole riboside kinase complexed with aminoimidazole riboside (see paper)
28% identity, 94% coverage: 21:312/312 of query aligns to 15:293/299 of 1tz3A
Sites not aligning to the query:
3lkiB Crystal structure of fructokinase with bound atp from xylella fastidiosa
29% identity, 96% coverage: 3:302/312 of query aligns to 6:302/322 of 3lkiB
3iq0B Crystal structure of a putative ribokinase ii in complex with atp and mg+2 from e.Coli
27% identity, 76% coverage: 33:269/312 of query aligns to 36:267/308 of 3iq0B
Sites not aligning to the query:
4xckA Vibrio cholerae o395 ribokinase complexed with adp, ribose and cesium ion. (see paper)
26% identity, 78% coverage: 26:267/312 of query aligns to 32:265/306 of 4xckA
Sites not aligning to the query:
8cqxA Ribokinase from t.Sp mutant a92g
27% identity, 92% coverage: 26:312/312 of query aligns to 30:295/300 of 8cqxA
Q53W83 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
29% identity, 74% coverage: 32:262/312 of query aligns to 33:259/309 of Q53W83
Sites not aligning to the query:
1v1bA 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound atp (see paper)
29% identity, 74% coverage: 32:262/312 of query aligns to 33:259/300 of 1v1bA
Sites not aligning to the query:
1v1aA 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound 2- keto-3-deoxygluconate and adp (see paper)
29% identity, 74% coverage: 32:262/312 of query aligns to 33:259/301 of 1v1aA
Sites not aligning to the query:
6znxC Ribokinase from thermus species
26% identity, 92% coverage: 26:312/312 of query aligns to 17:260/265 of 6znxC
2fv7A Crystal structure of human ribokinase
25% identity, 90% coverage: 32:311/312 of query aligns to 38:303/308 of 2fv7A
5c3yA Structure of human ribokinase crystallized with amppnp
25% identity, 90% coverage: 32:311/312 of query aligns to 38:303/306 of 5c3yA
5byfA Crystal structure of human ribokinase in complex with amp
25% identity, 90% coverage: 32:311/312 of query aligns to 40:305/313 of 5byfA
>Pf6N2E2_804 Fructokinase (EC 2.7.1.4)
MYLVCGEALFDFFSETEADGPASQVNYKAIAGGSPFNVAVGLRRLGVESALFTGLSTDYL
GRRLHQVLLNEGVSAQYLVDFDAPTTLAMVAVGANGSPHYSFRGEGCADRQLSLAHLPDL
GPEVRGLHFGSFSLVVQPIADTLLALMQRESGRRLISLDPNVRLNPQPDIELWRSRIATL
VQYADLIKVSDEDLDLLYPAKEPEAIIEGWLGNRCQLVFLTRGGQGATVFSRQHGSWSLP
SCPVKIADTVGAGDTFQAALIAWLTEQQLDSIEGLHTLTREQISAMLEFAIRAAALTCGK
TGPDLPYRHQLN
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory