Comparing SMc01565 FitnessBrowser__Smeli:SMc01565 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
1fc4A 2-amino-3-ketobutyrate coa ligase (see paper)
68% identity, 100% coverage: 1:395/395 of query aligns to 4:400/401 of 1fc4A
P0AB77 2-amino-3-ketobutyrate coenzyme A ligase; AKB ligase; Glycine acetyltransferase; EC 2.3.1.29 from Escherichia coli (strain K12) (see paper)
68% identity, 100% coverage: 1:395/395 of query aligns to 1:397/398 of P0AB77
3tqxA Structure of the 2-amino-3-ketobutyrate coenzyme a ligase (kbl) from coxiella burnetii (see paper)
66% identity, 99% coverage: 5:395/395 of query aligns to 4:396/396 of 3tqxA
7v58B Structural insights into the substrate selectivity of acyl-coa transferase (see paper)
65% identity, 100% coverage: 1:395/395 of query aligns to 3:399/400 of 7v58B
7bxsA 2-amino-3-ketobutyrate coa ligase from cupriavidus necator glycine binding form
58% identity, 99% coverage: 4:395/395 of query aligns to 6:399/399 of 7bxsA
7bxrA 2-amino-3-ketobutyrate coa ligase from cupriavidus necator 3- hydroxynorvaline binding form
58% identity, 99% coverage: 4:395/395 of query aligns to 6:399/399 of 7bxrA
7bxqA 2-amino-3-ketobutyrate coa ligase from cupriavidus necator l-threonine binding form
58% identity, 99% coverage: 4:395/395 of query aligns to 6:399/399 of 7bxqA
Q0P5L8 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial; AKB ligase; Aminoacetone synthase; Glycine acetyltransferase; EC 2.3.1.29 from Bos taurus (Bovine) (see paper)
56% identity, 98% coverage: 9:395/395 of query aligns to 31:418/419 of Q0P5L8
Sites not aligning to the query:
7poaA An irreversible, promiscuous and highly thermostable claisen- condensation biocatalyst drives the synthesis of substituted pyrroles
42% identity, 98% coverage: 7:395/395 of query aligns to 10:397/398 of 7poaA
3a2bA Crystal structure of serine palmitoyltransferase from sphingobacterium multivorum with substrate l-serine (see paper)
36% identity, 96% coverage: 13:391/395 of query aligns to 15:391/392 of 3a2bA
8h29A Serine palmitoyltransferase from sphingobacterium multivorum complexed with l-threonine (see paper)
36% identity, 96% coverage: 13:391/395 of query aligns to 15:391/394 of 8h29A
8h21A Serine palmitoyltransferase from sphingobacterium multivorum complexed with l-alanine (see paper)
36% identity, 96% coverage: 13:391/395 of query aligns to 15:391/394 of 8h21A
8h20A Serine palmitoyltransferase from sphingobacterium multivorum complexed with glycine (see paper)
36% identity, 96% coverage: 13:391/395 of query aligns to 15:391/394 of 8h20A
8h1yA Serine palmitoyltransferase from sphingobacterium multivorum complexed with l-homoserine (see paper)
36% identity, 96% coverage: 13:391/395 of query aligns to 15:391/394 of 8h1yA
8h1qA Serine palmitoyltransferase from sphingobacterium multivorum complexed with l-serine (see paper)
36% identity, 96% coverage: 13:391/395 of query aligns to 15:391/394 of 8h1qA
8guhA Serine palmitoyltransferase from sphingobacterium multivorum complexed with tris (see paper)
36% identity, 96% coverage: 13:391/395 of query aligns to 15:391/394 of 8guhA
Q5W264 4-hydroxy-2,2'-bipyrrole-5-methanol synthase PigH; HBM synthase; Aminotransferase PigH; EC 2.3.2.- from Serratia sp. (strain ATCC 39006) (see paper)
37% identity, 89% coverage: 45:394/395 of query aligns to 288:636/653 of Q5W264
Sites not aligning to the query:
2x8uA Sphingomonas wittichii serine palmitoyltransferase (see paper)
35% identity, 98% coverage: 9:395/395 of query aligns to 10:398/399 of 2x8uA
P08680 5-aminolevulinate synthase, erythroid-specific, mitochondrial; ALAS-E; 5-aminolevulinic acid synthase 2; Delta-ALA synthase 2; Delta-aminolevulinate synthase 2; EC 2.3.1.37 from Mus musculus (Mouse) (see 2 papers)
36% identity, 88% coverage: 47:392/395 of query aligns to 194:547/587 of P08680
Sites not aligning to the query:
5qrdB Pandda analysis group deposition -- crystal structure of human alas2a in complex with z1328968520
35% identity, 88% coverage: 47:392/395 of query aligns to 53:406/428 of 5qrdB
Sites not aligning to the query:
>SMc01565 FitnessBrowser__Smeli:SMc01565
MTTAFLSHLRSELEDLKQAGLYKSERVITSKQSGEIEVASGGRVLNFCANNYLGLADSEE
LAQAAKSALDRYGYGMASVRFICGTQEEHKELEARISSFLGMEDTILYSSCFDANGGLFE
TLLGEDDAIISDALNHASIIDGVRLSKARRFRYANNDMAALEEELKKAEGSRFKMIATDG
VFSMDGIIANLQGVCDLAEKYGAMVMVDDSHAVGFVGKHGRGSAEHCGVEGRVDIITGTL
GKALGGASGGYTSAKADVVEWLRQRSRPYLFSNTLAPVIAAASLKVFELIENGDALRNRL
YANAALFRSEMSGLGFTLAGEGHPIIPVMLGDAALAQEMAARMLKKGVYVVGFSFPVVPK
GQARIRTQMSAAHSEADVRRAIAVFEEVGRELGVI
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory