SitesBLAST

SitesBLAST – Find functional sites

SitesBLAST

Comparing PfGW456L13_3823 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_3823 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 1 hits to proteins with known functional sites (download)

3zo7B Crystal structure of clcfe27a with substrate (see paper)
50% identity, 98% coverage: 1:94/96 of query aligns to 1:94/94 of 3zo7B

query
sites
3zo7B

M

M

L

L

F

Y

H

L

V

V

K

R

M

M

T

T

V

V

N

N

L

L

P

P

V

R

D

N

M

L

N

D

P

P

E

R

V

E

A

E

A

E

K

R

L

L

K

K

A

A

D

S

E
x
A

K

K

A

A

L

R

A

S

Q

R

R

T

L

L

Q

Q

E

E

Q

Q

G

G

K

Q

W

W

R

R

H

Y

L

L

W

W

R
|
R

I

T

A

T

G

G

H

K

Y

Y

A

G

N
|
N

Y

I

S

S

V

V

F

F

D

D

V

V

D

N

S

S

V

H

Q

D

E

E

L

L

H

H

D

E

L

I

L

L

M

W

Q

S

L

L

P

P

L
x
F

F

F

P

P

Y

Y

M

L

A

T

I

I

E

D

I

V

D

E

A

P

M

L

C

S

R

H

H

H

P

P

S

A

S

R

I

V

R

G

D

K

D

D

binding (2S)-2-chloranyl-2-[(2R)-5-oxidanylidene-2H-furan-2-yl]ethanoic acid: A27 (≠ E27), R45 (= R45), N52 (= N52), F73 (≠ L73)

Query Sequence

>PfGW456L13_3823 FitnessBrowser__pseudo13_GW456_L13:PfGW456L13_3823
MLFHVKMTVNLPVDMNPEVAAKLKADEKALAQRLQEQGKWRHLWRIAGHYANYSVFDVDS
VQELHDLLMQLPLFPYMAIEIDAMCRHPSSIRDDDR

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory