Comparing RR42_RS16645 FitnessBrowser__Cup4G11:RR42_RS16645 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 5 hits to proteins with known functional sites (download)
2i3gA Crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase (rv1652) from mycobacterium tuberculosis in complex with NADP+. (see paper)
30% identity, 70% coverage: 90:306/309 of query aligns to 127:332/347 of 2i3gA
Sites not aligning to the query:
7npjB Crystal structure of mycobacterium tuberculosis argc in complex with 6-phenoxy-3-pyridinamine
30% identity, 70% coverage: 90:306/309 of query aligns to 124:329/344 of 7npjB
Sites not aligning to the query:
7nphC Crystal structure of mycobacterium tuberculosis argc in complex with 5-methoxy-1,3-benzoxazole-2-carboxylic acid
30% identity, 70% coverage: 90:306/309 of query aligns to 124:329/344 of 7nphC
Sites not aligning to the query:
7notA Crystal structure of mycobacterium tuberculosis argc in complex with nicotinamide adenine dinucleotide phosphate (NADP+) and 5-methoxy-3- indoleacetic acid
30% identity, 70% coverage: 90:306/309 of query aligns to 124:329/344 of 7notA
7nnrA Crystal structure of mycobacterium tuberculosis argc in complex with xanthene-9-carboxylic acid
30% identity, 70% coverage: 90:306/309 of query aligns to 124:329/344 of 7nnrA
Sites not aligning to the query:
>RR42_RS16645 FitnessBrowser__Cup4G11:RR42_RS16645
MSSPVVFIDGDQGTTGLQIHERLRDRTDLRLFTLAAAERKDPRCRAQAINACDIAILCLP
DAAAREAVDAIVNPAVRVIDASSAHRTQPDWTYGFPEMTQGQAERIANARRVTNPGCYPT
GAIGLLRPLLQAGLIPGDYPVSIHAVSGYSGRGRAGVEEHEGQGAVNAPAYQVYGLALAH
KHPPEIQLHAGLAQRPIFVPAYGAFRQGIVLTVPLALRLLPPGVDGAALHACLARHYADA
AHVRVVPLDESCALQHLDPQALNATNDMHLSVFPNAEHGHVLLSAVFDNLGKGASGAAVQ
NLDLMLTRQ
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory