Comparing RR42_RS10005 RR42_RS10005 3-oxoadipate CoA-transferase to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 9 hits to proteins with known functional sites (download)
1o9lA Succinate:coenzyme-a transferase (pig heart)
42% identity, 99% coverage: 4:217/217 of query aligns to 2:231/468 of 1o9lA
3oxoE Succinyl-coa:3-ketoacid coa transferase from pig heart covalently bound to coa (see paper)
42% identity, 99% coverage: 4:217/217 of query aligns to 2:231/462 of 3oxoE
Sites not aligning to the query:
3k6mC Dynamic domains of succinyl-coa:3-ketoacid-coenzyme a transferase from pig heart. (see paper)
42% identity, 99% coverage: 4:217/217 of query aligns to 2:231/466 of 3k6mC
Sites not aligning to the query:
Q29551 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; SCOT; 3-oxoacid CoA-transferase 1; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; SCOT-s; Succinate-coenzyme A transferase; Succinyl-CoA:3-oxoacid CoA transferase; EC 2.8.3.5 from Sus scrofa (Pig) (see 3 papers)
42% identity, 99% coverage: 4:217/217 of query aligns to 41:270/520 of Q29551
Sites not aligning to the query:
1k6dB Crystal structure of acetate coa-transferase alpha subunit (see paper)
39% identity, 97% coverage: 8:217/217 of query aligns to 7:214/219 of 1k6dB
8i3yD Crystal structure of asct from trypanosoma brucei in complex with succinyl-coa.
37% identity, 100% coverage: 2:217/217 of query aligns to 2:232/471 of 8i3yD
8i3yA Crystal structure of asct from trypanosoma brucei in complex with succinyl-coa.
37% identity, 100% coverage: 2:217/217 of query aligns to 2:232/459 of 8i3yA
Sites not aligning to the query:
8i40A Crystal structure of asct from trypanosoma brucei in complex with coa.
37% identity, 100% coverage: 2:217/217 of query aligns to 2:232/467 of 8i40A
Sites not aligning to the query:
2ahvA Crystal structure of acyl-coa transferase from e. Coli o157:h7 (ydif)- thioester complex with coa- 1 (see paper)
24% identity, 97% coverage: 8:217/217 of query aligns to 14:248/512 of 2ahvA
Sites not aligning to the query:
>RR42_RS10005 RR42_RS10005 3-oxoadipate CoA-transferase
MIDKLYATAREAVADVADGATIAIGGFGGAGMPDELIDALIEQGAKDLTVVSNNAGNGDA
GLAALLKARRVRRLMCSFPRQRDAYVFEALYRAGEIELEVIPQGTLAERLRAAGCGIGGF
YTPTGHGTLLAAGKEARRIGARDYVLEYPIHVDVALINAAAADRWGNLVYNKTARNFAPV
MAMAATTTIAAVTRVCELGELDPEAIVTPGIFVKRVV
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory