Comparing RR42_RS20070 FitnessBrowser__Cup4G11:RR42_RS20070 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 10 hits to proteins with known functional sites (download)
4lhdA Crystal structure of synechocystis sp. Pcc 6803 glycine decarboxylase (p-protein), holo form with pyridoxal-5'-phosphate and glycine, closed flexible loop (see paper)
60% identity, 98% coverage: 17:967/973 of query aligns to 6:952/952 of 4lhdA
Q94B78 Glycine dehydrogenase (decarboxylating) 1, mitochondrial; Glycine cleavage system P protein 1; Glycine decarboxylase 1; Glycine decarboxylase P-protein 1; AtGLDP1; Glycine dehydrogenase (aminomethyl-transferring) 1; EC 1.4.4.2 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
56% identity, 98% coverage: 20:969/973 of query aligns to 73:1029/1037 of Q94B78
6i35A Crystal structure of human glycine decarboxylase (p-protein) bound with pyridoxyl-glycine-5'-monophosphate
53% identity, 97% coverage: 20:967/973 of query aligns to 9:953/953 of 6i35A
6i34B Crystal structure of neanderthal glycine decarboxylase (p-protein)
53% identity, 97% coverage: 20:966/973 of query aligns to 7:954/954 of 6i34B
6i33A Crystal structure of human glycine decarboxylase (p-protein)
53% identity, 97% coverage: 20:967/973 of query aligns to 9:950/950 of 6i33A
P15505 Glycine dehydrogenase (decarboxylating), mitochondrial; Glycine cleavage system P protein; Glycine decarboxylase; Glycine dehydrogenase (aminomethyl-transferring); EC 1.4.4.2 from Gallus gallus (Chicken) (see paper)
52% identity, 99% coverage: 11:970/973 of query aligns to 38:992/1004 of P15505
6i33B Crystal structure of human glycine decarboxylase (p-protein)
52% identity, 97% coverage: 20:966/973 of query aligns to 7:925/925 of 6i33B
1wyuB Crystal structure of glycine decarboxylase (p-protein) of the glycine cleavage system, in holo form (see paper)
39% identity, 44% coverage: 496:921/973 of query aligns to 46:457/473 of 1wyuB
1wyvA Crystal structure of glycine decarboxylase (p-protein) of the glycine cleavage system, in inhibitor-bound form (see paper)
39% identity, 39% coverage: 76:452/973 of query aligns to 44:431/437 of 1wyvA
1wyuA Crystal structure of glycine decarboxylase (p-protein) of the glycine cleavage system, in holo form (see paper)
39% identity, 39% coverage: 76:452/973 of query aligns to 44:431/437 of 1wyuA
>RR42_RS20070 FitnessBrowser__Cup4G11:RR42_RS20070
MNAPLPMTAAQVARPTLAELEARDAFASRHIGPDAAEQQHMLKVLGYDNRAALIDAVIPA
AIRRRDGMPLGEFTAPLTEEAALAKLRGLASKNRVLKSFIGQGYYNTLTPGVVLRNIFEN
PAWYTAYTPYQPEISQGRLEAMLNFQQMVTDLTGLDIANASMLDEGTAAAEAMTLLQRVN
KHASTTFYVADDVLPQTLEVVRTRALPLGIEVKVGPAAEAAGAHAFGVLLQYPGVNGDVA
DYRAIADAVHAAGGLVVAAADLLALTLIAAPGEWGADVAVGNSQRFGVPLGFGGPHAGYM
AVKDAFKRSMPGRLVGVTIDAQGNKAYRLALQTREQHIRREKATSNICTAQVLLAVMASM
YAVYHGPQGLKRIAQRVHRLTATLAGGLEQLGYARTNATFFDTLTLETGFNTEALHASAT
ARGINLRHAGATRIGISLDETASREDVVALLEIFAHGKPVPGFDALEAAAQDAFPAGLAR
QSAYLTHPVFNTHHAEHEMLRYLRMLADKDLALDRTMIPLGSCTMKLNATSEMIPVTWPE
FSKIHPFAPLDQTVGYREMIDQLEAMLCAATGYAAVSLQPNAGSQGEYAGLLIIHAYHAS
RGESHRDICLIPSSAHGTNPASAQMAGMKVVVVACDENGNVDLEDLAKKAEQHSKNLAAI
MITYPSTHGVFEQGVQQICHIVHKHGGQVYVDGANMNAMVGTAAPGQFGGDVSHLNLHKT
FCIPHGGGGPGVGPVAVGAHLADFLPNQDSVGYRRDDQGIGGVSAAPFGSASILPISWMY
IAMMGSAGLTAATENAILAANYVARRLSPHFPVLYTGQHGLVAHECILDVRALQKTTGIS
NEDVAKRLMDYGFHAPTMSFPVPGTLMIEPTESEALHELDRFIDAMIAIRAEIARVEDGT
FDREDNPLKNAPHTAAVITADVWEHKYTRQEAAYPVAALRTQKYWPPVGRADNVYGDRNL
FCACVPMSEYTEE
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory