Comparing SMa0485 FitnessBrowser__Smeli:SMa0485 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 5 hits to proteins with known functional sites (download)
4f4fA X-ray crystal structure of plp bound threonine synthase from brucella melitensis
40% identity, 91% coverage: 2:442/484 of query aligns to 2:432/464 of 4f4fA
1kl7A Crystal structure of threonine synthase from yeast (see paper)
38% identity, 87% coverage: 14:435/484 of query aligns to 18:460/509 of 1kl7A
Q42598 Threonine synthase; TS; EC 4.2.3.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
36% identity, 90% coverage: 2:435/484 of query aligns to 5:463/514 of Q42598
8g1yA Crystal structure of the threonine synthase from streptococcus pneumoniae in complex with pyridoxal 5-phosphate.
34% identity, 89% coverage: 4:435/484 of query aligns to 7:440/496 of 8g1yA
1vb3A Crystal structure of threonine synthase from escherichia coli
33% identity, 88% coverage: 12:435/484 of query aligns to 11:390/428 of 1vb3A
>SMa0485 FitnessBrowser__Smeli:SMa0485
MIKYVSTTGGIEPVGFDEAVLQGFAADGGLFVPDRIPVIDQEQLQAFSTLSFQDLAFELV
SLYIDASIIPRQDLRRLIDNSYREFQRPDIVNLVPIRGNRDTYVLELFHGPTQSFKDMAM
GFLMQVVDYLLGQRRERLNIVLATTGDTGPAAAWAAAGKQRIDCWPLYPRGMISREQERQ
MTTLRADNVHPVGVENCPDGGDDLDLVVAELFSDEKLKRTLALSSVNSINWCRVMTQTVH
YFYSYYRAVERVGDPVVFSVPSGAFGNLFAGYLARSMGLPVARFVCANNVNNALHTAFSR
GVLPRHDLVQTPSSAIDIVAPYNFWRLLYFATNRDTARIRQWMKDFAARREVVLDVETTK
TIQGGFISASISDEETLATVRSVYEAEGHYLIDPHTAVAVAAVEAVRDSLPAAAAIVCFA
TAHPAKFPDVIKRALDVEELPAAGHHPVIDEARDACEHLRICQLENLRSNLIGEMTRQVA
RRRG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory