Comparing SM_b20301 FitnessBrowser__Smeli:SM_b20301 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 18 hits to proteins with known functional sites (download)
7cdyA Crystal structure of glucose dehydrogenase
47% identity, 89% coverage: 38:372/376 of query aligns to 2:343/346 of 7cdyA
P75804 Aldose sugar dehydrogenase YliI; Asd; Soluble aldose sugar dehydrogenase YliI; EC 1.1.5.- from Escherichia coli (strain K12) (see paper)
46% identity, 90% coverage: 37:376/376 of query aligns to 25:371/371 of P75804
2g8sA Crystal structure of the soluble aldose sugar dehydrogenase (asd) from escherichia coli in the apo-form (see paper)
46% identity, 90% coverage: 37:374/376 of query aligns to 3:347/348 of 2g8sA
7cgzA Glucose dehydrogenase
46% identity, 89% coverage: 38:372/376 of query aligns to 2:318/321 of 7cgzA
2ismB Crystal structure of the putative oxidoreductase (glucose dehydrogenase) (ttha0570) from thermus theromophilus hb8
35% identity, 88% coverage: 37:368/376 of query aligns to 2:319/333 of 2ismB
3a9hA Crystal structure of pqq-dependent sugar dehydrogenase holo-form (see paper)
37% identity, 88% coverage: 38:368/376 of query aligns to 5:320/338 of 3a9hA
3a9gA Crystal structure of pqq-dependent sugar dehydrogenase apo-form (see paper)
37% identity, 88% coverage: 38:368/376 of query aligns to 5:320/338 of 3a9gA
3dasA Structure of the pqq-bound form of aldose sugar dehydrogenase (adh) from streptomyces coelicolor
34% identity, 74% coverage: 39:316/376 of query aligns to 11:272/334 of 3dasA
Sites not aligning to the query:
1cq1A Soluble quinoprotein glucose dehydrogenase from acinetobacter calcoaceticus in complex with pqqh2 and glucose (see paper)
26% identity, 88% coverage: 40:371/376 of query aligns to 20:425/444 of 1cq1A
1c9uA Crystal structure of the soluble quinoprotein glucose dehydrogenase in complex with pqq (see paper)
26% identity, 88% coverage: 40:371/376 of query aligns to 20:425/444 of 1c9uA
P13650 Quinoprotein glucose dehydrogenase B; Glucose dehydrogenase B [pyrroloquinoline-quinone]; Soluble glucose dehydrogenase; s-GDH; EC 1.1.5.2 from Acinetobacter calcoaceticus (see paper)
26% identity, 88% coverage: 40:371/376 of query aligns to 44:455/478 of P13650
1cruA Soluble quinoprotein glucose dehydrogenase from acinetobacter calcoaceticus in complex with pqq and methylhydrazine (see paper)
26% identity, 88% coverage: 40:371/376 of query aligns to 20:429/448 of 1cruA
5minB Apo form of the soluble pqq-dependent glucose dehydrogenase from acinetobacter calcoaceticus
26% identity, 88% coverage: 40:371/376 of query aligns to 20:431/453 of 5minB
2wfxB Crystal structure of the complex between human hedgehog-interacting protein hip and sonic hedgehog in the presence of calcium (see paper)
26% identity, 53% coverage: 38:236/376 of query aligns to 4:219/417 of 2wfxB
Sites not aligning to the query:
Q96QV1 Hedgehog-interacting protein; HHIP; HIP from Homo sapiens (Human) (see 3 papers)
26% identity, 53% coverage: 38:236/376 of query aligns to 218:444/700 of Q96QV1
Sites not aligning to the query:
7pgnB Hhp-c in complex with glycosaminoglycan mimic sos (see paper)
26% identity, 49% coverage: 38:221/376 of query aligns to 5:208/438 of 7pgnB
Sites not aligning to the query:
7pgnA Hhp-c in complex with glycosaminoglycan mimic sos (see paper)
26% identity, 49% coverage: 38:221/376 of query aligns to 6:209/437 of 7pgnA
Sites not aligning to the query:
7pgmB Hhip-c in complex with heparin (see paper)
24% identity, 54% coverage: 38:239/376 of query aligns to 5:221/427 of 7pgmB
Sites not aligning to the query:
>SM_b20301 FitnessBrowser__Smeli:SM_b20301
MRAAVFLALAAAVAVARHETATAQDSPRMLDTESGPVSVEVFAGGLEHPWGAALLPDGDM
LVTERPGRLRLVSAEGAVGEPIEGVPDVFAQGQGGLLDVALDPDFATNRTVYLSFAEERE
GGAATSVGRGRLNDDATALSDFKIIFRQEPAASGENHFGSRLAFAPDGKLFITLGERFDM
QEAQDPANHLGTIVRLNPDGSIPDDNPFVGREGADEIWSYGHRNVQSAAIHPETDVLWTA
EMGPMGGDELNIPEAGKNYGWPAVSWGRHYTGERIPDPPSRPEFAGSIHSWTPVISPSGM
MFYTGDLFADWRGDLLIGGLSVGGIVRVQTDGQKVTGEEVLSLEARIRDLLQASDGSVLA
LIDAASGRILRLRPAN
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory