Comparing SM_b20446 FitnessBrowser__Smeli:SM_b20446 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 4 hits to proteins with known functional sites (download)
4eayA Crystal structures of mannonate dehydratase from escherichia coli strain k12 complexed with d-mannonate (see paper)
53% identity, 99% coverage: 1:396/402 of query aligns to 3:395/395 of 4eayA
4eacC Crystal structure of mannonate dehydratase from escherichia coli strain k12 (see paper)
53% identity, 99% coverage: 1:396/402 of query aligns to 3:395/396 of 4eacC
3dbnA Crystal structure of the streptoccocus suis serotype2 d- mannonate dehydratase in complex with its substrate (see paper)
33% identity, 100% coverage: 1:401/402 of query aligns to 3:348/349 of 3dbnA
3bdkA Crystal structure of streptococcus suis mannonate dehydratase complexed with substrate analogue
33% identity, 100% coverage: 1:401/402 of query aligns to 3:348/349 of 3bdkA
>SM_b20446 FitnessBrowser__Smeli:SM_b20446
MRHTWRWFGPVDRVSVQDAAQAGAHGIVSALHHIPTGDVWPVDEIGKRQEEVRAGGLEWE
VVESVPVSECIKTQTGPWREHVANWQETLRRLSAAGIRTVCYNFMPVLDWTRTDLRWTAR
HGAKAMRFDRIDFAAFDIHLLERPAAHEDYDTATREAAERRFREMTEERRLALSRNIGAG
LPGSADGYSLPQLREHLRTYDGVSREKLQRHLVEFLAEVAPVAERTGINICAHPDDPPWA
LLGLPRILSNAEDYAFMLREVDSPANGVTLCTGSLGALAANDLPAMTRQFASRIHFVHLR
NVLREEVRTPCSFYEDEHLEGDTDMVAVIAELLQEEQRRRAAGRVDHQIPMRPDHGQEIL
DDLSRGAQPGYPAIGRLKGLAELRGIERALSHATYGLSAATR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory