Comparing RR42_RS15580 RR42_RS15580 aminotransferase to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
Q58097 (5-formylfuran-3-yl)methyl phosphate transaminase; 4-HFC-P:alanine aminotransferase; EC 2.6.1.108 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
35% identity, 98% coverage: 9:392/393 of query aligns to 3:368/370 of Q58097
5yhvB Crystal structure of an aminotransferase from mycobacterium tuberculosis
39% identity, 97% coverage: 13:392/393 of query aligns to 8:384/387 of 5yhvB
5yhvA Crystal structure of an aminotransferase from mycobacterium tuberculosis
39% identity, 97% coverage: 13:392/393 of query aligns to 15:391/394 of 5yhvA
P96847 Valine--pyruvate aminotransferase; Alanine--valine transaminase; EC 2.6.1.66 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
39% identity, 97% coverage: 13:392/393 of query aligns to 9:385/388 of P96847
P14909 Aspartate aminotransferase; AspAT; Transaminase A; EC 2.6.1.1 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
31% identity, 94% coverage: 22:391/393 of query aligns to 24:394/402 of P14909
Sites not aligning to the query:
1gdeA Crystal structure of pyrococcus protein a-1 e-form (see paper)
34% identity, 98% coverage: 7:390/393 of query aligns to 1:380/388 of 1gdeA
1gd9A Crystall structure of pyrococcus protein-a1 (see paper)
34% identity, 98% coverage: 7:390/393 of query aligns to 1:380/388 of 1gd9A
1o4sB Crystal structure of aspartate aminotransferase (tm1255) from thermotoga maritima at 1.90 a resolution (see paper)
32% identity, 98% coverage: 9:392/393 of query aligns to 11:382/384 of 1o4sB
P58350 Aspartate aminotransferase; AAT; AspAT; Putative 2-aminoadipate transaminase; Transaminase A; EC 2.6.1.1; EC 2.6.1.39 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
34% identity, 97% coverage: 9:388/393 of query aligns to 15:402/410 of P58350
6f35A Crystal structure of the aspartate aminotranferase from rhizobium meliloti (see paper)
33% identity, 97% coverage: 9:388/393 of query aligns to 5:392/400 of 6f35A
8wkjA The crystal structure of aspartate aminotransferases lpg0070 from legionella pneumophila (see paper)
31% identity, 91% coverage: 34:391/393 of query aligns to 30:389/391 of 8wkjA
1gc4A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with aspartate (see paper)
32% identity, 95% coverage: 20:392/393 of query aligns to 16:382/382 of 1gc4A
1gc3A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with tryptophan (see paper)
32% identity, 95% coverage: 20:392/393 of query aligns to 16:382/382 of 1gc3A
1b5oA Thermus thermophilus aspartate aminotransferase single mutant 1 (see paper)
32% identity, 93% coverage: 26:392/393 of query aligns to 22:382/382 of 1b5oA
5wmhA Arabidopsis thaliana prephenate aminotransferase (see paper)
33% identity, 97% coverage: 11:390/393 of query aligns to 5:394/399 of 5wmhA
Q56232 Aspartate/prephenate aminotransferase; AspAT / PAT; Transaminase A; EC 2.6.1.1; EC 2.6.1.78 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 3 papers)
32% identity, 93% coverage: 26:392/393 of query aligns to 22:382/385 of Q56232
Sites not aligning to the query:
1bkgA Aspartate aminotransferase from thermus thermophilus with maleate (see paper)
32% identity, 93% coverage: 26:392/393 of query aligns to 22:382/382 of 1bkgA
1bjwA Aspartate aminotransferase from thermus thermophilus (see paper)
32% identity, 93% coverage: 26:392/393 of query aligns to 22:382/382 of 1bjwA
6f77A Crystal structure of the prephenate aminotransferase from rhizobium meliloti (see paper)
32% identity, 98% coverage: 9:393/393 of query aligns to 4:396/399 of 6f77A
Q02635 Aspartate/prephenate aminotransferase; AspAT / PAT; Transaminase A; EC 2.6.1.1; EC 2.6.1.79 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
32% identity, 98% coverage: 9:393/393 of query aligns to 5:397/400 of Q02635
>RR42_RS15580 RR42_RS15580 aminotransferase
MDLQRLATASRLANIDAFHVMELAKQAAELERAGRHIIHMGIGEPDFTAAEPVVRAAEAA
MRRGVTQYTSALGIAPLREAIAGYYKTMYGIDIPARRVVVTAGASAALLLACAVLVEIGA
EVLMPDPSYPCNRHFVAAFDGRAKMIPSGPAQRFQLTAQQVETHWGEQTRGVLLASPSNP
TGTSILPDELARILKAVRTRQGFAIVDEIYQGLSYDAPPVSALSLDDDVITVNSFSKYFN
MTGWRLGWLVVPDELVGAFEKVAQNLFICASAVAQHAALACFSPEALAIYDARKAEFHRR
RDAIVPALESLGLRVPVKPDGAFYVYADCRGVNHPSAGDADALTQAMLHDAGVVLVPGQD
FGPYTASDYIRISYATSMENIEEAMARLGKFFA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory