Comparing PfGW456L13_1623 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_1623 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
2xf4A Crystal structure of salmonella enterica serovar typhimurium ycbl (see paper)
40% identity, 94% coverage: 12:212/213 of query aligns to 6:209/210 of 2xf4A
7ev5A Crystal structure of bleg-1 b3 metallo-beta-lactamase (see paper)
37% identity, 94% coverage: 13:213/213 of query aligns to 6:209/209 of 7ev5A
2zwrB Crystal structure of ttha1623 from thermus thermophilus hb8 (see paper)
38% identity, 95% coverage: 11:213/213 of query aligns to 3:202/207 of 2zwrB
2zziA Crystal structure of ttha1623 in a di-iron-bound form (see paper)
38% identity, 94% coverage: 11:211/213 of query aligns to 1:198/198 of 2zziA
7l0bA Crystal structure of hydroxyacyl glutathione hydrolase (glob) from staphylococcus aureus, apoenzyme (see paper)
36% identity, 86% coverage: 30:213/213 of query aligns to 23:202/202 of 7l0bA
4ysbA Crystal structure of ethe1 from myxococcus xanthus (see paper)
29% identity, 90% coverage: 23:213/213 of query aligns to 17:192/225 of 4ysbA
O95571 Persulfide dioxygenase ETHE1, mitochondrial; Ethylmalonic encephalopathy protein 1; Hepatoma subtracted clone one protein; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Homo sapiens (Human) (see 4 papers)
29% identity, 91% coverage: 2:195/213 of query aligns to 19:195/254 of O95571
Sites not aligning to the query:
4chlB Human ethylmalonic encephalopathy protein 1 (hethe1) (see paper)
28% identity, 90% coverage: 5:195/213 of query aligns to 6:179/237 of 4chlB
4efzA Crystal structure of a hypothetical metallo-beta-lactamase from burkholderia pseudomallei
30% identity, 79% coverage: 44:212/213 of query aligns to 54:239/295 of 4efzA
5ve5A Crystal structure of persulfide dioxygenase rhodanese fusion protein with rhodanese domain inactivating mutation (c314s) from burkholderia phytofirmans in complex with glutathione (see paper)
26% identity, 90% coverage: 23:213/213 of query aligns to 20:198/350 of 5ve5A
Sites not aligning to the query:
4yslA Crystal structure of sdoa from pseudomonas putida in complex with glutathione (see paper)
32% identity, 68% coverage: 44:187/213 of query aligns to 56:205/294 of 4yslA
Sites not aligning to the query:
4yskA Crystal structure of apo-form sdoa from pseudomonas putida (see paper)
32% identity, 68% coverage: 44:187/213 of query aligns to 56:205/294 of 4yskA
2gcuA X-ray structure of gene product from arabidopsis thaliana at1g53580 (see paper)
27% identity, 85% coverage: 30:209/213 of query aligns to 28:201/244 of 2gcuA
Q9C8L4 Persulfide dioxygenase ETHE1 homolog, mitochondrial; Glyoxalase II; Glx II; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
27% identity, 85% coverage: 30:209/213 of query aligns to 77:250/294 of Q9C8L4
3tp9A Crystal structure of alicyclobacillus acidocaldarius protein with beta-lactamase and rhodanese domains
27% identity, 88% coverage: 23:209/213 of query aligns to 19:212/473 of 3tp9A
Q9SID3 Hydroxyacylglutathione hydrolase 2, mitochondrial; Glyoxalase II; Glx II; EC 3.1.2.6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
27% identity, 81% coverage: 23:195/213 of query aligns to 86:239/324 of Q9SID3
2q42A Ensemble refinement of the protein crystal structure of glyoxalase ii from arabidopsis thaliana gene at2g31350 (see paper)
27% identity, 81% coverage: 23:195/213 of query aligns to 16:169/254 of 2q42A
6sg9FL uS3m (see paper)
40% identity, 39% coverage: 125:208/213 of query aligns to 209:294/320 of 6sg9FL
Sites not aligning to the query:
6n36A Beta-lactamase from chitinophaga pinensis
31% identity, 62% coverage: 12:144/213 of query aligns to 25:164/265 of 6n36A
Sites not aligning to the query:
3r2uB 2.1 angstrom resolution crystal structure of metallo-beta-lactamase from staphylococcus aureus subsp. Aureus col
26% identity, 94% coverage: 3:202/213 of query aligns to 1:196/336 of 3r2uB
Sites not aligning to the query:
>PfGW456L13_1623 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_1623
MSQQPTLIRETFPVGPLQCNCTIIGDPVTKKAIVVDPGGNHELILARLDALGLKVVSIIH
THAHLDHFLASGQLKEKTGATLHLHKEDQFLWDNLEMQCQMFGVPYTPVPSPDRWLADDE
ELACGCGVALHTPGHTPGSMSFWFSEAKLLIAGDTLFRRGVGRTDLWGGDQATIVRSIKQ
RLYTLDEDATVVTGHGPDTRLGDEMRENPFVRG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory