Comparing RR42_RS21365 FitnessBrowser__Cup4G11:RR42_RS21365 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P0AAH4 Putrescine export system ATP-binding protein SapD from Escherichia coli (strain K12) (see paper)
38% identity, 47% coverage: 7:264/545 of query aligns to 1:263/330 of P0AAH4
Q8RDH4 Dipeptide transport ATP-binding protein DppD; EC 7.4.2.9 from Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis) (see paper)
42% identity, 43% coverage: 32:263/545 of query aligns to 27:258/326 of Q8RDH4
Sites not aligning to the query:
4fwiB Crystal structure of the nucleotide-binding domain of a dipeptide abc transporter (see paper)
42% identity, 43% coverage: 32:263/545 of query aligns to 26:257/310 of 4fwiB
Sites not aligning to the query:
P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 3 papers)
35% identity, 46% coverage: 279:530/545 of query aligns to 1:243/343 of P30750
Sites not aligning to the query:
6cvlD Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
35% identity, 46% coverage: 279:530/545 of query aligns to 2:244/344 of 6cvlD
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form (see paper)
35% identity, 46% coverage: 279:530/545 of query aligns to 2:244/344 of 3tuzC
Sites not aligning to the query:
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form (see paper)
35% identity, 46% coverage: 279:530/545 of query aligns to 2:244/344 of 3tuiC
3c4jA Abc protein artp in complex with atp-gamma-s
33% identity, 46% coverage: 279:531/545 of query aligns to 3:241/242 of 3c4jA
3c41J Abc protein artp in complex with amp-pnp/mg2+
33% identity, 46% coverage: 279:531/545 of query aligns to 3:241/242 of 3c41J
2olkA Abc protein artp in complex with adp-beta-s
33% identity, 46% coverage: 279:531/545 of query aligns to 3:241/242 of 2olkA
2oljA Abc protein artp in complex with adp/mg2+
33% identity, 46% coverage: 279:531/545 of query aligns to 3:241/242 of 2oljA
7z15I E. Coli c-p lyase bound to a phnk/phnl dual abc dimer and adp + pi (see paper)
37% identity, 47% coverage: 279:535/545 of query aligns to 3:251/253 of 7z15I
7z18I E. Coli c-p lyase bound to a phnk abc dimer and atp (see paper)
37% identity, 46% coverage: 279:531/545 of query aligns to 3:247/250 of 7z18I
7z16I E. Coli c-p lyase bound to phnk/phnl dual abc dimer with amppnp and phnk e171q mutation (see paper)
36% identity, 46% coverage: 279:531/545 of query aligns to 3:247/250 of 7z16I
4u00A Crystal structure of ttha1159 in complex with adp (see paper)
33% identity, 46% coverage: 279:531/545 of query aligns to 2:239/241 of 4u00A
P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 3 papers)
33% identity, 43% coverage: 296:531/545 of query aligns to 27:251/378 of P69874
Sites not aligning to the query:
7ahhC Opua inhibited inward-facing, sbd docked (see paper)
33% identity, 43% coverage: 29:260/545 of query aligns to 42:263/382 of 7ahhC
Sites not aligning to the query:
7aheC Opua inhibited inward facing (see paper)
33% identity, 43% coverage: 29:260/545 of query aligns to 42:263/382 of 7aheC
Sites not aligning to the query:
1g291 Malk (see paper)
34% identity, 43% coverage: 28:264/545 of query aligns to 18:244/372 of 1g291
Sites not aligning to the query:
7ahdC Opua (e190q) occluded (see paper)
33% identity, 42% coverage: 29:257/545 of query aligns to 42:260/260 of 7ahdC
Sites not aligning to the query:
>RR42_RS21365 FitnessBrowser__Cup4G11:RR42_RS21365
MQAQDKLPLLSVRELTIALPAGGDRAHAVKEVSYDLHAGEILCIVGESGSGKSMSANAIM
GLLPPYLKPQGGQILFQGKDLLTQDEQTLLSMRGKAMAMVFQEPLSALNPVMTVGDQIAE
VMRVHDAYPGEARTKRVLELLEFVGLPDPATLIHSYPFRLSGGQRQRVVIAMALALEPAL
LIADEPTTALDVTTQAQILALIRRIQADKGMGVMFVTHDFGVVAEIADRVAVMERGVLVE
VGPVQQVLNHPQHPYTRRLIGAVPHGRAKARDQQAAETVLEVRDLRKTYSSGGGLFSKKR
VVNAVDGVSFSVRRGQTLGIVGESGSGKSTIGKCLLKLTDIDGGELLFDGQDIARLTERQ
FRPLRSDVQMIFQDPFASLNPRHTVGRIITDGPIANGAALAQAQARGRELLQLVGLEPSA
FDRYPNQFSGGQRQRIGIARALALDPKLLVADESVSALDVSVQAQVLQLLADLQKRLNIG
LIFITHDLRVAAQICHHVIVMHKGRVVESGPPDQIFDAPQHAYTQRLIAAIPGKEWDPTL
IRAAA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory