Comparing PfGW456L13_3340 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_3340 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8ewoA Crystal structure of putative glyoxylase ii from pseudomonas aeruginosa
69% identity, 100% coverage: 1:255/255 of query aligns to 2:259/259 of 8ewoA
6rz0A Crystal structure of escherichia coli glyoxalase ii
48% identity, 100% coverage: 2:255/255 of query aligns to 1:251/251 of 6rz0A
2qedA Crystal structure of salmonella thyphimurium lt2 glyoxalase ii (see paper)
46% identity, 100% coverage: 2:255/255 of query aligns to 2:252/252 of 2qedA
Q8ZRM2 Hydroxyacylglutathione hydrolase; Glyoxalase II; Glx II; EC 3.1.2.6 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
46% identity, 100% coverage: 2:255/255 of query aligns to 1:251/251 of Q8ZRM2
Q9SID3 Hydroxyacylglutathione hydrolase 2, mitochondrial; Glyoxalase II; Glx II; EC 3.1.2.6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
45% identity, 91% coverage: 2:232/255 of query aligns to 71:310/324 of Q9SID3
2q42A Ensemble refinement of the protein crystal structure of glyoxalase ii from arabidopsis thaliana gene at2g31350 (see paper)
45% identity, 91% coverage: 2:232/255 of query aligns to 1:240/254 of 2q42A
O24496 Hydroxyacylglutathione hydrolase cytoplasmic; Glyoxalase II; Glx II; EC 3.1.2.6 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
44% identity, 89% coverage: 2:229/255 of query aligns to 1:236/258 of O24496
Sites not aligning to the query:
1qh5B Human glyoxalase ii with s-(n-hydroxy-n-bromophenylcarbamoyl) glutathione (see paper)
41% identity, 100% coverage: 2:255/255 of query aligns to 1:255/260 of 1qh5B
1qh5A Human glyoxalase ii with s-(n-hydroxy-n-bromophenylcarbamoyl) glutathione (see paper)
41% identity, 100% coverage: 2:255/255 of query aligns to 1:255/260 of 1qh5A
1qh3A Human glyoxalase ii with cacodylate and acetate ions present in the active site (see paper)
41% identity, 100% coverage: 2:255/255 of query aligns to 1:255/260 of 1qh3A
Q16775 Hydroxyacylglutathione hydrolase, mitochondrial; Glyoxalase II; Glx II; EC 3.1.2.6 from Homo sapiens (Human) (see paper)
41% identity, 100% coverage: 2:255/255 of query aligns to 49:303/308 of Q16775
2p18A Crystal structure of the leishmania infantum glyoxalase ii (see paper)
31% identity, 91% coverage: 2:232/255 of query aligns to 13:270/283 of 2p18A
4ysbA Crystal structure of ethe1 from myxococcus xanthus (see paper)
32% identity, 74% coverage: 1:188/255 of query aligns to 1:191/225 of 4ysbA
2zwrB Crystal structure of ttha1623 from thermus thermophilus hb8 (see paper)
34% identity, 55% coverage: 28:167/255 of query aligns to 26:184/207 of 2zwrB
2zziA Crystal structure of ttha1623 in a di-iron-bound form (see paper)
34% identity, 55% coverage: 28:167/255 of query aligns to 24:182/198 of 2zziA
O95571 Persulfide dioxygenase ETHE1, mitochondrial; Ethylmalonic encephalopathy protein 1; Hepatoma subtracted clone one protein; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Homo sapiens (Human) (see 4 papers)
25% identity, 82% coverage: 13:222/255 of query aligns to 35:248/254 of O95571
Sites not aligning to the query:
2xf4A Crystal structure of salmonella enterica serovar typhimurium ycbl (see paper)
34% identity, 53% coverage: 3:138/255 of query aligns to 4:160/210 of 2xf4A
Sites not aligning to the query:
4chlB Human ethylmalonic encephalopathy protein 1 (hethe1) (see paper)
25% identity, 82% coverage: 13:222/255 of query aligns to 19:232/237 of 4chlB
Q9C8L4 Persulfide dioxygenase ETHE1 homolog, mitochondrial; Glyoxalase II; Glx II; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
31% identity, 62% coverage: 11:169/255 of query aligns to 62:234/294 of Q9C8L4
2gcuA X-ray structure of gene product from arabidopsis thaliana at1g53580 (see paper)
29% identity, 79% coverage: 11:211/255 of query aligns to 13:219/244 of 2gcuA
>PfGW456L13_3340 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_3340
MIQITALPAFTDNYIWLLQDHGSKRCAVVDPGDAGPVQAWLAANPGWVLSDILITHHHHD
HVGGVEQLKKATDAKVYGPASETIPARDVALKDNDKVCVLGWDFDVLAVPGHTLGHIAYY
HHGLLFCGDTLFAAGCGRLFEGTPQQMYSSLTRLAGLPEDTLVYCTHEYTLGNLKFAAAV
EPNNPHTAERLAKVTRQRESGIMTLPSTLALEKLTNPFLRSGETSVKEKADERTGTDNSA
PDMVFAALRAWKDRF
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory