Comparing RR42_RS13035 FitnessBrowser__Cup4G11:RR42_RS13035 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P0A6C5 Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS; NAGS; EC 2.3.1.1 from Escherichia coli (strain K12) (see paper)
45% identity, 90% coverage: 48:478/478 of query aligns to 8:442/443 of P0A6C5
4i49A Structure of ngnags bound with bisubstrate analog coa-NAG (see paper)
39% identity, 90% coverage: 49:478/478 of query aligns to 3:422/424 of 4i49A
3d2mA Crystal structure of n-acetylglutamate synthase from neisseria gonorrhoeae complexed with coenzyme a and l-glutamate (see paper)
39% identity, 90% coverage: 49:478/478 of query aligns to 3:422/424 of 3d2mA
3b8gA Crysta structure of n-acetylglutamate synthase from neisseria gonorrhoeae complexed with coenzyme a and n-acetyl-glutamate (see paper)
39% identity, 90% coverage: 49:478/478 of query aligns to 3:422/424 of 3b8gA
2r8vA Native structure of n-acetylglutamate synthase from neisseria gonorrhoeae (see paper)
39% identity, 90% coverage: 49:478/478 of query aligns to 3:422/424 of 2r8vA
3d2pA Crystal structure of n-acetylglutamate synthase from neisseria gonorrhoeae complexed with coenzyme a and l-arginine (see paper)
39% identity, 90% coverage: 49:478/478 of query aligns to 3:422/424 of 3d2pA
2bufA Arginine feed-back inhibitable acetylglutamate kinase (see paper)
32% identity, 59% coverage: 45:328/478 of query aligns to 6:288/292 of 2bufA
2bufC Arginine feed-back inhibitable acetylglutamate kinase (see paper)
31% identity, 59% coverage: 45:328/478 of query aligns to 6:296/298 of 2bufC
Q9HTN2 Acetylglutamate kinase; N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; NAGK; EC 2.7.2.8 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
31% identity, 59% coverage: 45:328/478 of query aligns to 7:297/301 of Q9HTN2
Sites not aligning to the query:
2btyA Acetylglutamate kinase from thermotoga maritima complexed with its inhibitor arginine (see paper)
29% identity, 59% coverage: 50:330/478 of query aligns to 6:281/282 of 2btyA
Q9X2A4 Acetylglutamate kinase; N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; NAGK; EC 2.7.2.8 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
29% identity, 59% coverage: 50:330/478 of query aligns to 6:281/282 of Q9X2A4
2bufK Arginine feed-back inhibitable acetylglutamate kinase (see paper)
31% identity, 59% coverage: 45:328/478 of query aligns to 6:273/273 of 2bufK
2v5hB Controlling the storage of nitrogen as arginine: the complex of pii and acetylglutamate kinase from synechococcus elongatus pcc 7942 (see paper)
29% identity, 58% coverage: 50:326/478 of query aligns to 7:281/289 of 2v5hB
Q9SCL7 Acetylglutamate kinase, chloroplastic; N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AtNAGK; EC 2.7.2.8 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
29% identity, 63% coverage: 27:327/478 of query aligns to 53:346/347 of Q9SCL7
Sites not aligning to the query:
2rd5B Structural basis for the regulation of n-acetylglutamate kinase by pii in arabidopsis thaliana (see paper)
28% identity, 59% coverage: 44:327/478 of query aligns to 2:282/283 of 2rd5B
4usjB N-acetylglutamate kinase from arabidopsis thaliana in complex with pii from chlamydomonas reinhardtii (see paper)
28% identity, 58% coverage: 50:327/478 of query aligns to 4:280/281 of 4usjB
4kztA Structure mmnags bound with l-arginine (see paper)
26% identity, 57% coverage: 54:326/478 of query aligns to 15:280/431 of 4kztA
3s6hA Crystal structure of native mmnags/k (see paper)
26% identity, 57% coverage: 54:326/478 of query aligns to 19:284/436 of 3s6hA
Sites not aligning to the query:
7nlwA Crystal structure of mycobacterium tuberculosis argb in complex with 2-(5-methoxy-1h-indol-3-yl)acetonitrile
28% identity, 56% coverage: 58:326/478 of query aligns to 18:288/290 of 7nlwA
7nlyA Crystal structure of mycobacterium tuberculosis argb in complex with 2-chlorobenzimidazole.
28% identity, 56% coverage: 58:326/478 of query aligns to 20:290/293 of 7nlyA
>RR42_RS13035 FitnessBrowser__Cup4G11:RR42_RS13035
MNARTDTPADAPAPSEMDEPLPVTAPSTLPAPATGADPVERGGPDHQQFVDWLRAVAPYI
HAFRGKTFVIAFGGELVKANILDALVNDVALLHAMGMQIVLVHGSRPQVEEQLALRHVES
QFADGVRVTDNAALECAKEAAGELRLDIEAAFSQGLPNTPMAGAQLSVISGNFVTARPLG
IVDGVDYQHTGLVRKIDGESVRMSLSHGKIVLLSPLGFSPTGQAFNLSMEDVASATAIAL
KADKLVFITEVPGVQDPVGKLMPEMSLRTAIERLQNNHLPPDVSYYLEHLVKALKGGVPR
AHLIPFQLDGSVLLELFLHDGVGTMISDTDLESLREATLDDVGGILQLIAPLEQDGTLVP
RGRHLIERDIANFSVIEHDGVLFGCAALYAYPREGMAEMACLTVSSEAQGTGDGERLLKR
IERRARSLGLDRLFVLTTRTEHWFLKRGFVHANVDDLPEDKRKLYNWQRKSMVLMKKL
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory