Comparing SMc02753 FitnessBrowser__Smeli:SMc02753 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 3 hits to proteins with known functional sites (download)
1vrcB Complex of enzyme iiamannose and the histidine-containing phosphocarrier protein hpr from escherichia coli nmr, restrained regularized mean structure (see paper)
30% identity, 90% coverage: 2:121/133 of query aligns to 2:123/129 of 1vrcB
P69797 PTS system mannose-specific EIIAB component; EIIAB-Man; EIII-Man; EC 2.7.1.191 from Escherichia coli (strain K12) (see 4 papers)
30% identity, 90% coverage: 2:121/133 of query aligns to 3:124/323 of P69797
Sites not aligning to the query:
P26379 PTS system fructose-specific EIIA component; EIIA-Fru; Fructose-specific phosphotransferase enzyme IIA component; lev-PTS; p16 from Bacillus subtilis (strain 168) (see paper)
26% identity, 77% coverage: 1:103/133 of query aligns to 1:104/146 of P26379
>SMc02753 FitnessBrowser__Smeli:SMc02753
MIGLVLVTHGKLADEFRHALEHVVGPQKAIETVCIGPEDDMDQRRQDILDAVEKANEGDG
VIILTDMFGGTPSNLAISVMRGGSVEVIAGVNLPMLIKLAGVRGESDMDKALVEASEAGR
KYINVASRVLSGK
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory