Comparing SMa2139 SMa2139 SgaA serine-glyoxylate aminotransferase (SGAT) to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
6pk1A Alanine-glyoxylate aminotransferase 1 (agt1) from arabidopsis thaliana in presence of serine (see paper)
51% identity, 97% coverage: 4:391/401 of query aligns to 6:394/399 of 6pk1A
Q56YA5 Serine--glyoxylate aminotransferase; Alanine--glyoxylate aminotransferase; AGT; Asparagine aminotransferase; Serine--pyruvate aminotransferase; EC 2.6.1.45; EC 2.6.1.44; EC 2.6.1.-; EC 2.6.1.51 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
51% identity, 97% coverage: 4:391/401 of query aligns to 8:396/401 of Q56YA5
6pk3B Alanine-glyoxylate aminotransferase 1 (agt1) from arabidopsis thaliana (see paper)
51% identity, 97% coverage: 4:391/401 of query aligns to 7:395/400 of 6pk3B
1vjoA Crystal structure of alanine--glyoxylate aminotransferase (alr1004) from nostoc sp. At 1.70 a resolution (see paper)
32% identity, 85% coverage: 8:347/401 of query aligns to 21:357/377 of 1vjoA
2huuA Crystal structure of aedes aegypti alanine glyoxylate aminotransferase in complex with alanine (see paper)
32% identity, 85% coverage: 8:348/401 of query aligns to 22:362/385 of 2huuA
2huiA Crystal structure of aedes aegypti alanine glyoxylate aminotransferase in complex with glyoxylic acid (see paper)
32% identity, 85% coverage: 8:348/401 of query aligns to 22:362/385 of 2huiA
2hufA Crystal structure of aedes aegypti alanine glyoxylate aminotransferase (see paper)
32% identity, 85% coverage: 8:348/401 of query aligns to 22:362/385 of 2hufA
Q3LSM4 Alanine--glyoxylate aminotransferase; EC 2.6.1.44 from Aedes aegypti (Yellowfever mosquito) (Culex aegypti) (see paper)
32% identity, 85% coverage: 8:348/401 of query aligns to 22:362/393 of Q3LSM4
3islA Crystal structure of ureidoglycine-glyoxylate aminotransferase (pucg) from bacillus subtilis
27% identity, 95% coverage: 8:387/401 of query aligns to 10:387/387 of 3islA
6mfbD Crystal structure of 3-hydroxykynurenine transaminase from aedes aegypti
28% identity, 84% coverage: 11:348/401 of query aligns to 24:362/386 of 6mfbD
2dr1A Crystal structure of the ph1308 protein from pyrococcus horikoshii ot3
29% identity, 88% coverage: 1:353/401 of query aligns to 12:365/381 of 2dr1A
Q0IG34 3-hydroxykynurenine transaminase; 3-hydroxykynurenine transaminase and alanine--glyoxylate aminotransferase; Ae-HKT/AGT; Alanine--glyoxylate aminotransferase; EC 2.6.1.63; EC 2.6.1.44 from Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
28% identity, 84% coverage: 11:348/401 of query aligns to 24:362/400 of Q0IG34
O32148 (S)-ureidoglycine--glyoxylate transaminase; UGXT; (S)-ureidoglycine--glyoxylate aminotransferase; Purine catabolism protein PucG; EC 2.6.1.112 from Bacillus subtilis (strain 168) (see paper)
26% identity, 95% coverage: 8:387/401 of query aligns to 14:409/416 of O32148
2yrrA Hypothetical alanine aminotransferase (tth0173) from thermus thermophilus hb8
34% identity, 85% coverage: 8:348/401 of query aligns to 3:332/352 of 2yrrA
2yriA Crystal structure of alanine-pyruvate aminotransferase with 2- methylserine
34% identity, 85% coverage: 8:348/401 of query aligns to 3:332/352 of 2yriA
2ch2A Structure of the anopheles gambiae 3-hydroxykynurenine transaminase in complex with inhibitor (see paper)
27% identity, 85% coverage: 11:352/401 of query aligns to 22:364/387 of 2ch2A
2ch1A Structure of anopheles gambiae 3-hydroxykynurenine transaminase (see paper)
27% identity, 85% coverage: 11:352/401 of query aligns to 23:365/388 of 2ch1A
3zrpA Crystal structure and substrate specificity of a thermophilic archaeal serine : pyruvate aminotransferase from sulfolobus solfataricus (see paper)
33% identity, 83% coverage: 53:383/401 of query aligns to 46:373/377 of 3zrpA
3zrqA Crystal structure and substrate specificity of a thermophilic archaeal serine : pyruvate aminotransferase from sulfolobus solfataricus (see paper)
33% identity, 83% coverage: 53:383/401 of query aligns to 50:377/382 of 3zrqA
Q7PRG3 3-hydroxykynurenine transaminase; AgHKT; Alanine--glyoxylate aminotransferase; EC 2.6.1.63; EC 2.6.1.44 from Anopheles gambiae (African malaria mosquito) (see paper)
27% identity, 85% coverage: 11:352/401 of query aligns to 24:366/396 of Q7PRG3
>SMa2139 SMa2139 SgaA serine-glyoxylate aminotransferase (SGAT)
MRNGTSHLFVPGPTNIPDAVRRAMNVPMQDMRAPDFPDLVLPLFADLKGVFRTDNGSIFL
FPGSGTGAWEAAISNTLNRGDRVLMSRFGQFSHLWADMAGRLGLDVECLDVEWGEGVPVE
EYRRRLDADKNRRIKAVFVTHNETATGVTSDVAAVRAALDDTGHKALLFVDGVSSIASIE
FRMDDWGVDLAVTGSQKGLMLPAGLGILAVSPKALEAHASSTIERCYFSFEDMKAPSETG
YFPYTPPTQLLLGLRASLDLIFAEGLDAVIARHHRLAEGVRRGVHAWGLNLCATEKKWWS
DTVSAIVVPEDVDARQVIANGYSKYRTSFGAGLSKVAGRVFRIGHLGDLNEVMCLSALAA
AEMSLRDAGAKIEAGSGVAAAQEWYRSQIGLAAPNLQERAA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory