Comparing PfGW456L13_1425 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_1425 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
Q88JU3 3-dehydroshikimate dehydratase; DSD; EC 4.2.1.118 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
82% identity, 100% coverage: 1:633/633 of query aligns to 1:635/635 of Q88JU3
5hmqD Xylose isomerase-like tim barrel/4-hydroxyphenylpyruvate dioxygenase fusion protein
82% identity, 99% coverage: 1:625/633 of query aligns to 3:624/624 of 5hmqD
7xntA Crystal structure of pfhppd-y13161 complex
34% identity, 54% coverage: 285:624/633 of query aligns to 3:341/341 of 7xntA
1cjxA Crystal structure of pseudomonas fluorescens hppd (see paper)
35% identity, 53% coverage: 296:628/633 of query aligns to 9:351/352 of 1cjxA
7x8eA Crystal structure of pfhppd-y13287 complex
35% identity, 54% coverage: 285:624/633 of query aligns to 2:337/341 of 7x8eA
7xntC Crystal structure of pfhppd-y13161 complex
35% identity, 52% coverage: 285:612/633 of query aligns to 2:313/320 of 7xntC
Sites not aligning to the query:
O52791 4-hydroxymandelate synthase; HMS; HmaS; 4-hydroxyphenylpyruvate dioxygenase II; EC 1.13.11.46 from Amycolatopsis orientalis (Nocardia orientalis) (see paper)
30% identity, 53% coverage: 297:630/633 of query aligns to 6:357/357 of O52791
2r5vA Hydroxymandelate synthase crystal structure (see paper)
30% identity, 52% coverage: 297:626/633 of query aligns to 5:346/346 of 2r5vA
1t47A Structure of fe2-hppd bound to ntbc (see paper)
27% identity, 47% coverage: 328:624/633 of query aligns to 44:360/362 of 1t47A
7yvvA Acmp1, r-4-hydroxymandelate synthase
27% identity, 45% coverage: 339:624/633 of query aligns to 48:334/335 of 7yvvA
Q02110 4-hydroxyphenylpyruvate dioxygenase; 4-hydroxyphenylpyruvic acid oxidase; 4HPPD; HPD; HPPDase; EC 1.13.11.27 from Sus scrofa (Pig) (see paper)
29% identity, 28% coverage: 435:612/633 of query aligns to 177:363/393 of Q02110
Sites not aligning to the query:
7x5wA Crystal structure of athppd-y18022 complex
28% identity, 42% coverage: 335:601/633 of query aligns to 73:350/381 of 7x5wA
Sites not aligning to the query:
8i0yA Crystal structure of athppd-y191713 complex
27% identity, 42% coverage: 335:601/633 of query aligns to 73:351/382 of 8i0yA
Sites not aligning to the query:
7x6nA Crystal structure of athppd-y191710 complex
27% identity, 42% coverage: 335:601/633 of query aligns to 73:351/382 of 7x6nA
Sites not aligning to the query:
3zgjB S221m v223f y359a mutant of 4-hydroxymandelate synthase from streptomyces coelicolor (see paper)
28% identity, 49% coverage: 316:624/633 of query aligns to 24:342/343 of 3zgjB
5yy6A Crystal structure of arabidopsis thaliana hppd truncated mutant complexed with benquitrione (see paper)
27% identity, 42% coverage: 335:601/633 of query aligns to 73:344/371 of 5yy6A
Sites not aligning to the query:
5ywgA Crystal structure of arabidopsis thaliana hppd complexed with mesotrione (see paper)
28% identity, 42% coverage: 334:601/633 of query aligns to 61:338/366 of 5ywgA
Sites not aligning to the query:
1tg5A Crystal structures of plant 4-hydroxyphenylpyruvate dioxygenases complexed with das645 (see paper)
28% identity, 43% coverage: 335:605/633 of query aligns to 73:351/371 of 1tg5A
Sites not aligning to the query:
5ywhA Crystal structure of arabidopsis thaliana hppd complexed with y13508
28% identity, 42% coverage: 334:601/633 of query aligns to 61:344/372 of 5ywhA
Sites not aligning to the query:
1sqdA Structural basis for inhibitor selectivity revealed by crystal structures of plant and mammalian 4-hydroxyphenylpyruvate dioxygenases (see paper)
28% identity, 42% coverage: 335:601/633 of query aligns to 73:347/373 of 1sqdA
>PfGW456L13_1425 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_1425
MQRSIATVSLSGTLPEKLEAIAAAGFDGVEIFENDLLYYDGSPREIKQMCADLGIAITLF
QPFRDFEGCRRDRLSRNLERAERKFDLMQELGTDLVLVCSNASAESIGDEQVLVDDLRLL
AEHAGARGLRIGYEALAWGRHVNTWQQVWNIVRQADHPSLGVLLDSFHTLSLKGDPSAIA
EIPGDKIFFVQMADAPILAMDVLEWSRHFRCFPGQGEFDLPGFLAPIIKSGYTGPLSLEI
FNDGFRAAPPRANAADGLRSLLYLEEKTRERLAQEAKPATNSEILFETPKASEYNGIEFL
EFAVDESLGAKLSHWLERLGFVKAGQHRSKSVSLMRQGDINLILNSEPYSFGHSFFEAHG
PSLCATAVRVKDSASALARAVAYKGQPYRGLVGPNELELAAVRAPDGSLIYLVDQDADVY
GTDFNLLADAPVSGGLKRIDHMAMALPADSLDSWVLFYKSLLDFEADDEVVLPDPYGLVK
SRALRSRDSSIRLPLNISENRNTAISHALSSYRGSGVHHIAFDCDDIFAQVSRAKEAGVP
LLDIPLNYYDDLAARFDFDDEFLSELAYYNVLYDRDAQGGELFHVYTEPFEGRFFFEIIQ
RKNGYAGYGAANVAVRLAAMAKSRSGALRQAKL
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory