Comparing PfGW456L13_4990 Phosphate acetyltransferase (EC 2.3.1.8) to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 10 hits to proteins with known functional sites (download)
Q8ZND6 Phosphate acetyltransferase; Phosphotransacetylase; EC 2.3.1.222; EC 2.3.1.8 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
51% identity, 98% coverage: 11:702/706 of query aligns to 5:712/714 of Q8ZND6
6ioxA Crystal structure of porphyromonas gingivalis phosphotransacetylase in complex with acetyl-coa (see paper)
42% identity, 45% coverage: 385:699/706 of query aligns to 11:334/339 of 6ioxA
1xcoD Crystal structure of a phosphotransacetylase from bacillus subtilis in complex with acetylphosphate (see paper)
42% identity, 43% coverage: 395:699/706 of query aligns to 20:324/325 of 1xcoD
2af3C Phosphotransacetylase from methanosarcina thermophila soaked with coenzyme a (see paper)
39% identity, 45% coverage: 381:700/706 of query aligns to 3:328/332 of 2af3C
P38503 Phosphate acetyltransferase; Phosphotransacetylase; EC 2.3.1.8 from Methanosarcina thermophila (see 2 papers)
39% identity, 45% coverage: 381:700/706 of query aligns to 4:329/333 of P38503
Sites not aligning to the query:
6zngF Maeb full-length acetyl-coa bound state (see paper)
34% identity, 47% coverage: 371:699/706 of query aligns to 414:743/753 of 6zngF
Sites not aligning to the query:
P76558 NADP-dependent malic enzyme; NADP-ME; EC 1.1.1.40 from Escherichia coli (strain K12) (see paper)
29% identity, 46% coverage: 380:704/706 of query aligns to 429:759/759 of P76558
Sites not aligning to the query:
7t85A Crystal structure of the n-terminal domain of the phosphate acetyltransferase from escherichia coli
36% identity, 27% coverage: 11:199/706 of query aligns to 5:169/173 of 7t85A
3u9eB The crystal structure of a possible phosphate acetyl/butaryl transferase (from listeria monocytogenes egd-e) in complex with coa.
29% identity, 20% coverage: 539:682/706 of query aligns to 129:274/288 of 3u9eB
Sites not aligning to the query:
3uf6A The crystal structure of a possible phosphate acetyl/butaryl transferase (from listeria monocytogenes egd-e) in complex with cod (3'-dephosphocoenzyme a)
29% identity, 20% coverage: 539:682/706 of query aligns to 127:272/285 of 3uf6A
Sites not aligning to the query:
>PfGW456L13_4990 Phosphate acetyltransferase (EC 2.3.1.8)
MLLQRIRMQTFFIAPTDFGVGLTSISLGLVRTLERAGLKVGFFKPIAQPHPGDTGPERST
ELVARTHGLKPPQPLGLAHVERMLGDGQLDELLEEIITLYQQAAIGKDVLIVEGMVPTRS
ASYAARVNLHLAKSLDAEVILVSAPENEVLTELSGRVELQAQLFGGPKDPKVLGVILNKV
KTEESMEAFATRLKEHSPLLRSGDFRLLGCIPFQPELNAPRTRDVADLMGAQVLNAGDYE
TRRMTKIIICARTMRNTVELLKPGVLVVTPGDRDDIILAVSLAALNGVPLAGLLLTSDTL
PDPRIMDLCRGALQAGLPVLSVSTGSYDTANLLNGLNKEIPIDDRERAEIITDFIAGHLD
ANWLHQRCGTPREMRLSPAVFRYQLIQRAQAANKRIVLPEGSEPLTVQAAAICQARGIAR
CVLLAKPEDVQAVARAQGIELPPGLEIIDPDLIRERYVEPMVALRKSKSLNAPMAEQQLE
DTVVIGTMMLALDEVDGLVSGVINTTANTIRPALQLIKTAPGCTLVSSVFFMLFPEEVLV
YGDCVMNPHPSASELAEIALQSADSAAAFGITPRVAMISYSSGESASGEEVEKVREATLL
AHEQQHSLLIDGPLQYDAAANESVARQLAPNSQVAGRATVYVFPDLNTGNTTHKAVQRSA
DCVSLGPMLQGLRKPVNDLPRGAQVDDIVYTIALTAIQAANRPMDV
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory