Comparing SMa0216 FitnessBrowser__Smeli:SMa0216 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P04983 Ribose import ATP-binding protein RbsA; EC 7.5.2.7 from Escherichia coli (strain K12) (see paper)
35% identity, 97% coverage: 7:244/246 of query aligns to 4:238/501 of P04983
4ymuJ Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
32% identity, 88% coverage: 10:226/246 of query aligns to 4:215/240 of 4ymuJ
1vciA Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
31% identity, 88% coverage: 8:223/246 of query aligns to 7:205/353 of 1vciA
P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 3 papers)
33% identity, 88% coverage: 7:223/246 of query aligns to 1:217/343 of P30750
Sites not aligning to the query:
6cvlD Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
33% identity, 89% coverage: 6:223/246 of query aligns to 1:218/344 of 6cvlD
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form (see paper)
33% identity, 89% coverage: 6:223/246 of query aligns to 1:218/344 of 3tuzC
Sites not aligning to the query:
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form (see paper)
33% identity, 89% coverage: 6:223/246 of query aligns to 1:218/344 of 3tuiC
3c4jA Abc protein artp in complex with atp-gamma-s
31% identity, 89% coverage: 6:223/246 of query aligns to 2:214/242 of 3c4jA
3c41J Abc protein artp in complex with amp-pnp/mg2+
31% identity, 89% coverage: 6:223/246 of query aligns to 2:214/242 of 3c41J
2olkA Abc protein artp in complex with adp-beta-s
31% identity, 89% coverage: 6:223/246 of query aligns to 2:214/242 of 2olkA
2oljA Abc protein artp in complex with adp/mg2+
31% identity, 89% coverage: 6:223/246 of query aligns to 2:214/242 of 2oljA
2d62A Crystal structure of multiple sugar binding transport atp- binding protein
30% identity, 88% coverage: 8:223/246 of query aligns to 7:219/375 of 2d62A
5l22B Prtd t1ss abc transporter (see paper)
33% identity, 90% coverage: 18:239/246 of query aligns to 325:539/540 of 5l22B
Sites not aligning to the query:
1g291 Malk (see paper)
29% identity, 88% coverage: 8:224/246 of query aligns to 4:217/372 of 1g291
Sites not aligning to the query:
4u00A Crystal structure of ttha1159 in complex with adp (see paper)
29% identity, 89% coverage: 7:226/246 of query aligns to 2:215/241 of 4u00A
4yerA Crystal structure of an abc transporter atp-binding protein (tm_1403) from thermotoga maritima msb8 at 2.35 a resolution
29% identity, 89% coverage: 6:223/246 of query aligns to 3:212/285 of 4yerA
4q9iA P-glycoprotein cocrystallised with qz-ala (see paper)
34% identity, 81% coverage: 8:207/246 of query aligns to 359:556/1184 of 4q9iA
Sites not aligning to the query:
1g6hA Crystal structure of the adp conformation of mj1267, an atp-binding cassette of an abc transporter (see paper)
27% identity, 89% coverage: 4:223/246 of query aligns to 1:226/254 of 1g6hA
4m1mA Corrected structure of mouse p-glycoprotein (see paper)
34% identity, 81% coverage: 8:207/246 of query aligns to 359:556/1188 of 4m1mA
Sites not aligning to the query:
4xwkA P-glycoprotein co-crystallized with bde-100 (see paper)
34% identity, 81% coverage: 8:207/246 of query aligns to 359:556/1182 of 4xwkA
Sites not aligning to the query:
>SMa0216 FitnessBrowser__Smeli:SMa0216
MMSTPNLLELHNISKSFGALTALRNLSFHIGEGEVVGLLGDNGAGKSTTVNLISGIHKPT
DGYLSVDGKKTTFSCRSDSADAGIETIYQHTALVDSLSITRNIFMGRELTDRFGFLRQRE
MRDIAMEVLQNAVHISGIDSPDTLVGNLSGGQKQAVAIARAVYFKKRVLLLDEPTSALSV
RETEALLNQVLKLKAENVSSVLVTHNLYHAYQVCDRFVIMSHGTKVFDVQKADTTISQLT
EYVVLT
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory