Comparing SMa0483 FitnessBrowser__Smeli:SMa0483 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
Q6NPM8 Bifunctional phosphatase IMPL2, chloroplastic; Histidinol-phosphatase; Histidinol-phosphate phosphatase; HPP; Inositol-phosphate phosphatase; L-galactose 1-phosphate phosphatase; Protein HISTIDINE BIOSYNTHESIS 7; Protein MYO-INOSITOL MONOPHOSPHATASE-LIKE 2; EC 3.1.3.15; EC 3.1.3.25; EC 3.1.3.93 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
37% identity, 94% coverage: 19:307/308 of query aligns to 45:343/346 of Q6NPM8
5eq9B Crystal structure of medicago truncatula histidinol-phosphate phosphatase (mthpp) in complex with l-histidinol phosphate and mg2+ (see paper)
39% identity, 79% coverage: 66:307/308 of query aligns to 6:258/260 of 5eq9B
5eq8A Crystal structure of medicago truncatula histidinol-phosphate phosphatase (mthpp) in complex with l-histidinol (see paper)
38% identity, 79% coverage: 64:307/308 of query aligns to 3:257/259 of 5eq8A
5t3jA Histidinol phosphate phosphatase(hpp) soaked with selenourea for 10 min (see paper)
38% identity, 79% coverage: 64:307/308 of query aligns to 6:255/257 of 5t3jA
Sites not aligning to the query:
Q9M8S8 Inositol-phosphate phosphatase; L-galactose 1-phosphate phosphatase; Myo-inositol monophosphatase; EC 3.1.3.25; EC 3.1.3.93 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
33% identity, 68% coverage: 87:296/308 of query aligns to 38:257/271 of Q9M8S8
Q9K4B1 Histidinol-phosphatase; HolPase; Histidinol-phosphate phosphatase; EC 3.1.3.15 from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
35% identity, 64% coverage: 87:282/308 of query aligns to 36:240/266 of Q9K4B1
P95189 Histidinol-phosphatase; HolPase; Histidinol-phosphate phosphatase; EC 3.1.3.15 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
36% identity, 72% coverage: 87:307/308 of query aligns to 34:257/260 of P95189
5yhtA Crystal structure of a phosphatase from mycobacterium tuberculosis in complex with its substrate (see paper)
36% identity, 72% coverage: 87:307/308 of query aligns to 31:254/255 of 5yhtA
5zonA Histidinol phosphate phosphatase from mycobacterium tuberculosis (see paper)
36% identity, 72% coverage: 87:307/308 of query aligns to 32:255/256 of 5zonA
Q19420 Inositol monophosphatase ttx-7; IMP; IMPase; Abnormal thermotaxis protein 7; D-galactose 1-phosphate phosphatase; Inositol-1(or 4)-monophosphatase; EC 3.1.3.25; EC 3.1.3.94 from Caenorhabditis elegans (see paper)
31% identity, 68% coverage: 88:295/308 of query aligns to 44:266/285 of Q19420
2p3nA Thermotoga maritima impase tm1415 (see paper)
28% identity, 68% coverage: 93:300/308 of query aligns to 38:239/256 of 2p3nA
O33832 Fructose-1,6-bisphosphatase/inositol-1-monophosphatase; FBPase/IMPase; Inositol-1-phosphatase; I-1-Pase; EC 3.1.3.11; EC 3.1.3.25 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
28% identity, 68% coverage: 93:300/308 of query aligns to 38:239/256 of O33832
6tqoT Rrn anti-termination complex (see paper)
28% identity, 64% coverage: 85:280/308 of query aligns to 19:224/255 of 6tqoT
2qflA Structure of suhb: inositol monophosphatase and extragenic suppressor from e. Coli (see paper)
28% identity, 64% coverage: 83:280/308 of query aligns to 30:232/262 of 2qflA
P0ADG4 Nus factor SuhB; Inositol-1-monophosphatase; I-1-Pase; IMPase; Inositol-1-phosphatase; EC 3.1.3.25 from Escherichia coli (strain K12) (see 5 papers)
28% identity, 64% coverage: 83:280/308 of query aligns to 30:232/267 of P0ADG4
Sites not aligning to the query:
6ib8B Structure of a complex of suhb and nusa ar2 domain (see paper)
28% identity, 64% coverage: 83:280/308 of query aligns to 34:236/270 of 6ib8B
O14732 Inositol monophosphatase 2; IMP 2; IMPase 2; Inositol-1(or 4)-monophosphatase 2; Myo-inositol monophosphatase A2; EC 3.1.3.25 from Homo sapiens (Human) (see 2 papers)
27% identity, 81% coverage: 48:298/308 of query aligns to 8:269/288 of O14732
4as5A Structure of mouse inositol monophosphatase 1 (see paper)
26% identity, 82% coverage: 55:306/308 of query aligns to 2:264/274 of 4as5A
P20456 Inositol monophosphatase 1; IMP 1; IMPase 1; D-galactose 1-phosphate phosphatase; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; EC 3.1.3.25; EC 3.1.3.94 from Bos taurus (Bovine) (see paper)
25% identity, 82% coverage: 55:306/308 of query aligns to 4:266/277 of P20456
2bjiA High resolution structure of myo-inositol monophosphatase, the target of lithium therapy (see paper)
25% identity, 82% coverage: 55:306/308 of query aligns to 2:264/274 of 2bjiA
>SMa0483 FitnessBrowser__Smeli:SMa0483
MPPMQFLRARRSPADNRLSIGIAIPTCRRWTCSPAGGTVPPTTIKGVQNSMFDPPLGEFA
SFAHDIADLARQTISSAAGVRREPIAKSDASPVTETDRAVEKCLRERIADHFPDHGVLGE
EFGAEGLGNEFVWVIDPIDGTKAFVAGLPVYGTLISLTRGGTPILGLIDNPMTGDRWLGV
SGQPTTLNNVPIRTASTTALATAFIANGNPDAFSPADKSRVESLRRITRWCVYGGSCIAY
GRVADGSVDISIDGGLDPYDYCALVPVITGAGGCITDWQGRPLTLNSGGLCVATATDLLH
RHVLEILA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory