SitesBLAST
Comparing Synpcc7942_0118 FitnessBrowser__SynE:Synpcc7942_0118 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 11 hits to proteins with known functional sites (download)
3ip4B The high resolution structure of gatcab (see paper)
51% identity, 98% coverage: 11:492/494 of query aligns to 3:472/482 of 3ip4B
3al0B Crystal structure of the glutamine transamidosome from thermotoga maritima in the glutamylation state. (see paper)
49% identity, 98% coverage: 11:494/494 of query aligns to 3:481/482 of 3al0B
- binding zinc ion: C25 (≠ A33), C39 (≠ D46), C42 (≠ V49)
- binding : R225 (≠ N238), Y319 (= Y332), N349 (= N362), M352 (= M365), T353 (≠ G366), L356 (≠ A369), R357 (≠ A370), K391 (= K404), K394 (= K407), A439 (≠ E452), D442 (≠ Q455), K449 (= K462), G452 (= G465), F453 (= F466), V455 (= V468), G456 (= G469), P468 (= P481)
3h0rH Structure of tRNA-dependent amidotransferase gatcab from aquifex aeolicus (see paper)
50% identity, 85% coverage: 11:429/494 of query aligns to 3:410/410 of 3h0rH
- binding aspartic acid: H12 (= H20), K79 (= K87), E151 (= E170), Y268 (= Y287)
- binding adenosine-5'-triphosphate: V6 (= V14), E10 (= E18), V153 (= V172), T154 (≠ S173), N195 (= N214), S197 (= S216), R209 (≠ K228)
- binding manganese (ii) ion: E10 (= E18), H12 (= H20), E125 (= E137), E151 (= E170), E211 (= E230)
- binding zinc ion: C23 (≠ S31), C25 (≠ A33), C38 (≠ D46), C41 (≠ V49)
3h0rE Structure of tRNA-dependent amidotransferase gatcab from aquifex aeolicus (see paper)
50% identity, 85% coverage: 11:429/494 of query aligns to 3:410/410 of 3h0rE
- binding adenosine-5'-triphosphate: V6 (= V14), E10 (= E18), T154 (≠ S173), P156 (= P175), N195 (= N214), S197 (= S216), R209 (≠ K228)
- binding manganese (ii) ion: E10 (= E18), H12 (= H20), E125 (= E137), E151 (= E170), E211 (= E230)
- binding zinc ion: C23 (≠ S31), C25 (≠ A33), C38 (≠ D46), C41 (≠ V49)
3h0rB Structure of tRNA-dependent amidotransferase gatcab from aquifex aeolicus (see paper)
50% identity, 85% coverage: 11:429/494 of query aligns to 3:410/410 of 3h0rB
- binding adenosine-5'-diphosphate: G8 (= G16), L9 (= L17), E10 (= E18), T154 (≠ S173), P156 (= P175), N195 (= N214), S197 (= S216), R209 (≠ K228)
- binding manganese (ii) ion: E10 (= E18), H12 (= H20), E125 (= E137), E151 (= E170), N195 (= N214), E211 (= E230)
- binding zinc ion: C23 (≠ S31), C25 (≠ A33), C38 (≠ D46), C41 (≠ V49)
3h0lB Structure of tRNA-dependent amidotransferase gatcab from aquifex aeolicus (see paper)
50% identity, 85% coverage: 11:429/494 of query aligns to 3:410/410 of 3h0lB
- binding adenosine-5'-diphosphate: V6 (= V14), G8 (= G16), L9 (= L17), E10 (= E18), V153 (= V172), T154 (≠ S173), P156 (= P175), N195 (= N214), S197 (= S216), R209 (≠ K228)
- binding magnesium ion: H12 (= H20), E125 (= E137), E151 (= E170)
- binding zinc ion: C23 (≠ S31), C25 (≠ A33), C38 (≠ D46), C41 (≠ V49)
2g5iB Structure of tRNA-dependent amidotransferase gatcab complexed with adp-alf4 (see paper)
52% identity, 85% coverage: 11:431/494 of query aligns to 2:410/410 of 2g5iB
2df4B Structure of tRNA-dependent amidotransferase gatcab complexed with mn2+ (see paper)
52% identity, 83% coverage: 11:419/494 of query aligns to 2:398/399 of 2df4B
4wj3B Crystal structure of the asparagine transamidosome from pseudomonas aeruginosa (see paper)
50% identity, 83% coverage: 11:419/494 of query aligns to 1:398/456 of 4wj3B
- binding : K128 (= K142), A184 (= A205), F204 (= F225), N212 (= N233), S215 (= S236), R217 (≠ N238), V240 (≠ I261), Y311 (= Y332), N341 (= N362), M344 (= M365), V345 (≠ G366), S349 (≠ A370), N352 (= N373)
Sites not aligning to the query:
3kfuF Crystal structure of the transamidosome (see paper)
45% identity, 82% coverage: 11:415/494 of query aligns to 2:384/447 of 3kfuF
- binding magnesium ion: H11 (= H20), E120 (= E137), E146 (= E170)
- binding zinc ion: C22 (≠ S31), C24 (≠ A33), C38 (≠ D46)
- binding : Y81 (= Y89), Y83 (= Y91), D85 (= D93), Y95 (= Y103), D96 (= D104), K125 (= K142), H128 (= H145), R139 (= R163), R160 (≠ A184), P180 (≠ M204), E181 (≠ A205), G183 (= G207), R186 (= R210), N210 (= N235), S211 (= S236), F212 (= F237), K213 (≠ N238), L334 (≠ M365), G339 (≠ A370), H342 (≠ N373), S372 (≠ G403), R373 (≠ K404), K376 (= K407)
Sites not aligning to the query:
2d6fD Crystal structure of glu-tRNA(gln) amidotransferase in the complex with tRNA(gln) (see paper)
25% identity, 52% coverage: 15:269/494 of query aligns to 10:271/522 of 2d6fD