Comparing RR42_RS06535 FitnessBrowser__Cup4G11:RR42_RS06535 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4p8bA Crystal structure of a trap periplasmic solute binding protein from ralstonia eutropha h16 (h16_a1328), target efi-510189, with bound (s)-2-hydroxy-2-methyl-3-oxobutanoate ((s)-2-acetolactate) (see paper)
95% identity, 92% coverage: 29:342/342 of query aligns to 1:314/314 of 4p8bA
4pdhA Crystal structure of a trap periplasmic solute binding protein from polaromonas sp js666 (bpro_1871, target efi-510164) bound to d- erythronate (see paper)
34% identity, 82% coverage: 50:328/342 of query aligns to 21:290/301 of 4pdhA
Sites not aligning to the query:
4pakA Crystal structure of a trap periplasmic solute binding protein from verminephrobacter eiseniae ef01-2 (veis_3954, target efi-510324) a nephridial symbiont of the earthworm eisenia foetida, bound to (r)- pantoic acid (see paper)
33% identity, 82% coverage: 50:328/342 of query aligns to 24:293/304 of 4pakA
Sites not aligning to the query:
4p9kA Crystal structure of a trap periplasmic solute binding protein from verminephrobacter eiseniae ef01-2 (veis_3954, target efi-510324) a nephridial symbiont of the earthworm eisenia foetida, bound to d- erythronate with residual density suggestive of superposition with copurified alternative ligand. (see paper)
33% identity, 82% coverage: 50:328/342 of query aligns to 23:292/303 of 4p9kA
Sites not aligning to the query:
7bbrA Crystal structure of the sugar acid binding protein dctpam from advenella mimigardefordensis strain dpn7t (see paper)
30% identity, 85% coverage: 44:332/342 of query aligns to 19:300/310 of 7bbrA
Sites not aligning to the query:
7bcrA Crystal structure of the sugar acid binding protein dctpam from advenella mimigardefordensis strain dpn7t in complex with galactonate (see paper)
30% identity, 85% coverage: 44:332/342 of query aligns to 18:299/310 of 7bcrA
Sites not aligning to the query:
7bcpA Crystal structure of the sugar acid binding protein dctpam from advenella mimigardefordensis strain dpn7t in complex with gluconate (see paper)
30% identity, 85% coverage: 44:332/342 of query aligns to 18:299/310 of 7bcpA
Sites not aligning to the query:
7bcoA Crystal structure of the sugar acid binding protein dctpam from advenella mimigardefordensis strain dpn7t in complex with d-foconate (see paper)
30% identity, 85% coverage: 44:332/342 of query aligns to 18:299/310 of 7bcoA
Sites not aligning to the query:
7bcnA Crystal structure of the sugar acid binding protein dctpam from advenella mimigardefordensis strain dpn7t in complex with xylonic acid (see paper)
30% identity, 85% coverage: 44:332/342 of query aligns to 18:299/310 of 7bcnA
4nq8B Crystal structure of a trap periplasmic solute binding protein from bordetella bronchispeptica (bb3421), target efi-510039, with density modeled as pantoate (see paper)
29% identity, 86% coverage: 34:327/342 of query aligns to 5:292/301 of 4nq8B
4pddA Crystal structure of a trap periplasmic solute binding protein from polaromonas sp js666 (bpro_0088, target efi-510167) bound to d- erythronate (see paper)
28% identity, 86% coverage: 45:337/342 of query aligns to 16:299/303 of 4pddA
Sites not aligning to the query:
4p3lA Crystal structure of a trap periplasmic solute binding protein from chromohalobacter salexigens dsm 3043 (csal_2479), target efi-510085, with bound glucuronate, spg p6122 (see paper)
29% identity, 84% coverage: 41:326/342 of query aligns to 11:287/303 of 4p3lA
Sites not aligning to the query:
4pf8A Crystal structure of a trap periplasmic solute binding protein from sulfitobacter sp. Nas-14.1 (target efi-510299) with bound beta-d- galacturonate (see paper)
31% identity, 82% coverage: 43:323/342 of query aligns to 12:283/300 of 4pf8A
Sites not aligning to the query:
4oanA Crystal structure of a trap periplasmic solute binding protein from rhodopseudomonas palustris haa2 (rpb_2686), target efi-510221, with density modeled as (s)-2-hydroxy-2-methyl-3-oxobutanoate ((s)-2- acetolactate) (see paper)
31% identity, 84% coverage: 56:341/342 of query aligns to 32:310/312 of 4oanA
Sites not aligning to the query:
P44542 Sialic acid-binding periplasmic protein SiaP; Extracytoplasmic solute receptor protein SiaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 2 papers)
28% identity, 96% coverage: 1:328/342 of query aligns to 2:314/329 of P44542
4x8rA Crystal structure of a trap periplasmic solute binding protein from rhodobacter sphaeroides (rsph17029_2138, target efi-510205) with bound glucuronate
28% identity, 82% coverage: 43:323/342 of query aligns to 16:287/304 of 4x8rA
Sites not aligning to the query:
2v4cA Structure of sialic acid binding protein (siap) in the presence of kdn (see paper)
30% identity, 82% coverage: 47:328/342 of query aligns to 19:291/309 of 2v4cA
2wx9A Crystal structure of the sialic acid binding periplasmic protein siap (see paper)
30% identity, 82% coverage: 47:328/342 of query aligns to 19:291/308 of 2wx9A
Sites not aligning to the query:
3b50A Structure of h. Influenzae sialic acid binding protein bound to neu5ac. (see paper)
30% identity, 82% coverage: 47:328/342 of query aligns to 19:291/310 of 3b50A
Sites not aligning to the query:
2cexB Structure of a sialic acid binding protein (siap) in the presence of the sialic acid acid analogue neu5ac2en (see paper)
30% identity, 82% coverage: 47:328/342 of query aligns to 18:290/305 of 2cexB
Sites not aligning to the query:
>RR42_RS06535 FitnessBrowser__Cup4G11:RR42_RS06535
MKRRALMLSLAATIAAAALAPAGAMAQSYKAEYKMSLVLGPAFPWGKGGEIWADLVRQRT
SGRINIKLYPGTSLVAGDQTREFSAIRQGVIDMAVGSTINWSPQVKELNLFSLPFLMPDY
KALDALTQGEVGKSIFATLDKSGVVPLAWGENGFREVSNSKREIRKPEDLKGMKLRVVGS
PLYIETFNALGANPTQMSWADAQPAMASGAVDGQENPQSVFAAAKLYTVGQKYVTTWGYV
ADPLIFVVNKQIWESWTPADREIVKQAAIDAGKQETALARKGLVEAGAPAWKDMEAHGVK
VAQLTPAEHDAFRKATAKVYDKWKKQIGVDLVSKAEASIAKR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory