Comparing PfGW456L13_2414 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_2414 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
3i5tA Crystal structure of aminotransferase prk07036 from rhodobacter sphaeroides kd131
46% identity, 88% coverage: 47:461/472 of query aligns to 32:439/444 of 3i5tA
Sites not aligning to the query:
5kr5A Directed evolution of transaminases by ancestral reconstruction. Using old proteins for new chemistries
43% identity, 94% coverage: 16:460/472 of query aligns to 4:453/455 of 5kr5A
6gwiB The crystal structure of halomonas elongata amino-transferase (see paper)
41% identity, 94% coverage: 21:463/472 of query aligns to 10:449/450 of 6gwiB
5kr6B Directed evolution of transaminases by ancestral reconstruction. Using old proteins for new chemistries
42% identity, 96% coverage: 13:463/472 of query aligns to 5:460/460 of 5kr6B
5kquC Directed evolution of transaminases by ancestral reconstruction. Using old proteins for new chemistries
41% identity, 96% coverage: 13:463/472 of query aligns to 3:458/459 of 5kquC
5kr3A Directed evolution of transaminases by ancestral reconstruction. Using old proteins for new chemistries
41% identity, 95% coverage: 16:463/472 of query aligns to 7:457/458 of 5kr3A
6io1B Crystal structure of a novel thermostable (s)-enantioselective omega- transaminase from thermomicrobium roseum (see paper)
39% identity, 95% coverage: 13:459/472 of query aligns to 4:446/448 of 6io1B
7ypmA Crystal structure of transaminase cc1012 complexed with plp and l- alanine (see paper)
41% identity, 96% coverage: 13:465/472 of query aligns to 2:453/454 of 7ypmA
7ypnD Crystal structure of transaminase cc1012 mutant m9 complexed with plp (see paper)
41% identity, 96% coverage: 13:465/472 of query aligns to 2:453/455 of 7ypnD
7qx0B Transaminase structure of plurienzyme (tr2e2) in complex with plp (see paper)
40% identity, 95% coverage: 10:459/472 of query aligns to 1:438/443 of 7qx0B
7qx3A Structure of the transaminase tr2e2 with eos (see paper)
41% identity, 88% coverage: 43:458/472 of query aligns to 4:416/422 of 7qx3A
6g4dB Crystal structure of the omega transaminase from pseudomonas jessenii in complex with plp (see paper)
39% identity, 92% coverage: 15:450/472 of query aligns to 1:436/453 of 6g4dB
6g4fA Crystal structure of the omega transaminase from pseudomonas jessenii in complex with pmp (see paper)
39% identity, 92% coverage: 15:450/472 of query aligns to 1:436/451 of 6g4fA
6g4eA Crystal structure of the omega transaminase from pseudomonas jessenii in complex with plp and 6-aminohexanoate (6-aca) (see paper)
39% identity, 92% coverage: 15:450/472 of query aligns to 1:436/451 of 6g4eA
6fyqA The crystal structure of a new transaminase from the marine bacterium virgibacillus (see paper)
38% identity, 95% coverage: 17:463/472 of query aligns to 3:442/443 of 6fyqA
6s4gA Crystal structure of the omega transaminase from chromobacterium violaceum in complex with pmp (see paper)
37% identity, 96% coverage: 15:467/472 of query aligns to 3:452/453 of 6s4gA
7q9xAAA Probable aminotransferase
37% identity, 96% coverage: 15:467/472 of query aligns to 4:453/455 of 7q9xAAA
4a6tC Crystal structure of the omega transaminase from chromobacterium violaceum in complex with plp (see paper)
37% identity, 96% coverage: 15:467/472 of query aligns to 4:453/455 of 4a6tC
3fcrA Crystal structure of putative aminotransferase (yp_614685.1) from silicibacter sp. Tm1040 at 1.80 a resolution
38% identity, 93% coverage: 16:455/472 of query aligns to 7:453/458 of 3fcrA
3gjuA Crystal structure of a putative aminotransferase (mll7127) from mesorhizobium loti maff303099 at 1.55 a resolution
37% identity, 93% coverage: 21:461/472 of query aligns to 13:458/458 of 3gjuA
>PfGW456L13_2414 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_2414
MATPTRTVFSPADESRLVKADKAHHMHGYHVFDEHAEQGSLNIVAGDGAYIYDTQGNRFL
DAVGGMWCTNIGLGREEMAEAIADQVRQLAYSNPFSDMSNNVAIELCEKLASLAPGDLDH
VFLTTGGSTAVDTAYRLIQYYQNCRGKPEKKHIIARFNAYHGSTTLTMSIGNKAADRVPE
FDYTNPLIHHVSNPNPYRAPDGMDEAQFLEFLVKEFEDKILSIGADKVAGFFAEPIMGSG
GVIIPPRGYLKRMWDVCQRYDILFVADEVVTSFGRLGKFFASYEVFDVQPDIITTAKGLT
SAYLPLGACIFSERIWKVIAEPGKGRCFTHGFTYSGHPVCCTAALKNIEIIERENLLAHV
DTVGAYLEERLATLRDLPLVGDVRCQKLMACVEFVADKRTKALFPDEINIGEKIHVRAQA
RGLLVRPIMHLNVMSPPLILTSVQVDEIVETLRTCILEVAAELEASGQYAGQ
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory