Comparing RR42_RS27405 FitnessBrowser__Cup4G11:RR42_RS27405 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
6g4dB Crystal structure of the omega transaminase from pseudomonas jessenii in complex with plp (see paper)
55% identity, 99% coverage: 5:446/448 of query aligns to 1:442/453 of 6g4dB
6g4fA Crystal structure of the omega transaminase from pseudomonas jessenii in complex with pmp (see paper)
55% identity, 99% coverage: 5:446/448 of query aligns to 1:442/451 of 6g4fA
6g4eA Crystal structure of the omega transaminase from pseudomonas jessenii in complex with plp and 6-aminohexanoate (6-aca) (see paper)
55% identity, 99% coverage: 5:446/448 of query aligns to 1:442/451 of 6g4eA
5ghgB Transaminase w58l with smba
55% identity, 98% coverage: 6:443/448 of query aligns to 3:421/433 of 5ghgB
Q94CE5 Gamma-aminobutyrate transaminase POP2, mitochondrial; AtGABA-T; Gamma-aminobutyric acid aminotransferase 1; Protein HEXENAL RESPONSE 1; Protein POLLEN-PISTIL INCOMPATIBILITY 2; AtPOP2; EC 2.6.1.96 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
50% identity, 97% coverage: 16:448/448 of query aligns to 56:490/504 of Q94CE5
D6R3B6 Vanillin aminotransferase; Putative aminotransferase; pAMT; EC 2.6.1.119 from Capsicum frutescens (Cayenne pepper) (Tabasco pepper) (see paper)
50% identity, 96% coverage: 16:446/448 of query aligns to 14:444/459 of D6R3B6
5kr6B Directed evolution of transaminases by ancestral reconstruction. Using old proteins for new chemistries
48% identity, 96% coverage: 11:438/448 of query aligns to 13:445/460 of 5kr6B
5kr5A Directed evolution of transaminases by ancestral reconstruction. Using old proteins for new chemistries
49% identity, 96% coverage: 11:440/448 of query aligns to 9:443/455 of 5kr5A
Sites not aligning to the query:
5kr3A Directed evolution of transaminases by ancestral reconstruction. Using old proteins for new chemistries
47% identity, 100% coverage: 1:446/448 of query aligns to 2:450/458 of 5kr3A
4e3qA Pmp-bound form of aminotransferase crystal structure from vibrio fluvialis (see paper)
44% identity, 96% coverage: 16:446/448 of query aligns to 15:444/452 of 4e3qA
4grxC Structure of an omega-aminotransferase from paracoccus denitrificans (see paper)
45% identity, 96% coverage: 16:446/448 of query aligns to 12:441/449 of 4grxC
5kquC Directed evolution of transaminases by ancestral reconstruction. Using old proteins for new chemistries
46% identity, 98% coverage: 1:438/448 of query aligns to 1:443/459 of 5kquC
6gwiB The crystal structure of halomonas elongata amino-transferase (see paper)
43% identity, 97% coverage: 11:446/448 of query aligns to 10:442/450 of 6gwiB
3fcrA Crystal structure of putative aminotransferase (yp_614685.1) from silicibacter sp. Tm1040 at 1.80 a resolution
40% identity, 100% coverage: 1:448/448 of query aligns to 2:455/458 of 3fcrA
3gjuA Crystal structure of a putative aminotransferase (mll7127) from mesorhizobium loti maff303099 at 1.55 a resolution
41% identity, 96% coverage: 7:434/448 of query aligns to 9:441/458 of 3gjuA
7qx0B Transaminase structure of plurienzyme (tr2e2) in complex with plp (see paper)
43% identity, 97% coverage: 11:446/448 of query aligns to 9:435/443 of 7qx0B
7qx3A Structure of the transaminase tr2e2 with eos (see paper)
44% identity, 93% coverage: 32:446/448 of query aligns to 3:414/422 of 7qx3A
6io1B Crystal structure of a novel thermostable (s)-enantioselective omega- transaminase from thermomicrobium roseum (see paper)
43% identity, 96% coverage: 5:434/448 of query aligns to 6:431/448 of 6io1B
7ypmA Crystal structure of transaminase cc1012 complexed with plp and l- alanine (see paper)
43% identity, 93% coverage: 29:446/448 of query aligns to 29:444/454 of 7ypmA
7q9xAAA Probable aminotransferase
42% identity, 97% coverage: 11:446/448 of query aligns to 10:442/455 of 7q9xAAA
>RR42_RS27405 FitnessBrowser__Cup4G11:RR42_RS27405
MPSHAALAADDIAAHLHPFTNLAAHPGVGPLVITKGDGIYVEDDQGKRYLEGMSGLWCSS
LGFSHARVIEAGVEAMRTLPYYHTFNHRSNPAAIMLAEKLVAMAPVPMSKVFFANSGSEA
NDTAVKLVWYYHNAIGKPDKKKIIARTNAYHGVTVAAASLSGLQANHRDFDLPIDRILRA
GCPHHYRYGAPGESEAAFASRLAQELEALIQAQGPDTIGAFIAEPVMGAGGVIVPPATYF
AEIQAVLRRHDILLIADEVICGFGRTGAMFGSTTYGMRPDILTCAKALSSGYMPISAVMV
SEKVHAAIAANSGKIGTFGHGFTYSGHPVTTAVALETLRVYEDDRILDHVNAIAPRFQQA
LQAYAGRALVGEVRGVGLLGAIELAAEPAARRAFDPALKAGPRLAQLAQEQGLIVRAMGD
TIAFCPPLIITEAQIGELFARFERAMVA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory