SitesBLAST

2cz2A Crystal structure of glutathione transferase zeta 1-1 (maleylacetoacetate isomerase) from mus musculus (form-1 crystal)
28% identity, 84% coverage: 6:181/210 of query aligns to 4:178/212 of 2cz2A

query
sites
2cz2A

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binding glutathione: S11 (= S13), S12 (= S14), C13 (≠ W15), R16 (= R18), L35 (= L34), Q42 (≠ D41), F43 (≠ T42), K54 (≠ G53), Q55 (≠ K54), V56 (= V55), Q68 (≠ D67), S69 (= S68), Q108 (≠ F107), N112 (≠ G111), L113 (vs. gap), S114 (≠ N112)

Q9WVL0 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Mus musculus (Mouse)
28% identity, 84% coverage: 6:181/210 of query aligns to 7:181/216 of Q9WVL0

query
sites
Q9WVL0

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Q45 (≠ D41) binding
V59 (= V55) binding
Q111 (≠ F107) binding

7dweA Crystal structure of a glutathione s-transferase sbgstu7 from salix babylonica in complex with glutathione
40% identity, 41% coverage: 10:96/210 of query aligns to 4:93/212 of 7dweA

query
sites
7dweA

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binding glutathione: F8 (≠ S14), S11 (vs. gap), F13 (vs. gap), L35 (≠ Q39), K38 (≠ T42), K51 (= K54), T52 (≠ V55), P53 (= P56), E64 (≠ D67), S65 (= S68)

8a0pA Crystal structure of poplar glutathione transferase u20 in complex with morin (see paper)
39% identity, 41% coverage: 10:96/210 of query aligns to 4:93/216 of 8a0pA

query
sites
8a0pA

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binding 2-[2,4-bis(oxidanyl)phenyl]-3,5,7-tris(oxidanyl)chromen-4-one: V10 (vs. gap), S11 (vs. gap), P12 (vs. gap), F13 (vs. gap)

Sites not aligning to the query:

binding 2-[2,4-bis(oxidanyl)phenyl]-3,5,7-tris(oxidanyl)chromen-4-one: 103, 106, 156, 157, 160, 161, 164, 207, 208

8a0rA Crystal structure of poplar glutathione transferase u20 in complex with pinocembrin (see paper)
39% identity, 41% coverage: 10:96/210 of query aligns to 3:92/215 of 8a0rA

query
sites
8a0rA

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binding pinocembrin: P11 (vs. gap), F12 (vs. gap)

Sites not aligning to the query:

binding pinocembrin: 102, 105, 155, 156, 159, 163, 206, 207

8a0qA Crystal structure of poplar glutathione transferase u20 in complex with baicalein (see paper)
39% identity, 41% coverage: 10:96/210 of query aligns to 3:92/215 of 8a0qA

query
sites
8a0qA

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binding 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one: S10 (vs. gap), P11 (vs. gap), F12 (vs. gap)

Sites not aligning to the query:

binding 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one: 105, 155, 159, 163, 206

8a0oA Crystal structure of poplar glutathione transferase u20 in complex with galangin (see paper)
39% identity, 41% coverage: 10:96/210 of query aligns to 3:92/215 of 8a0oA

query
sites
8a0oA

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binding galangin: V9 (vs. gap), S10 (vs. gap), P11 (vs. gap), F12 (vs. gap)

Sites not aligning to the query:

binding galangin: 102, 105, 155, 159, 160, 163, 206, 207

8a0iA Crystal structure of poplar glutathione transferase u20 in complex with glutathionylphenylacetophenone (see paper)
39% identity, 41% coverage: 10:96/210 of query aligns to 3:92/215 of 8a0iA

query
sites
8a0iA

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binding L-gamma-glutamyl-S-(2-biphenyl-4-yl-2-oxoethyl)-L-cysteinylglycine: S10 (vs. gap), P11 (vs. gap), F12 (vs. gap), L34 (≠ Q39), K37 (≠ T42), K50 (= K54), I51 (≠ V55), P52 (= P56), E63 (≠ D67), S64 (= S68)

Sites not aligning to the query:

binding L-gamma-glutamyl-S-(2-biphenyl-4-yl-2-oxoethyl)-L-cysteinylglycine: 105, 106, 109, 163, 207, 214

8a08A Crystal structure of poplar glutathione transferase u20 in complex with glutathione (see paper)
39% identity, 41% coverage: 10:96/210 of query aligns to 3:92/215 of 8a08A

query
sites
8a08A

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binding glutathione: S10 (vs. gap), F12 (vs. gap), L34 (≠ Q39), K37 (≠ T42), K50 (= K54), I51 (≠ V55), P52 (= P56), E63 (≠ D67), S64 (= S68)

O43708 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Homo sapiens (Human) (see 10 papers)
31% identity, 84% coverage: 6:181/210 of query aligns to 7:181/216 of O43708

query
sites
O43708

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I

I

A

I

E

E

Y

Y

L

L

A

E

E

E

Q
x
M

F

R

P

P

D

T

A

P

N

R

L

L

W

L

P

P

K

Q

D

D

T

P

A

K

R

R

A

A

Q

S

A
x
V

R

R

S

-

A

-

C

-

A

-

Q

-

M

M

H

I

S

S

G

D

F

L

F

I

A

A

M

-

R

G

G

G

N

I

M
x
Q

P

P

F

-

D

-

L

L

G

Q

H

N

D

L

A

S

A

V

L

L

S

K

P

Q

V

V

P

G

A

-

D

-

V

-

Q

-

A

-

D

-

I

-

E

E

R

E

M

M

S

Q

A

L

L

T

W

W

A

A

E

Q

-
x
N

-

A

-

I

-

T

C

C

R

G

V

F

A

N

A

A

T

L

E

E

-

Q

-

I

-

L

-

Q

-

S

-

T

S
x
A

G

G

P

I

Y

Y

L

C

F

V

G

G

-

D

R

E

I

V

T

T

L

M

A

A

D

D

A

L

F

C

F

L

A

V

P

P

I

Q

A

V

V

A

R

N

L

A

R

E

T

R

Y

F

R

K

V

V

K

D

L

L

S

T

K32 (≠ T31) to E: in allele GSTZ1*C; dbSNP:rs7975
R42 (≠ T42) to G: in allele GSTZ1*B and allele GSTZ1*C; dbSNP:rs7972
Q45 (≠ R45) binding
V59 (= V55) binding
M82 (≠ Q78) to T: in dbSNP:rs1046428
V99 (≠ A95) to M: in MAAID; decreased maleylacetoacetate isomerase activity
Q111 (≠ M113) binding
N133 (vs. gap) to H: in dbSNP:rs2234955
A150 (≠ S151) to V: in MAAID; decreased maleylacetoacetate isomerase activity

1fw1A Glutathione transferase zeta/maleylacetoacetate isomerase (see paper)
31% identity, 84% coverage: 6:181/210 of query aligns to 3:177/208 of 1fw1A

query
sites
1fw1A

I

I

I

L

G

Y

D

S

K

Y

L

F

H

R

S
|
S

W
x
C

S

S

L

W

R
|
R

G

V

A

R

L

I

A

A

L

L

D

A

L

L

A

K

G

G

A

I

S

D

Y

Y

T

K

E

T

E

V

L

P

I

I

K

N

L
|
L

N

I

Q

K

P

-

D

D

T

G

R

G

E

Q

R
x
Q

L

F

L

S

K

K

H

D

-

F

-

Q

-

A

-

L

S

N

P

P

T

M

G

K

K
x
Q

V
|
V

P

P

L

T

L

L

K

K

T

I

E

D

H

G

G

I

T

T

I

I

A

H

D
x
Q

S
|
S

L

L

A

A

I

I

A

I

E

E

Y

Y

L

L

A

E

E

E

Q

T

F

R

P

P

D

T

A

P

N

R

L

L

W

L

P

P

K

Q

D

D

T

P

A

K

R

R

A

A

Q

S

A

V

R

R

S

-

A

-

C

-

A

-

Q

-

M

M

H

I

S

S

G

D

F

L

F

I

A

A

M

-

R

G

G

G

N

I

M
x
Q

P

P

F

-

D

-

L

L

G
x
Q

H
x
N

D
x
L

A
x
S

A

V

L

L

S

K

P

Q

V

V

P

G

A

-

D

-

V

-

Q

-

A

-

D

-

I

-

E

E

R

E

M

M

S

Q

A

L

L

T

W

W

A

A

E

Q

-

N

-

A

-

I

-

T

C

C

R

G

V

F

A

N

A

A

T

L

E

E

-

Q

-

I

-

L

-

Q

-

S

-

T

S

A

G

G

P

I

Y

Y

L

C

F

V

G

G

-

D

R

E

I

V

T

T

L

M

A

A

D

D

A

L

F

C

F

L

A

V

P

P

I

Q

A

V

V

A

R
x
N

L

A

R

E

T
x
R

Y

F

R

K

V

V

K

D

L

L

S

T

binding glutathione: S10 (= S13), S11 (= S14), C12 (≠ W15), R15 (= R18), L34 (= L37), Q41 (≠ R45), Q54 (≠ K54), V55 (= V55), Q67 (≠ D67), S68 (= S68), Q107 (≠ M113), N111 (≠ H119), L112 (≠ D120), S113 (≠ A121)
binding sulfate ion: S10 (= S13), S11 (= S14), Q107 (≠ M113), Q110 (≠ G118), N168 (≠ R172), R171 (≠ T175)

3bbyA Crystal structure of glutathione s-transferase (np_416804.1) from escherichia coli k12 at 1.85 a resolution
30% identity, 73% coverage: 54:206/210 of query aligns to 38:183/191 of 3bbyA

query
sites
3bbyA

K

R

V

V

P

P

L

L

K

Q

T

I

E

D

H

D

G

F

T

E

I

L

A

S

D

E

S

S

L

S

A

A

I

I

A

A

E

E

Y

Y

L

L

A

E

E

D

Q

R

F

F

P

A

D

P

A

P

N

T

-

W

-

E

-

R

L

I

W

Y

P

P

K

L

D
|
D

T

L

A
x
E

A

N

R

R

A

A

Q

R

A

A

R

R

S

Q

A

I

C

Q

A

A

Q

W

M

L

H

R

S

S

G

D

F

L

F

M

A

P

M

I

R

R

G

E

N

E

M

R

P

P

F

T

D

D

L

V

G

V

H

F

-

A

D

G

A

A

A

K

L

K

S

A

P

P

V

L

P

T

A

A

D

E

V

G

Q

K

A

A

D

S

I

A

E

E

R

K

M

L

S

F

A

A

L

M

W

A

A

E

E

H

C

L

R

L

V

V

A

L

A

G

T

Q

E

-

S

-

G

-

P

P

Y

N

L

L

F

F

G

G

R

E

I

W

T

C

L

I

A

A

D

D

A

T

F

D

F

L

A

A

P

L

I

M

A

I

V

N

R

R

L

L

R

V

T

L

Y

H

R

-

V

-

K

-

L

-

S

-

V

-

A

G

D

D

E

E

A

V

Y

-

V

P

E

E

T

R

L

L

Y

V

Q

D

W

Y

P

A

A

T

F

F

K

Q

A

-

W

W

Q

Q

K

R

A

A

G

S

L

V

E

Q

binding calcium ion: D75 (= D88), E77 (≠ A90)

7zvpA Crystal structure of poplar glutathione transferase u19 in complex with glutathione (see paper)
38% identity, 41% coverage: 10:96/210 of query aligns to 4:93/216 of 7zvpA

query
sites
7zvpA

K

K

L

L

H

H

S

G

S

F

W

W

-

A

-
x
S

-

P

-
x
F

S

S

L

Y

R

R

G

V

A

I

L

W

A

A

L

L

D

K

L

L

A

K

G

G

A

V

S

E

Y

F

T

-

E

-

E

E

L

Y

I

I

K

E

L

E

N

D

Q
x
L

P

A

D

N

T
x
K

R

S

E

E

R

L

L

L

K

K

H

Y

S

N

P

P

T

V

G

Y

K

K

-
x
Q

V
x
I

P
|
P

L

V

L

F

K

V

T

H

E

G

H

G

G

K

T

P

I

I

A

A

D
x
E

S
|
S

L

L

A

V

I

I

A

L

E

E

Y

Y

L

I

A

E

E

E

Q

T

F

W

P

P

D

E

A

N

N

P

L

L

W

L

P

P

K

T

D

D

T

P

A

Y

A

E

R

R

A

A

Q

M

A

A

R

R

binding S-Hydroxy-Glutathione: S11 (vs. gap), F13 (vs. gap), L35 (≠ Q39), K38 (≠ T42), Q51 (vs. gap), I52 (≠ V55), P53 (= P56), E64 (≠ D67), S65 (= S68)

6gicB Crystal structure of glutathione transferase omega 2s from trametes versicolor in complex with oxyresveratrol
29% identity, 78% coverage: 13:176/210 of query aligns to 13:172/237 of 6gicB

query
sites
6gicB

S

S

S
x
P

W
x
Y

S

G

L

H

R

R

G

A

A

H

L

I

A

A

L

L

D

E

L

E

A

A

G

G

A

A

S

E

Y

Y

T

T

E

L

E

C

L

Q

I

I

K

N

L

V

N

H

Q

R

P

-

D

D

T

K

R

P

E

E

R

W

L

Y

L

K

K

R

H

V

S

N

P

P

T

L

G

G

K

K

V

V

P

P

L

A

L

I

-

T

-

F

-

G

-

P

-

Q

-

V

-

P

-

D

-

E

-

P

K

S

T

P

E

E

H

S

G

E

T

K

I

L

A

V

D

E

S

S

L
|
L

A

A

I

L

A

L

E
|
E

Y

F

L

V

A

A

E

D

Q

V

F

F

P

P

D

E

A

A

N

K

L

L

W

L

P

P

K

A

D

S

T

P

A

V

A

Q

R

R

A

A

Q

R

A

A

R
|
R

S

A

A

-

C

-

A

-

Q

-

M

-

H

-

S

-

G

-

F

F

F

I

A
|
A

M

I

R

Y

G
x
Q

N
|
N

M

Y

P

L

F
x
H

D
|
D

L
x
Q

G
x
F

H
x
R

D
|
D

A

A

A

F

L
x
F

-

R

-

G

S
x
E

P

P

V

V

P

G

A

P

D

F

V

L

Q

Q

A

A

D

-

I

-

E

-

R

-

M

-

S

-

A

-

L

-

W

-

A

L

E

E

C

T

R

L

V

Q

A

S

A

A

T

L

E

P

S

P

G

A

P

G

Y

F

L

A

F

V

G

G

R

E

I

W

T

S

L

L

A

A

D

E

A

A

F

A

F

V

A

A

P

P

I
x
F

A

L

V

A

R
|
R

L

M

R

M

T

L

Y
|
Y

binding trans-oxyresveratrol: P14 (≠ S14), Y15 (≠ W15), H118 (≠ F115), D119 (= D116), F121 (≠ G118), R122 (≠ H119), F126 (≠ L123), F165 (≠ I169), R168 (= R172), Y172 (= Y176)
binding cis-oxyresveratrol: L80 (= L69), E84 (= E73), R107 (= R96), A111 (= A108), Q114 (≠ G111), N115 (= N112)
binding magnesium ion: Q120 (≠ L117), D123 (= D120), E129 (≠ S124)

6gibB Crystal structure of glutathione transferase omega 2s from trametes versicolor
29% identity, 78% coverage: 13:176/210 of query aligns to 13:172/237 of 6gibB

query
sites
6gibB

S

S

S

P

W

Y

S

G

L

H

R

R

G

A

A

H

L

I

A

A

L

L

D

E

L

E

A

A

G

G

A

A

S

E

Y

Y

T

T

E

L

E

C

L

Q

I

I

K

N

L

V

N

H

Q

R

P

-

D

D

T

K

R

P

E

E

R

W

L

Y

L

K

K

R

H

V

S

N

P

P

T

L

G

G

K

K

V

V

P

P

L

A

L

I

-

T

-

F

-

G

-

P

-

Q

-

V

-

P

-

D

-

E

-

P

K

S

T

P

E

E

H

S

G

E

T

K

I

L

A

V

D

E

S

S

L

L

A

A

I

L

A

L

E

E

Y

F

L

V

A

A

E

D

Q

V

F

F

P

P

D

E

A

A

N

K

L

L

W

L

P

P

K

A

D

S

T

P

A

V

A

Q

R

R

A

A

Q

R

A

A

R

R

S

A

A

-

C

-

A

-

Q

-

M

-

H

-

S

-

G

-

F

F

F

I

A

A

M

I

R

Y

G

Q

N

N

M

Y

P

L

F

H

D

D

L
x
Q

G

F

H

R

D
|
D

A

A

A

F

L

F

-

R

-

G

S
x
E

P

P

V

V

P

G

A

P

D

F

V

L

Q

Q

A

A

D

-

I

-

E

-

R

-

M

-

S

-

A

-

L

-

W

-

A

L

E

E

C

T

R

L

V

Q

A

S

A

A

T

L

E

P

S

P

G

A

P

G

Y

F

L

A

F

V

G

G

R

E

I

W

T

S

L

L

A

A

D

E

A

A

F

A

F

V

A

A

P

P

I

F

A

L

V

A

R

R

L

M

R

M

T

L

Y

Y

binding magnesium ion: Q120 (≠ L117), D123 (= D120), E129 (≠ S124)

8ax1A Crystal structure of trametes versicolor glutathione transferase omega 3s in complex with hydroxy-tetranitro-nitrosyl-ruthenate (see paper)
29% identity, 78% coverage: 13:176/210 of query aligns to 11:171/240 of 8ax1A

query
sites
8ax1A

S
|
S

S
x
P

W
x
Y

S

A

L

H

R

R

G

V

A

R

L

I

A

A

L

L

D

E

L

E

A

A

G

G

A

A

S

E

Y

Y

T

T

E

T

E

Y

L

D

I

V

K

D

L
x
I

-
x
L

-

R

N

N

Q

M

P

P

D

D

T

W

R

F

E

P

R

L

L

V

L

-

K

-

H

-

S

N

P

P

T

L

G

K

K
|
K

V
x
I

P

P

L

A

L

M

-

T

-

F

-

G

-

P

-

E

-

V

-

P

-

D

-

Q

-

P

K

S

T

P

E

E

H

S

G

A

T

K

I

I

A

A

D

E

S

S

L

L

A

A

I

M

A

L

E

E

Y

F

L

I

A

A

E

D

Q

L

F

F

P

P

D

D

A

A

N

K

L

L

W

L

P

P

K

T

D

D

T

P

A

V

A

L

R

R

A

A

Q

R

A

A

R

R

S

T

A

-

C

-

A

-

Q

-

M

-

H

-

S

-

G

-

F

F

F

M

A

A

M

L

R

Y

G

E

N

N

M

Y

P

V

F

N

D

G

L

Q

G

F

H

R

D

D

A

V

A

W

L

F

S

L

P

G

V

T

P

P

A

A

D

D

V

P

Q

L

A

L

D

Q

I

A

E

L

R

E

M

M

S

-

A

-

L

-

W

-

A

-

E

-

C

L

R

Q

V

G

A

A

A

L

T

P

E

P

S

D

G

G

P

G

Y

F

L

A

F

A

G

G

R

E

I

W

T

S

L

I

A

A

D

D

A

A

F

A

F

V

A

I

P

P

I

F

A

L

V

A

R

R

L

M

R
x
F

T

P

Y

Y

binding tetranitro-nitroso-oxidanyl-ruthenium(2-): S11 (= S13), P12 (≠ S14), Y13 (≠ W15), I35 (≠ L37), L36 (vs. gap), K51 (= K54), I52 (≠ V55), F169 (≠ R174)

Sites not aligning to the query:

binding tetranitro-nitroso-oxidanyl-ruthenium(2-): 10, 200, 203, 204, 207

6f51A Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with glutathionyl-phenylacetophenone (see paper)
29% identity, 78% coverage: 13:176/210 of query aligns to 11:171/240 of 6f51A

query
sites
6f51A

S
|
S

S
x
P

W
x
Y

S

A

L

H

R

R

G

V

A

R

L

I

A

A

L

L

D

E

L

E

A

A

G

G

A

A

S

E

Y

Y

T

T

E

T

E

Y

L

D

I

V

K

D

L
x
I

-
x
L

-

R

N

N

Q

M

P

P

D

D

T

W

R

F

E

P

R

L

L

V

L

-

K

-

H

-

S

N

P

P

T

L

G
x
K

K
|
K

V
x
I

P
|
P

L

A

L

M

-

T

-

F

-

G

-

P

-

E

-

V

-

P

-

D

-

Q

-

P

K

S

T

P

E

E

H

S

G

A

T

K

I

I

A

A

D
x
E

S
|
S

L

L

A

A

I

M

A

L

E

E

Y

F

L

I

A

A

E

D

Q

L

F

F

P

P

D

D

A

A

N

K

L

L

W

L

P

P

K

T

D

D

T

P

A

V

A

L

R

R

A

A

Q

R

A

A

R

R

S

T

A

-

C

-

A

-

Q

-

M

-

H

-

S

-

G

-

F

F

F

M

A

A

M

L

R

Y

G

E

N
|
N

M
x
Y

P

V

F

N

D

G

L

Q

G
x
F

H

R

D

D

A

V

A
x
W

L
x
F

S

L

P

G

V

T

P

P

A

A

D

D

V

P

Q

L

A

L

D

Q

I

A

E

L

R

E

M

M

S

-

A

-

L

-

W

-

A

-

E

-

C

L

R

Q

V

G

A

A

A

L

T

P

E

P

S

D

G

G

P

G

Y

F

L

A

F

A

G

G

R

E

I

W

T

S

L

I

A

A

D

D

A

A

F

A

F

V

A

I

P

P

I
x
F

A

L

V

A

R
|
R

L

M

R

F

T

P

Y

Y

binding L-gamma-glutamyl-S-(2-biphenyl-4-yl-2-oxoethyl)-L-cysteinylglycine: S11 (= S13), P12 (≠ S14), Y13 (≠ W15), I35 (≠ L37), L36 (vs. gap), K50 (≠ G53), K51 (= K54), I52 (≠ V55), P53 (= P56), E76 (≠ D67), S77 (= S68), N113 (= N112), Y114 (≠ M113), F119 (≠ G118), W123 (≠ A122), F124 (≠ L123), F164 (≠ I169), R167 (= R172)

Sites not aligning to the query:

binding L-gamma-glutamyl-S-(2-biphenyl-4-yl-2-oxoethyl)-L-cysteinylglycine: 10

8ax0A Crystal structure of trametes versicolor glutathione transferase omega 3s in complex with sodium nitroprusside (see paper)
29% identity, 78% coverage: 13:176/210 of query aligns to 12:172/241 of 8ax0A

query
sites
8ax0A

S
|
S

S
x
P

W
x
Y

S

A

L

H

R

R

G

V

A

R

L

I

A

A

L

L

D

E

L

E

A

A

G

G

A

A

S

E

Y

Y

T

T

E

T

E

Y

L

D

I

V

K

D

L

I

-

L

-

R

N

N

Q

M

P

P

D

D

T

W

R

F

E

P

R

L

L

V

L

-

K

-

H

-

S

N

P

P

T

L

G

K

K

K

V

I

P

P

L

A

L

M

-

T

-

F

-

G

-

P

-

E

-

V

-

P

-

D

-

Q

-

P

K

S

T

P

E

E

H

S

G

A

T

K

I

I

A

A

D

E

S

S

L

L

A

A

I

M

A

L

E

E

Y

F

L

I

A

A

E

D

Q

L

F

F

P

P

D

D

A

A

N

K

L

L

W

L

P

P

K

T

D

D

T

P

A

V

A

L

R

R

A

A

Q

R

A

A

R

R

S

T

A

-

C

-

A

-

Q

-

M

-

H

-

S

-

G

-

F

F

F

M

A

A

M

L

R

Y

G

E

N

N

M

Y

P

V

F

N

D

G

L

Q

G

F

H
x
R

D

D

A

V

A

W

L
x
F

S

L

P

G

V

T

P

P

A

A

D

D

V

P

Q

L

A

L

D

Q

I

A

E

L

R

E

M

M

S

-

A

-

L

-

W

-

A

-

E

-

C

L

R

Q

V

G

A

A

A

L

T

P

E

P

S

D

G

G

P

G

Y

F

L

A

F

A

G

G

R

E

I

W

T

S

L

I

A

A

D

D

A

A

F

A

F

V

A

I

P

P

I

F

A

L

V

A

R

R

L

M

R
x
F

T

P

Y

Y

binding Nitroprusside ion: S12 (= S13), P13 (≠ S14), Y14 (≠ W15), R121 (≠ H119), F125 (≠ L123), F170 (≠ R174)

Sites not aligning to the query:

binding Nitroprusside ion: 11, 201, 204, 205, 208, 230, 233

8awzA Crystal structure of trametes versicolor glutathione transferase omega 3s in complex with dinitrosyl glutathionyl iron complex (dngic) (see paper)
29% identity, 78% coverage: 13:176/210 of query aligns to 12:172/241 of 8awzA

query
sites
8awzA

S
|
S

S

P

W
x
Y

S

A

L

H

R

R

G

V

A

R

L

I

A

A

L

L

D

E

L

E

A

A

G

G

A

A

S

E

Y

Y

T

T

E

T

E

Y

L

D

I

V

K

D

L
x
I

-
x
L

-

R

N

N

Q

M

P

P

D

D

T

W

R

F

E

P

R

L

L

V

L

-

K

-

H

-

S

N

P

P

T

L

G
x
K

K
|
K

V
x
I

P
|
P

L

A

L

M

-

T

-

F

-

G

-

P

-

E

-

V

-

P

-

D

-

Q

-

P

K

S

T

P

E

E

H

S

G

A

T

K

I

I

A

A

D
x
E

S
|
S

L

L

A

A

I

M

A

L

E

E

Y

F

L

I

A

A

E

D

Q

L

F

F

P

P

D

D

A

A

N

K

L

L

W

L

P

P

K

T

D

D

T

P

A

V

A

L

R

R

A

A

Q

R

A

A

R

R

S

T

A

-

C

-

A

-

Q

-

M

-

H

-

S

-

G

-

F

F

F

M

A

A

M

L

R

Y

G

E

N
|
N

M
x
Y

P

V

F

N

D

G

L

Q

G

F

H
x
R

D

D

A

V

A

W

L

F

S

L

P

G

V

T

P

P

A

A

D

D

V

P

Q

L

A

L

D

Q

I

A

E

L

R

E

M

M

S

-

A

-

L

-

W

-

A

-

E

-

C

L

R

Q

V

G

A

A

A

L

T

P

E

P

S

D

G

G

P

G

Y

F

L

A

F

A

G

G

R

E

I

W

T

S

L

I

A

A

D

D

A

A

F

A

F

V

A

I

P

P

I

F

A

L

V

A

R

R

L

M

R

F

T

P

Y

Y

binding glutathione: S12 (= S13), Y14 (≠ W15), I36 (≠ L37), L37 (vs. gap), K51 (≠ G53), K52 (= K54), I53 (≠ V55), P54 (= P56), E77 (≠ D67), S78 (= S68), N114 (= N112), Y115 (≠ M113)
binding nitric oxide: Y14 (≠ W15), R121 (≠ H119)

Sites not aligning to the query:

binding glutathione: 11

Query Sequence

>PfGW456L13_1835 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_1835
MSLHLIIGDKLHSSWSLRGALALDLAGASYTEELIKLNQPDTRERLLKHSPTGKVPLLKT
EHGTIADSLAIAEYLAEQFPDANLWPKDTAARAQARSACAQMHSGFFAMRGNMPFDLGHD
AALSPVPADVQADIERMSALWAECRVAATESGPYLFGRITLADAFFAPIAVRLRTYRVKL
SVADEAYVETLYQWPAFKAWQKAGLEEIER

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory