Comparing SMc03111 FitnessBrowser__Smeli:SMc03111 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 6 hits to proteins with known functional sites (download)
3wkiA Crystal structure of cellobiose 2-epimerase in complex with cellobiitol (see paper)
27% identity, 63% coverage: 16:260/387 of query aligns to 21:275/407 of 3wkiA
Sites not aligning to the query:
3wkhA Crystal structure of cellobiose 2-epimerase in complex with epilactose (see paper)
27% identity, 63% coverage: 16:260/387 of query aligns to 21:275/410 of 3wkhA
Sites not aligning to the query:
3wkgA Crystal structure of cellobiose 2-epimerase in complex with glucosylmannose (see paper)
27% identity, 63% coverage: 16:260/387 of query aligns to 21:275/410 of 3wkgA
Sites not aligning to the query:
8h1lB Crystal structure of glucose-2-epimerase in complex with d-glucitol from runella slithyformis runsl_4512 (see paper)
24% identity, 63% coverage: 11:252/387 of query aligns to 12:283/423 of 8h1lB
Sites not aligning to the query:
P51606 N-acylglucosamine 2-epimerase; AGE; GlcNAc 2-epimerase; N-acetyl-D-glucosamine 2-epimerase; Renin-binding protein; RnBP; EC 5.1.3.8 from Homo sapiens (Human) (see paper)
25% identity, 63% coverage: 18:261/387 of query aligns to 30:277/427 of P51606
Sites not aligning to the query:
P17560 N-acylglucosamine 2-epimerase; AGE; GlcNAc 2-epimerase; N-acetyl-D-glucosamine 2-epimerase; Renin-binding protein; RnBP; EC 5.1.3.8 from Sus scrofa (Pig) (see paper)
22% identity, 76% coverage: 18:313/387 of query aligns to 20:324/402 of P17560
>SMc03111 FitnessBrowser__Smeli:SMc03111
MGMDIHLQAGELAGWLNDAALPLWRQKGFDGEGGGFVETIDMKGEPTRDDRRSRVQPRQV
YCFAAAGRRGWDGDWRTAAEGGLLYFDRVYGQPGGFYGALANADGKLIDASFDLYNQAFA
LLAFAHLAEVLPERGAEMVGRSDKLRRQLEARCKHPLAGFEEDDPPRLPLGSNPHMHLFE
ACLASEEVEGFDRVAWANLADEIAHLAMDRFIDAESGALREFFDHDWAPFPGEKGRIVEP
GHLFEWAWLLLRWAERRGNAQAIVKARRLFEIGEKDGTCPDRDVVVMTLFDDFSVADPTA
RLWPQTEWLKAAIRFAALTEGAERERYLASAGRAAAALQRFLNVPVRGLWRDKQKADGSF
VEEPAPASTFYHILCAIYELEDCLKRM
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory