Comparing RR42_RS28295 FitnessBrowser__Cup4G11:RR42_RS28295 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
7bxsA 2-amino-3-ketobutyrate coa ligase from cupriavidus necator glycine binding form
78% identity, 100% coverage: 1:399/400 of query aligns to 1:399/399 of 7bxsA
7bxrA 2-amino-3-ketobutyrate coa ligase from cupriavidus necator 3- hydroxynorvaline binding form
78% identity, 100% coverage: 1:399/400 of query aligns to 1:399/399 of 7bxrA
7bxqA 2-amino-3-ketobutyrate coa ligase from cupriavidus necator l-threonine binding form
78% identity, 100% coverage: 1:399/400 of query aligns to 1:399/399 of 7bxqA
1fc4A 2-amino-3-ketobutyrate coa ligase (see paper)
60% identity, 98% coverage: 7:399/400 of query aligns to 8:400/401 of 1fc4A
P0AB77 2-amino-3-ketobutyrate coenzyme A ligase; AKB ligase; Glycine acetyltransferase; EC 2.3.1.29 from Escherichia coli (strain K12) (see paper)
60% identity, 98% coverage: 7:399/400 of query aligns to 5:397/398 of P0AB77
3tqxA Structure of the 2-amino-3-ketobutyrate coenzyme a ligase (kbl) from coxiella burnetii (see paper)
60% identity, 98% coverage: 9:399/400 of query aligns to 6:396/396 of 3tqxA
7v58B Structural insights into the substrate selectivity of acyl-coa transferase (see paper)
57% identity, 99% coverage: 4:400/400 of query aligns to 4:400/400 of 7v58B
Q0P5L8 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial; AKB ligase; Aminoacetone synthase; Glycine acetyltransferase; EC 2.3.1.29 from Bos taurus (Bovine) (see paper)
55% identity, 96% coverage: 11:394/400 of query aligns to 31:413/419 of Q0P5L8
Sites not aligning to the query:
7poaA An irreversible, promiscuous and highly thermostable claisen- condensation biocatalyst drives the synthesis of substituted pyrroles
44% identity, 98% coverage: 9:400/400 of query aligns to 10:398/398 of 7poaA
8h29A Serine palmitoyltransferase from sphingobacterium multivorum complexed with l-threonine (see paper)
36% identity, 93% coverage: 15:387/400 of query aligns to 15:383/394 of 8h29A
8h21A Serine palmitoyltransferase from sphingobacterium multivorum complexed with l-alanine (see paper)
36% identity, 93% coverage: 15:387/400 of query aligns to 15:383/394 of 8h21A
8h20A Serine palmitoyltransferase from sphingobacterium multivorum complexed with glycine (see paper)
36% identity, 93% coverage: 15:387/400 of query aligns to 15:383/394 of 8h20A
8h1yA Serine palmitoyltransferase from sphingobacterium multivorum complexed with l-homoserine (see paper)
36% identity, 93% coverage: 15:387/400 of query aligns to 15:383/394 of 8h1yA
8h1qA Serine palmitoyltransferase from sphingobacterium multivorum complexed with l-serine (see paper)
36% identity, 93% coverage: 15:387/400 of query aligns to 15:383/394 of 8h1qA
8guhA Serine palmitoyltransferase from sphingobacterium multivorum complexed with tris (see paper)
36% identity, 93% coverage: 15:387/400 of query aligns to 15:383/394 of 8guhA
3a2bA Crystal structure of serine palmitoyltransferase from sphingobacterium multivorum with substrate l-serine (see paper)
36% identity, 93% coverage: 15:387/400 of query aligns to 15:383/392 of 3a2bA
Q5W264 4-hydroxy-2,2'-bipyrrole-5-methanol synthase PigH; HBM synthase; Aminotransferase PigH; EC 2.3.2.- from Serratia sp. (strain ATCC 39006) (see paper)
36% identity, 90% coverage: 40:398/400 of query aligns to 281:636/653 of Q5W264
Sites not aligning to the query:
P18079 5-aminolevulinate synthase; 5-aminolevulinic acid synthase; Delta-ALA synthase; Delta-aminolevulinate synthase; EC 2.3.1.37 from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) (see paper)
35% identity, 96% coverage: 10:391/400 of query aligns to 6:395/409 of P18079
Q93UV0 Serine palmitoyltransferase; SPT; EC 2.3.1.50 from Sphingomonas paucimobilis (Pseudomonas paucimobilis) (see 4 papers)
35% identity, 93% coverage: 30:399/400 of query aligns to 54:419/420 of Q93UV0
Sites not aligning to the query:
2xbnA Inhibition of the plp-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation (see paper)
35% identity, 93% coverage: 30:399/400 of query aligns to 33:398/398 of 2xbnA
>RR42_RS28295 FitnessBrowser__Cup4G11:RR42_RS28295
MPTTDAFYAAIRQELESIEQAGLFKTERVIASPQGSLIRTTDGKEVINLCANNYLGLSSH
PEVVEAAHRALGERGFGLSSVRFICGTQDLHKSLEARLASFLGTEDTILYGSAFDANGGL
FETLLGSDDAVISDELNHASIIDGIRLCKAKRFRYKNNDLEDLREQLKAADAAGARFKLV
FTDGVFSMDGTIARLDEIREICDEFGALLGIDECHATGFLGQRGRGSHEHRGIFGKVDII
TGTLGKALGGASGGFTSGRKEVVALLRQRSRPYLFSNTVAPCIVGATLKVLDLLEADTTL
RDKLERNARYFRGKLGTLGFDVKPGDHPIIPVMVYDAEKAQRLSRRLLELGVYVIGFFYP
VVPRGQARIRVQISALHDSAELDQALEAFEIAGKELGIIQ
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory