SitesBLAST

SitesBLAST – Find functional sites

SitesBLAST

Comparing Synpcc7942_0645 Synpcc7942_0645 glutamate-1-semialdehyde aminotransferase to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 20 (the maximum) hits to proteins with known functional sites (download)

2gsaA Crystal structure of glutamate-1-semialdehyde aminomutase (aminotransferase, wild-type form) (see paper)
99% identity, 94% coverage: 27:453/453 of query aligns to 1:427/427 of 2gsaA

query
sites
2gsaA

F

F

K

K

T

T

I

I

K

K

S

S

D

D

E

E

I

I

F

F

A

A

Q

Q

K

K

L

L

M

M

P

P

G

G

V
|
V

S

S

P

P

V

V

R

R

A

A

F

F

K

K

S

S

V

V

G

G

Q

Q

P

P

I

I

V

V

F

F

D

D

R

R

V

V

K

K

D

D

A

A

Y

Y

A

A

W

W

D

D

V

V

D

D

G

G

N

N

R

R

Y

Y

I

I

D

D

Y

Y

V

V

G

G

T

T

W

W

G

G

P

P

A

A

I

I

C

C

G

G

H

H

A

A

H

H

P

P

E

E

V

V

I

I

E

E

A

A

L

L

K

K

V

V

A

A

M

M

E

E

K

K

G

G

T

T

S

S

F

F

G

G

A

A

P

P

C

C

A

A

L

L

E

E

N

N

V

V

L

L

A

A

E

E

M

M

V

V

I

N

D

D

A

A

V

V

P

P

S

S

I

I

E

E

M

M

V

V

R

R

F

F

V

V

N

N

S
|
S

G
|
G

T
|
T

E

E

A

A

C

C

M

M

A

A

V

V

L

L

R

R

L

L

M

M

R

R

A

A

Y

Y

T

T

G

G

R

R

D

D

K

K

I

I

K

K

F

F

E

E

G

G

C

C

Y
|
Y

H
|
H

G
|
G

H

H

A

A

D

D

M

M

F

F

L

L

V

V

K

K

A

A

G

G

S

S

G

G

V

V

A

A

T

T

L

L

G

G

L

L

P

P

D

S

S

S

P

P

G

G

V

V

P

P

K

K

S

K

T

T

A

A

N

N

T

T

L

L

T

T

A

T

P

P

Y

Y

N

N

D

D

L

L

E

E

A

A

V

V

K

K

A

A

L

L

F

F

A

A

E

E

N

N

P

P

G

G

E

E

I

I

A

A

G

G

V

V

I

I

L

L

E
|
E

P

P

I

I

V

V

G

G

N
|
N

S

S

G

G

F

F

I

I

V

V

P

P

D

D

A

A

G

G

F

F

L

L

E

E

G

G

L

L

R

R

E

E

I

I

T

T

L

L

E

E

H

H

D

D

A

A

L

L

V

V

F

F

D
|
D

E

E

V
|
V

M
|
M

T

T

G

G

F

F

R

R

I

I

A

A

Y

Y

G

G

V

V

Q

Q

E

E

K

K

F

F

G

G

V

V

T

T

P

P

D

D

L

L

T

T

L

L

G

G

K
|
K

I

I

G

G

L

L

P

P

V

V

G

G

A

A

Y

Y

G

G

K

K

R

R

E

E

I

I

M

M

Q

Q

L

L

V

V

A

A

P

P

A

A

G

G

P

P

M

M

Y

Y

Q

Q

A

A

G
|
G

T
|
T

L

L

S

S

G

G

N

N

P

P

L

L

A

A

M

M

T

T

A

A

G

G

I

I

K

K

T

T

L

L

E

E

L

L

R

R

Q

Q

P

P

G

G

T

T

Y

Y

E

E

Y

Y

L

L

D

D

Q

Q

I

I

T

T

K

K

R

R

L

L

S

S

D

D

G

G

L

L

A

A

I

I

A

A

Q

Q

E

E

T

T

G

G

H

H

A

A

C

C

G

G

Q

Q

V

V

S

S

G

G

M

M

F

F

G

G

F

F

T

T

E

E

G

G

P

P

V

V

H

H

N

N

Y

Y

E

E

D

D

A

A

K

K

S

S

D

D

L

L

Q

Q

K

K

F

F

S

S

R

R

F

F

H

H

R

R

G

G

M

M

L

L

E

E

Q

Q

G

G

I

I

Y

Y

L

L

A

A

P

P

S

S

Q

Q

F

F

E

E

A
|
A

G

G

F

F

T

T

S

S

L

L

A

A

H

H

T

T

E

E

D

D

I

I

D

D

A

A

T

T

L

L

A

A

R

R

T

T

V

V

M

M

S

S

A

A

L

L

active site: V21 (= V47), Y144 (= Y170), E206 (= E232), D239 (= D265), M242 (= M268), K267 (= K293), A401 (= A427)
binding pyridoxal-5'-phosphate: G298 (= G324), T299 (= T325)
binding 4'-deoxy-4'-aminopyridoxal-5'-phosphate: S116 (= S142), G117 (= G143), T118 (= T144), Y144 (= Y170), H145 (= H171), G146 (= G172), E206 (= E232), N211 (= N237), D239 (= D265), V241 (= V267), M242 (= M268), K267 (= K293)

3usfA Crystal structure of dava-4
99% identity, 94% coverage: 27:453/453 of query aligns to 1:427/427 of 3usfA

query
sites
3usfA

F

F

K

K

T

T

I

I

K

K

S

S

D

D

E

E

I

I

F

F

A

A

Q

Q

K

K

L

L

M

M

P

P

G

G

V
|
V

S

S

S
|
S

P

P

V
|
V

R

R

A

A

F

F

K

K

S

S

V

V

G

G

Q

Q

P

P

I

I

V

V

F

F

D

D

R

R

V

V

K

K

D

D

A

A

Y

Y

A

A

W

W

D

D

V

V

D

D

G

G

N

N

R

R

Y

Y

I

I

D

D

Y

Y

V

V

G

G

T

T

W
|
W

G

G

P

P

A

A

I

I

C

C

G

G

H

H

A

A

H

H

P

P

E

E

V

V

I

I

E

E

A

A

L

L

K

K

V

V

A

A

M

M

E

E

K

K

G

G

T

T

S

S

F

F

G

G

A

A

P

P

C

C

A

A

L

L

E

E

N

N

V

V

L

L

A

A

E

E

M

M

V

V

I

N

D

D

A

A

V

V

P

P

S

S

I

I

E

E

M

M

V

V

R

R

F

F

V

V

N

N

S
|
S

G
|
G

T
|
T

E

E

A

A

C

C

M

M

A

A

V

V

L

L

R

R

L

I

M

M

R

R

A

A

Y

Y

T

T

G

G

R

R

D

D

K

K

I

I

K

K

F

F

E

E

G

G

C

C

Y
|
Y

H
|
H

G
|
G

H

H

A

A

D

D

M

M

F

F

L

L

V

V

K

K

A

A

G

G

S
|
S

G

G

V

V

A

A

T

T

L

L

G

G

L

L

P

P

D

S

S

S

P

P

G

G

V

V

P

P

K

K

S

K

T

T

A

A

N

N

T

T

L

L

T

T

A

T

P

P

Y

Y

N

N

D

D

L

L

E

E

A

A

V

V

K

K

A

A

L

L

F

F

A

A

E

E

N

N

P

P

G

G

E

E

I

I

A

A

G

G

V

V

I

I

L

L

E
|
E

P

P

I

I

V

V

G

G

N
|
N

S

S

G

G

F

F

I

I

V

V

P

P

D

D

A

A

G

G

F

F

L

L

E

E

G

G

L

L

R

R

E

E

I

I

T

T

L

L

E

E

H

H

D

D

A

A

L

L

V

V

F

F

D
|
D

E

E

V
|
V

M
|
M

T

T

G

G

F

F

R

R

I

I

A

A

Y

Y

G

G

V

V

Q

Q

E

E

K

K

F

F

G

G

V

V

T

T

P

P

D

D

L

L

T

T

L

L

G

G

K
|
K

I

I

G

G

L

L

P

P

V

V

G

G

A

A

Y

Y

G

G

K

K

R

R

E

E

I

I

M

M

Q

Q

L

L

V

V

A

A

P

P

A

A

G

G

P

P

M

M

Y

Y

Q

Q

A

A

G
|
G

T
|
T

L

L

S

S

G

G

N

N

P

P

L

L

A

A

M

M

T

T

A

A

G

G

I

I

K

K

T

T

L

L

E

E

L

L

R

R

Q

Q

P

P

G

G

T

T

Y

Y

E

E

Y

Y

L

L

D

D

Q

Q

I

I

T

T

K

K

R

R

L

L

S

S

D

D

G

G

L

L

A

A

I

I

A

A

Q

Q

E

E

T

T

G

G

H

H

A

A

C

C

G

G

Q

Q

V

V

S

S

G

G

M

M

F

F

G

G

F

F

T

T

E

E

G

G

P

P

V

V

H

H

N

N

Y

Y

E

E

D

D

A

A

K

K

S

S

D

D

L

L

Q

Q

K

K

F

F

S

S

R

R

F

F

H

H

R

R

G

G

M

M

L

L

E

E

Q

Q

G

G

I

I

Y

Y

L

L

A

A

P

P

S

S

Q

Q

F

F

E
|
E

A
|
A

G

G

F

F

T

T

S

S

L

L

A

A

H

H

T

T

E

E

D

D

I

I

D

D

A

A

T

T

L

L

A

A

R

R

T

T

V

V

M

M

S

S

A

A

L

L

active site: V21 (= V47), Y144 (= Y170), D239 (= D265), M242 (= M268), K267 (= K293), A401 (= A427)
binding (4s)-4,5-diaminopentanoic acid: S23 (= S49), V25 (= V51), W61 (= W87), S157 (= S183), N211 (= N237), M242 (= M268), K267 (= K293), E400 (= E426)
binding (5-hydroxy-4,6-dimethylpyridin-3-yl)methyl dihydrogen phosphate: S116 (= S142), G117 (= G143), T118 (= T144), Y144 (= Y170), H145 (= H171), G146 (= G172), E206 (= E232), N211 (= N237), D239 (= D265), V241 (= V267), M242 (= M268), K267 (= K293), G298 (= G324), T299 (= T325)

3fq7A Gabaculine complex of gsam (see paper)
99% identity, 94% coverage: 27:453/453 of query aligns to 1:427/427 of 3fq7A

query
sites
3fq7A

F

F

K

K

T

T

I

I

K

K

S

S

D

D

E

E

I

I

F

F

A

A

Q

Q

K

K

L

L

M

M

P

P

G

G

V
|
V

S

S

S
|
S

P

P

V
|
V

R

R

A

A

F

F

K

K

S

S

V

V

G

G

Q

Q

P

P

I

I

V

V

F

F

D

D

R

R

V

V

K

K

D

D

A

A

Y

Y

A

A

W

W

D

D

V

V

D

D

G

G

N

N

R

R

Y

Y

I

I

D

D

Y

Y

V

V

G

G

T

T

W
|
W

G

G

P

P

A

A

I

I

C

C

G

G

H

H

A

A

H

H

P

P

E

E

V

V

I

I

E

E

A

A

L

L

K

K

V

V

A

A

M

M

E

E

K

K

G

G

T

T

S

S

F

F

G

G

A

A

P

P

C

C

A

A

L

L

E

E

N

N

V

V

L

L

A

A

E

E

M

M

V

V

I

N

D

D

A

A

V

V

P

P

S

S

I

I

E

E

M

M

V

V

R

R

F

F

V

V

N

N

S
|
S

G
|
G

T
|
T

E

E

A

A

C
|
C

M

M

A

A

V

V

L

L

R

R

L

I

M

M

R

R

A

A

Y

Y

T

T

G

G

R

R

D

D

K

K

I

I

K

K

F

F

E

E

G

G

C

C

Y
|
Y

H
|
H

G
|
G

H

H

A

A

D

D

M

M

F

F

L

L

V

V

K

K

A

A

G

G

S
|
S

G

G

V

V

A

A

T

T

L

L

G

G

L

L

P

P

D

S

S

S

P

P

G

G

V

V

P

P

K

K

S

K

T

T

A

A

N

N

T

T

L

L

T

T

A

T

P

P

Y

Y

N

N

D

D

L

L

E

E

A

A

V

V

K

K

A

A

L

L

F

F

A

A

E

E

N

N

P

P

G

G

E

E

I

I

A

A

G

G

V

V

I

I

L

L

E
|
E

P

P

I

I

V

V

G

G

N
|
N

S

S

G

G

F

F

I

I

V

V

P

P

D

D

A

A

G

G

F

F

L

L

E

E

G

G

L

L

R

R

E

E

I

I

T

T

L

L

E

E

H

H

D

D

A

A

L

L

V

V

F

F

D
|
D

E

E

V
|
V

M
|
M

T

T

G

G

F

F

R

R

I

I

A

A

Y

Y

G

G

V

V

Q

Q

E

E

K

K

F

F

G

G

V

V

T

T

P

P

D

D

L

L

T

T

L

L

G

G

K
|
K

I

I

G

G

L

L

P

P

V

V

G

G

A

A

Y

Y

G

G

K

K

R

R

E

E

I

I

M

M

Q

Q

L

L

V

V

A

A

P

P

A

A

G

G

P

P

M

M

Y

Y

Q

Q

A
|
A

G
|
G

T
|
T

L

L

S

S

G

G

N

N

P

P

L

L

A

A

M

M

T

T

A

A

G

G

I

I

K

K

T

T

L

L

E

E

L

L

R

R

Q

Q

P

P

G

G

T

T

Y

Y

E

E

Y

Y

L

L

D

D

Q

Q

I

I

T

T

K

K

R

R

L

L

S

S

D

D

G

G

L

L

A

A

I

I

A

A

Q

Q

E

E

T

T

G

G

H

H

A

A

C

C

G

G

Q

Q

V

V

S

S

G

G

M

M

F

F

G

G

F

F

T

T

E

E

G

G

P

P

V

V

H

H

N

N

Y

Y

E

E

D

D

A

A

K

K

S

S

D

D

L

L

Q

Q

K

K

F

F

S

S

R

R

F

F

H

H

R

R

G

G

M

M

L

L

E

E

Q

Q

G

G

I

I

Y

Y

L

L

A

A

P

P

S

S

Q

Q

F

F

E
|
E

A
|
A

G

G

F

F

T

T

S

S

L

L

A

A

H

H

T

T

E

E

D

D

I

I

D

D

A

A

T

T

L

L

A

A

R

R

T

T

V

V

M

M

S

S

A

A

L

L

active site: V21 (= V47), Y144 (= Y170), D239 (= D265), M242 (= M268), K267 (= K293), A401 (= A427)
binding 3-[o-phosphonopyridoxyl]--amino-benzoic acid: S23 (= S49), V25 (= V51), W61 (= W87), S116 (= S142), G117 (= G143), T118 (= T144), C121 (= C147), Y144 (= Y170), H145 (= H171), G146 (= G172), S157 (= S183), E206 (= E232), N211 (= N237), D239 (= D265), V241 (= V267), M242 (= M268), K267 (= K293), A297 (= A323), G298 (= G324), T299 (= T325), E400 (= E426)

2hp2A Inter-subunit signaling in gsam (see paper)
99% identity, 94% coverage: 27:453/453 of query aligns to 1:427/427 of 2hp2A

query
sites
2hp2A

F

F

K

K

T

T

I

I

K

K

S

S

D

D

E

E

I

I

F

F

A

A

Q

Q

K

K

L

L

M

M

P

P

G

G

V
|
V

S

S

S
|
S

P

P

V
|
V

R

R

A

A

F

F

K

K

S

S

V

V

G

G

Q

Q

P

P

I

I

V

V

F

F

D

D

R

R

V

V

K

K

D

D

A

A

Y

Y

A

A

W

W

D

D

V

V

D

D

G

G

N

N

R

R

Y

Y

I

I

D

D

Y

Y

V

V

G

G

T

T

W
|
W

G

G

P

P

A

A

I

I

C

C

G

G

H

H

A

A

H

H

P

P

E

E

V

V

I

I

E

E

A

A

L

L

K

K

V

V

A

A

M

M

E

E

K

K

G

G

T

T

S

S

F

F

G

G

A

A

P

P

C

C

A

A

L

L

E

E

N

N

V

V

L

L

A

A

E

E

M

M

V

V

I

N

D

D

A

A

V

V

P

P

S

S

I

I

E

E

M

M

V

V

R

R

F

F

V

V

N

N

S
|
S

G
|
G

T
|
T

E

E

A

A

C
|
C

M

M

A

A

V

V

L

L

R

R

L

I

M

M

R

R

A

A

Y

Y

T

T

G

G

R

R

D

D

K

K

I

I

K

K

F

F

E

E

G

G

C

C

Y
|
Y

H
|
H

G
|
G

H

H

A

A

D

D

M

M

F

F

L

L

V

V

K

K

A

A

G

G

S

S

G

G

V

V

A

A

T

T

L

L

G

G

L

L

P

P

D

S

S

S

P

P

G

G

V

V

P

P

K

K

S

K

T

T

A

A

N

N

T

T

L

L

T

T

A

T

P

P

Y

Y

N

N

D

D

L

L

E

E

A

A

V

V

K

K

A

A

L

L

F

F

A

A

E

E

N

N

P

P

G

G

E

E

I

I

A

A

G

G

V

V

I

I

L

L

E
|
E

P

P

I

I

V

V

G

G

N
|
N

S

S

G

G

F

F

I

I

V

V

P

P

D

D

A

A

G

G

F

F

L

L

E

E

G

G

L

L

R

R

E

E

I

I

T

T

L

L

E

E

H

H

D

D

A

A

L

L

V

V

F

F

D
|
D

E

E

V
|
V

M
|
M

T

T

G

G

F

F

R

R

I

I

A

A

Y

Y

G

G

V

V

Q

Q

E

E

K

K

F

F

G

G

V

V

T

T

P

P

D

D

L

L

T

T

L

L

G

G

K
|
K

I

I

G

G

L

L

P

P

V

V

G

G

A

A

Y

Y

G

G

K

K

R

R

E

E

I

I

M

M

Q

Q

L

L

V

V

A

A

P

P

A

A

G

G

P

P

M

M

Y

Y

Q

Q

A

A

G
|
G

T
|
T

L

L

S

S

G

G

N

N

P

P

L

L

A

A

M

M

T

T

A

A

G

G

I

I

K

K

T

T

L

L

E

E

L

L

R

R

Q

Q

P

P

G

G

T

T

Y

Y

E

E

Y

Y

L

L

D

D

Q

Q

I

I

T

T

K

K

R

R

L

L

S

S

D

D

G

G

L

L

A

A

I

I

A

A

Q

Q

E

E

T

T

G

G

H

H

A

A

C

C

G

G

Q

Q

V

V

S

S

G

G

M

M

F

F

G

G

F

F

T

T

E

E

G

G

P

P

V

V

H

H

N

N

Y

Y

E

E

D

D

A

A

K

K

S

S

D

D

L

L

Q

Q

K

K

F

F

S

S

R

R

F

F

H

H

R

R

G

G

M

M

L

L

E

E

Q

Q

G

G

I

I

Y

Y

L

L

A

A

P

P

S

S

Q

Q

F

F

E
|
E

A
|
A

G

G

F

F

T

T

S

S

L

L

A

A

H

H

T

T

E

E

D

D

I

I

D

D

A

A

T

T

L

L

A

A

R

R

T

T

V

V

M

M

S

S

A

A

L

L

active site: V21 (= V47), Y144 (= Y170), D239 (= D265), M242 (= M268), K267 (= K293), A401 (= A427)
binding (4s)-4,5-diaminopentanoic acid: G298 (= G324), T299 (= T325)
binding (4r)-5-amino-4-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanoic acid: S23 (= S49), V25 (= V51), W61 (= W87), S116 (= S142), G117 (= G143), T118 (= T144), C121 (= C147), Y144 (= Y170), H145 (= H171), G146 (= G172), E206 (= E232), N211 (= N237), D239 (= D265), V241 (= V267), M242 (= M268), K267 (= K293), E400 (= E426)
binding pyridoxal-5'-phosphate: G298 (= G324), T299 (= T325)

2hp1A Inter-subunit signaling in gsam (see paper)
99% identity, 94% coverage: 27:453/453 of query aligns to 1:427/427 of 2hp1A

query
sites
2hp1A

F

F

K

K

T

T

I

I

K

K

S

S

D

D

E

E

I

I

F

F

A

A

Q

Q

K

K

L

L

M

M

P

P

G

G

V
|
V

S

S

S
|
S

P

P

V
|
V

R

R

A

A

F

F

K

K

S

S

V

V

G

G

Q

Q

P

P

I

I

V

V

F

F

D

D

R

R

V

V

K

K

D

D

A

A

Y

Y

A

A

W

W

D

D

V

V

D

D

G

G

N

N

R

R

Y

Y

I

I

D

D

Y

Y

V

V

G

G

T

T

W
|
W

G

G

P

P

A

A

I

I

C

C

G

G

H

H

A

A

H

H

P

P

E

E

V

V

I

I

E

E

A

A

L

L

K

K

V

V

A

A

M

M

E

E

K

K

G

G

T

T

S

S

F

F

G
|
G

A

A

P

P

C

C

A

A

L

L

E

E

N

N

V

V

L

L

A

A

E

E

M

M

V

V

I

N

D

D

A

A

V

V

P

P

S

S

I

I

E

E

M

M

V

V

R

R

F

F

V

V

N

N

S
|
S

G
|
G

T
|
T

E

E

A

A

C
|
C

M

M

A

A

V

V

L

L

R

R

L

I

M

M

R

R

A

A

Y

Y

T

T

G

G

R

R

D

D

K

K

I

I

K

K

F

F

E

E

G

G

C

C

Y
|
Y

H
|
H

G
|
G

H

H

A

A

D

D

M

M

F

F

L

L

V

V

K

K

A

A

G

G

S

S

G

G

V

V

A

A

T

T

L

L

G

G

L

L

P

P

D

S

S

S

P

P

G

G

V

V

P

P

K

K

S

K

T

T

A

A

N

N

T

T

L

L

T

T

A

T

P

P

Y

Y

N

N

D

D

L

L

E

E

A

A

V

V

K

K

A

A

L

L

F

F

A

A

E

E

N

N

P

P

G

G

E

E

I

I

A

A

G

G

V

V

I

I

L

L

E
|
E

P

P

I

I

V

V

G

G

N
|
N

S

S

G

G

F

F

I

I

V

V

P

P

D

D

A

A

G

G

F

F

L

L

E

E

G

G

L

L

R

R

E

E

I

I

T

T

L

L

E

E

H

H

D

D

A

A

L

L

V

V

F

F

D
|
D

E

E

V
|
V

M
|
M

T

T

G

G

F

F

R

R

I

I

A

A

Y

Y

G

G

V

V

Q

Q

E

E

K

K

F

F

G

G

V

V

T

T

P

P

D

D

L

L

T

T

L

L

G

G

K
|
K

I

I

G

G

L

L

P

P

V

V

G

G

A

A

Y

Y

G

G

K

K

R

R

E

E

I

I

M

M

Q

Q

L

L

V

V

A

A

P

P

A

A

G

G

P

P

M

M

Y

Y

Q

Q

A
|
A

G
|
G

T
|
T

L

L

S

S

G

G

N

N

P

P

L

L

A

A

M

M

T

T

A

A

G

G

I

I

K

K

T

T

L

L

E

E

L

L

R

R

Q

Q

P

P

G

G

T

T

Y

Y

E

E

Y

Y

L

L

D

D

Q

Q

I

I

T

T

K

K

R

R

L

L

S

S

D

D

G

G

L

L

A

A

I

I

A

A

Q

Q

E

E

T

T

G

G

H

H

A

A

C

C

G

G

Q

Q

V

V

S

S

G

G

M

M

F

F

G

G

F

F

T

T

E

E

G

G

P

P

V

V

H

H

N

N

Y

Y

E

E

D

D

A

A

K

K

S

S

D

D

L

L

Q

Q

K

K

F

F

S

S

R

R

F

F

H

H

R

R

G

G

M

M

L

L

E

E

Q

Q

G

G

I

I

Y

Y

L

L

A

A

P

P

S

S

Q

Q

F

F

E
|
E

A
|
A

G

G

F

F

T

T

S

S

L

L

A

A

H

H

T

T

E

E

D

D

I

I

D

D

A

A

T

T

L

L

A

A

R

R

T

T

V

V

M

M

S

S

A

A

L

L

active site: V21 (= V47), Y144 (= Y170), D239 (= D265), M242 (= M268), K267 (= K293), A401 (= A427)
binding (4s)-4-amino-5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanoic acid: S23 (= S49), V25 (= V51), W61 (= W87), S116 (= S142), G117 (= G143), T118 (= T144), C121 (= C147), Y144 (= Y170), H145 (= H171), G146 (= G172), E206 (= E232), N211 (= N237), D239 (= D265), V241 (= V267), M242 (= M268), K267 (= K293), E400 (= E426)
binding (4s)-4,5-diaminopentanoic acid: G88 (= G114), A297 (= A323), G298 (= G324), T299 (= T325)
binding pyridoxal-5'-phosphate: G298 (= G324), T299 (= T325)

2hozA Inter-subunit signaling in gsam (see paper)
99% identity, 94% coverage: 27:453/453 of query aligns to 1:427/427 of 2hozA

query
sites
2hozA

F

F

K

K

T

T

I

I

K

K

S

S

D

D

E

E

I

I

F

F

A

A

Q

Q

K

K

L

L

M

M

P

P

G

G

V
|
V

S

S

P

P

V

V

R

R

A

A

F

F

K

K

S

S

V

V

G

G

Q

Q

P

P

I

I

V

V

F

F

D

D

R

R

V

V

K

K

D

D

A

A

Y

Y

A

A

W

W

D

D

V

V

D

D

G

G

N

N

R

R

Y

Y

I

I

D

D

Y

Y

V

V

G

G

T

T

W

W

G

G

P

P

A

A

I

I

C

C

G

G

H

H

A

A

H

H

P

P

E

E

V

V

I

I

E

E

A

A

L

L

K

K

V

V

A

A

M

M

E

E

K

K

G

G

T

T

S

S

F

F

G

G

A

A

P

P

C

C

A

A

L

L

E

E

N

N

V

V

L

L

A

A

E

E

M

M

V

V

I

N

D

D

A

A

V

V

P

P

S

S

I

I

E

E

M

M

V

V

R

R

F

F

V

V

N

N

S
|
S

G
|
G

T
|
T

E

E

A

A

C
|
C

M

M

A

A

V

V

L

L

R

R

L

I

M

M

R

R

A

A

Y

Y

T

T

G

G

R

R

D

D

K

K

I

I

K

K

F

F

E
|
E

G

G

C

C

Y
|
Y

H
|
H

G
|
G

H

H

A

A

D

D

M

M

F

F

L

L

V

V

K

K

A

A

G
|
G

S
|
S

G

G

V

V

A

A

T

T

L

L

G

G

L

L

P

P

D

S

S

S

P

P

G

G

V

V

P

P

K

K

S

K

T

T

A

A

N

N

T

T

L

L

T

T

A

T

P
|
P

Y

Y

N

N

D

D

L

L

E

E

A

A

V

V

K

K

A

A

L

L

F

F

A

A

E

E

N

N

P

P

G

G

E

E

I

I

A

A

G

G

V

V

I

I

L

L

E
|
E

P

P

I

I

V

V

G

G

N
|
N

S

S

G

G

F

F

I

I

V

V

P

P

D

D

A

A

G

G

F

F

L

L

E

E

G

G

L

L

R

R

E

E

I

I

T

T

L

L

E

E

H

H

D

D

A

A

L

L

V

V

F

F

D
|
D

E

E

V
|
V

M
|
M

T

T

G

G

F

F

R

R

I

I

A

A

Y

Y

G

G

V

V

Q

Q

E

E

K

K

F

F

G

G

V

V

T

T

P

P

D

D

L

L

T

T

L

L

G

G

K
|
K

I

I

G

G

L

L

P

P

V

V

G

G

A

A

Y

Y

G

G

K

K

R

R

E

E

I

I

M

M

Q

Q

L

L

V

V

A

A

P

P

A

A

G

G

P

P

M

M

Y

Y

Q

Q

A

A

G
|
G

T
|
T

L

L

S

S

G

G

N

N

P

P

L

L

A

A

M

M

T

T

A

A

G

G

I

I

K

K

T

T

L

L

E

E

L

L

R

R

Q

Q

P

P

G

G

T

T

Y

Y

E

E

Y

Y

L

L

D

D

Q

Q

I

I

T

T

K

K

R

R

L

L

S

S

D

D

G

G

L

L

A

A

I

I

A

A

Q

Q

E

E

T

T

G

G

H

H

A

A

C

C

G

G

Q

Q

V

V

S

S

G

G

M

M

F

F

G

G

F

F

T

T

E

E

G

G

P

P

V

V

H

H

N
|
N

Y

Y

E
|
E

D

D

A

A

K
|
K

K

K

S

S

D

D

L

L

Q

Q

K

K

F

F

S

S

R

R

F

F

H

H

R

R

G

G

M

M

L

L

E

E

Q

Q

G

G

I

I

Y

Y

L

L

A

A

P

P

S

S

Q

Q

F

F

E

E

A
|
A

G

G

F

F

T

T

S

S

L

L

A

A

H

H

T

T

E

E

D

D

I

I

D

D

A

A

T

T

L

L

A

A

R

R

T

T

V

V

M

M

S

S

A

A

L

L

active site: V21 (= V47), Y144 (= Y170), D239 (= D265), M242 (= M268), K267 (= K293), A401 (= A427)
binding (4s)-4,5-diaminopentanoic acid: E141 (= E167), G156 (= G182), S157 (= S183), P182 (= P208), N368 (= N394), E370 (= E396), K373 (= K399)
binding 4'-deoxy-4'-aminopyridoxal-5'-phosphate: S116 (= S142), G117 (= G143), T118 (= T144), C121 (= C147), Y144 (= Y170), H145 (= H171), G146 (= G172), E206 (= E232), N211 (= N237), D239 (= D265), V241 (= V267), M242 (= M268), K267 (= K293), G298 (= G324), T299 (= T325)

3fqaA Gabaculien complex of gabaculine resistant gsam version (see paper)
99% identity, 94% coverage: 28:453/453 of query aligns to 1:426/426 of 3fqaA

query
sites
3fqaA

K

K

T

T

I

I

K

K

S

S

D

D

E

E

I

I

F

F

A

A

Q

Q

K

K

L

L

M

M

P

P

G

G

V
|
V

S

S

S
|
S

P

P

V

V

R
|
R

A

A

F

F

K

K

S

S

V

V

G

G

Q

Q

P

P

I

I

V

V

F

F

D

D

R

R

V

V

K

K

D

D

A

A

Y

Y

A

A

W

W

D

D

V

V

D

D

G

G

N

N

R

R

Y

Y

I

I

D

D

Y

Y

V

V

G

G

T

T

W
|
W

G

G

P

P

A

A

I

I

C

C

G

G

H

H

A

A

H

H

P

P

E

E

V

V

I

I

E

E

A

A

L

L

K

K

V

V

A

A

M

M

E

E

K

K

G

G

T

T

S

S

F

F

G

G

A

A

P

P

C

C

A

A

L

L

E

E

N

N

V

V

L

L

A

A

E

E

M

M

V

V

I

N

D

D

A

A

V

V

P

P

S

S

I

I

E

E

M

M

V

V

R

R

F

F

V

V

N

N

S
|
S

G
|
G

T
|
T

E

E

A

A

C
|
C

M

M

A

A

V

V

L

L

R

R

L

L

M

M

R

R

A

A

Y

Y

T

T

G

G

R

R

D

D

K

K

I

I

K

K

F

F

E

E

G

G

C

C

Y
|
Y

H
|
H

G
|
G

H

H

A

A

D

D

M

M

F

F

L

L

V

V

K

K

A

A

G

G

S
|
S

G

G

V

V

A

A

T

T

L

L

G

G

L

L

P

P

D

S

S

S

P

P

G

G

V

V

P

P

K

K

S

K

T

T

A

A

N

N

T

T

L

L

T

T

A

T

P

P

Y

Y

N

N

D

D

L

L

E

E

A

A

V

V

K

K

A

A

L

L

F

F

A

A

E

E

N

N

P

P

G

G

E

E

I

I

A

A

G

G

V

V

I

I

L

L

E
|
E

P

P

I

I

V

V

G

G

N
|
N

S

S

G

G

F

F

I

I

V

V

P

P

D

D

A

A

G

G

F

F

L

L

E

E

G

G

L

L

R

R

E

E

I

I

T

T

L

L

E

E

H

H

D

D

A

A

L

L

V

V

F

F

D
|
D

E

E

V
|
V

M
x
I

T

T

G

G

F

F

R

R

I

I

A

A

Y

Y

G

G

V

V

Q

Q

E

E

K

K

F

F

G

G

V

V

T

T

P

P

D

D

L

L

T

T

L

L

G

G

K
|
K

I

I

G

G

L

L

P

P

V

V

G

G

A

A

Y

Y

G

G

K

K

R

R

E

E

I

I

M

M

Q

Q

L

L

V

V

A

A

P

P

A

A

G

G

P

P

M

M

Y

Y

Q

Q

A

A

G
|
G

T
|
T

L

L

S

S

G

G

N

N

P

P

L

L

A

A

M

M

T

T

A

A

G

G

I

I

K

K

T

T

L

L

E

E

L

L

R

R

Q

Q

P

P

G

G

T

T

Y

Y

E

E

Y

Y

L

L

D

D

Q

Q

I

I

T

T

K

K

R

R

L

L

S

S

D

D

G

G

L

L

A

A

I

I

A

A

Q

Q

E

E

T

T

G

G

H

H

A

A

C

C

G

G

Q

Q

V

V

S

S

G

G

M

M

F

F

G

G

F

F

T

T

E

E

G

G

P

P

V

V

H

H

N

N

Y

Y

E

E

D

D

A

A

K

K

S

S

D

D

L

L

Q

Q

K

K

F

F

S

S

R

R

F

F

H

H

R

R

G

G

M

M

L

L

E

E

Q

Q

G

G

I

I

Y

Y

L

L

A

A

P

P

S

S

Q

Q

F

F

E

E

A
|
A

G

G

F

F

T

T

S

S

L

L

A

A

H

H

T

T

E

E

D

D

I

I

D

D

A

A

T

T

L

L

A

A

R

R

T

T

V

V

M

M

S

S

A

A

L

L

active site: V20 (= V47), Y143 (= Y170), D238 (= D265), I241 (≠ M268), K266 (= K293), A400 (= A427)
binding 3-aminobenzoic acid: S22 (= S49), R25 (= R52), W60 (= W87), Y143 (= Y170), S156 (= S183)
binding 4'-deoxy-4'-aminopyridoxal-5'-phosphate: S115 (= S142), G116 (= G143), T117 (= T144), C120 (= C147), Y143 (= Y170), H144 (= H171), G145 (= G172), E205 (= E232), N210 (= N237), D238 (= D265), V240 (= V267), I241 (≠ M268), K266 (= K293), G297 (= G324), T298 (= T325)

3usfB Crystal structure of dava-4
93% identity, 94% coverage: 27:453/453 of query aligns to 1:402/402 of 3usfB

query
sites
3usfB

F

F

K

K

T

T

I

I

K

K

S

S

D

D

E

E

I

I

F

F

A

A

Q

Q

K

K

L

L

M

M

P

P

G

G

V
|
V

S

S

P

P

V

V

R

R

A

A

F

F

K

K

S

S

V

V

G

G

Q

Q

P

P

I

I

V

V

F

F

D

D

R

R

V

V

K

K

D

D

A

A

Y

Y

A

A

W

W

D

D

V

V

D

D

G

G

N

N

R

R

Y

Y

I

I

D

D

Y

Y

V

V

G

G

T

T

W

W

G

G

P

P

A

A

I

I

C

C

G

G

H

H

A

A

H

H

P

P

E

E

V

V

I

I

E

E

A

A

L

L

K

K

V

V

A

A

M

M

E

E

K

K

G

G

T

T

S

S

F

F

G

G

A

A

P

P

C

C

A

A

L

L

E

E

N

N

V

V

L

L

A

A

E

E

M

M

V

V

I

N

D

D

A

A

V

V

P

P

S

S

I

I

E

E

M

M

V

V

R

R

F

F

V

V

N

N

S
|
S

G
|
G

T
|
T

E

E

A

A

C

C

M

M

A

A

V

V

L

L

R

R

L

I

M

M

R

R

A

A

Y

Y

T

T

G

G

R

R

D

D

K

K

I

I

K

K

F

F

E

E

G

G

C

C

Y
|
Y

H
|
H

G

G

H

H

A

A

D

D

M

-

F

-

L

-

V

-

K

-

A

-

G

-

S

-

G

-

V

-

A

-

T

-

L

-

G

-

L

-

P

-

D

-

S

-

P

-

G

-

V

-

P

-

K

-

S

-

T

-

T

T

A

A

N

N

T

T

L

L

T

T

A

T

P

P

Y

Y

N

N

D

D

L

L

E

E

A

A

V

V

K

K

A

A

L

L

F

F

A

A

E

E

N

N

P

P

G

G

E

E

I

I

A

A

G

G

V

V

I

I

L

L

E
|
E

P

P

I

I

V

V

G

G

N
|
N

S

S

G

G

F

F

I

I

V

V

P

P

D

D

A

A

G

G

F

F

L

L

E

E

G

G

L

L

R

R

E

E

I

I

T

T

L

L

E

E

H

H

D

D

A

A

L

L

V

V

F

F

D
|
D

E

E

V
|
V

M
|
M

T

T

G

G

F

F

R

R

I

I

A

A

Y

Y

G

G

V

V

Q

Q

E

E

K

K

F

F

G

G

V

V

T

T

P

P

D

D

L

L

T

T

L

L

G

G

K
|
K

I

I

G

G

L

L

P

P

V

V

G

G

A

A

Y

Y

G

G

K

K

R

R

E

E

I

I

M

M

Q

Q

L

L

V

V

A

A

P

P

A

A

G

G

P

P

M

M

Y

Y

Q

Q

A
|
A

G
|
G

T
|
T

L

L

S

S

G

G

N

N

P

P

L

L

A

A

M

M

T

T

A

A

G

G

I

I

K

K

T

T

L

L

E

E

L

L

R

R

Q

Q

P

P

G

G

T

T

Y

Y

E

E

Y

Y

L

L

D

D

Q

Q

I

I

T

T

K

K

R

R

L

L

S

S

D

D

G

G

L

L

A

A

I

I

A

A

Q

Q

E

E

T

T

G

G

H

H

A

A

C

C

G

G

Q

Q

V

V

S

S

G

G

M

M

F

F

G

G

F

F

T

T

E

E

G

G

P

P

V

V

H

H

N

N

Y

Y

E

E

D

D

A

A

K

K

S

S

D

D

L

L

Q

Q

K

K

F

F

S

S

R

R

F

F

H

H

R

R

G

G

M

M

L

L

E

E

Q

Q

G

G

I

I

Y

Y

L

L

A

A

P

P

S

S

Q

Q

F

F

E

E

A
|
A

G

G

F

F

T

T

S

S

L

L

A

A

H

H

T

T

E

E

D

D

I

I

D

D

A

A

T

T

L

L

A

A

R

R

T

T

V

V

M

M

S

S

A

A

L

L

active site: V21 (= V47), Y144 (= Y170), E181 (= E232), D214 (= D265), M217 (= M268), K242 (= K293), A376 (= A427)
binding (4s)-4,5-diaminopentanoic acid: A272 (= A323), G273 (= G324), T274 (= T325)
binding (5-hydroxy-4,6-dimethylpyridin-3-yl)methyl dihydrogen phosphate: S116 (= S142), G117 (= G143), T118 (= T144), Y144 (= Y170), H145 (= H171), E181 (= E232), N186 (= N237), D214 (= D265), V216 (= V267), M217 (= M268), K242 (= K293), G273 (= G324), T274 (= T325)

2hp1B Inter-subunit signaling in gsam (see paper)
93% identity, 94% coverage: 27:453/453 of query aligns to 1:398/398 of 2hp1B

query
sites
2hp1B

F

F

K

K

T

T

I

I

K

K

S

S

D

D

E

E

I

I

F

F

A

A

Q

Q

K

K

L

L

M

M

P

P

G

G

V
|
V

S

S

S
|
S

P

P

V
|
V

R
|
R

A

A

F

F

K

K

S

S

V

V

G

G

Q

Q

P

P

I

I

V

V

F

F

D

D

R

R

V

V

K

K

D

D

A

A

Y

Y

A

A

W

W

D

D

V

V

D

D

G

G

N

N

R

R

Y

Y

I

I

D

D

Y

Y

V

V

G

G

T

T

W
|
W

G

G

P

P

A

A

I

I

C

C

G

G

H

H

A

A

H

H

P

P

E

E

V

V

I

I

E

E

A

A

L

L

K

K

V

V

A

A

M

M

E

E

K

K

G

G

T

T

S

S

F

F

G

G

A

A

P

P

C

C

A

A

L

L

E

E

N

N

V

V

L

L

A

A

E

E

M

M

V

V

I

N

D

D

A

A

V

V

P

P

S

S

I

I

E

E

M

M

V

V

R

R

F

F

V

V

N

N

S
|
S

G
|
G

T
|
T

E

E

A

A

C

C

M

M

A

A

V

V

L

L

R

R

L

I

M

M

R

R

A

A

Y

Y

T

T

G

G

R

R

D

D

K

K

I

I

K

K

F

F

E

E

G

G

C

C

Y
|
Y

H
|
H

G

G

H

H

A

-

D

-

M

-

F

-

L

-

V

-

K

-

A

-

G

-

S

-

G

-

V

-

A

-

T

-

L

-

G

-

L

-

P

-

D

-

S

-

P

-

G

-

V

-

P

-

K

-

S

-

T

-

A

-

N

N

T

T

L

L

T

T

A

T

P

P

Y

Y

N

N

D

D

L

L

E

E

A

A

V

V

K

K

A

A

L

L

F

F

A

A

E

E

N

N

P

P

G

G

E

E

I

I

A

A

G

G

V

V

I

I

L

L

E
|
E

P

P

I

I

V

V

G

G

N
|
N

S

S

G

G

F

F

I

I

V

V

P

P

D

D

A

A

G

G

F

F

L

L

E

E

G

G

L

L

R

R

E

E

I

I

T

T

L

L

E

E

H

H

D

D

A

A

L

L

V

V

F

F

D
|
D

E

E

V
|
V

M
|
M

T

T

G

G

F

F

R

R

I

I

A

A

Y

Y

G

G

V

V

Q

Q

E

E

K

K

F

F

G

G

V

V

T

T

P

P

D

D

L

L

T

T

L

L

G

G

K
|
K

I

I

G

G

L

L

P

P

V

V

G

G

A

A

Y

Y

G

G

K

K

R

R

E

E

I

I

M

M

Q

Q

L

L

V

V

A

A

P

P

A

A

G

G

P

P

M

M

Y

Y

Q

Q

A

A

G
|
G

T
|
T

L

L

S

S

G

G

N

N

P

P

L

L

A

A

M

M

T

T

A

A

G

G

I

I

K

K

T

T

L

L

E

E

L

L

R

R

Q

Q

P

P

G

G

T

T

Y

Y

E

E

Y

Y

L

L

D

D

Q

Q

I

I

T

T

K

K

R

R

L

L

S

S

D

D

G

G

L

L

A

A

I

I

A

A

Q

Q

E

E

T

T

G

G

H

H

A

A

C

C

G

G

Q

Q

V

V

S

S

G

G

M

M

F

F

G

G

F

F

T

T

E

E

G

G

P

P

V

V

H

H

N

N

Y

Y

E

E

D

D

A

A

K

K

S

S

D

D

L

L

Q

Q

K

K

F

F

S

S

R

R

F

F

H

H

R

R

G

G

M

M

L

L

E

E

Q

Q

G

G

I

I

Y

Y

L

L

A

A

P

P

S

S

Q

Q

F

F

E

E

A
|
A

G

G

F

F

T

T

S

S

L

L

A

A

H

H

T

T

E

E

D

D

I

I

D

D

A

A

T

T

L

L

A

A

R

R

T

T

V

V

M

M

S

S

A

A

L

L

active site: V21 (= V47), Y144 (= Y170), E177 (= E232), D210 (= D265), M213 (= M268), K238 (= K293), A372 (= A427)
binding (4s)-4-amino-5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanoic acid: G269 (= G324), T270 (= T325)
binding (4s)-4,5-diaminopentanoic acid: S23 (= S49), V25 (= V51), R26 (= R52), W61 (= W87), Y144 (= Y170)
binding pyridoxal-5'-phosphate: S116 (= S142), G117 (= G143), T118 (= T144), Y144 (= Y170), H145 (= H171), E177 (= E232), N182 (= N237), D210 (= D265), V212 (= V267), M213 (= M268), K238 (= K293)

Q42522 Glutamate-1-semialdehyde 2,1-aminomutase 2, chloroplastic; GSA 2; Glutamate-1-semialdehyde aminotransferase 2; GSA-AT 2; EC 5.4.3.8 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
74% identity, 95% coverage: 24:453/453 of query aligns to 43:472/472 of Q42522

query
sites
Q42522

S

T

S

K

P

K

F

F

K

T

T

L

I

Q

K

K

S

S

D

E

E

E

I

A

F

F

A

N

A

A

Q

K

K

N

L

L

M

M

P

P

G

G

V

V

S

N

S

S

P

P

V

V

R

R

A

A

F

F

K

K

S

S

V

V

G

G

Q

Q

P

P

I

V

V

V

F

M

D

D

R

S

V

A

K

K

D

G

A

S

Y

R

A

I

W
x
R

D

D

V

I

D

D

G

G

N

N

R

E

Y

Y

I

I

D

D

Y

Y

V

V

G

G

T

S

W

W

G

G

P

P

A

A

I

I

C

I

G

G

H

H

A

A

H

D

P

D

E

E

V

V

I

L

E

A

A

A

L

L

K

A

V

E

A

T

M

M

E

K

K

K

G

G

T

T

S

S

F

F

G

G

A

A

P

P

C

C

A

L

L

L

E

E

N

N

V

V

L

L

A

A

E

E

M

M

V

V

I

I

D

S

A

A

V

V

P

P

S

S

I

I

E

E

M

M

V

V

R

R

F

F

V

V

N

N

S

S

G
|
G

T

T

E

E

A

A

C

C

M

M

A

G

V

V

L

L

R

R

L

L

M

A

R

R

A

A

Y

F

T

T

G

G

R

K

D

Q

K

K

I

F

I

I

K

K

F

F

E

E

G

G

C

C

Y

Y

H

H

G

G

H

H

A

A

D

N

M

S

F

F

L

L

V

V

K

K

A

A

G

G

S

S

G

G

V

V

A

A

T

T

L

L

G

G

L

L

P

P

D

D

S

S

P

P

G

G

V

V

P

P

K

K

S

A

T

A

T

T

A

S

N

D

T

T

L

L

T

T

A

A

P

P

Y

Y

N

N

D

D

L

I

E

A

A

A

V

V

K

E

A

K

L

L

F

F

A

E

E

A

N

N

P

K

G

G

E

E

I

I

A

A

G

A

V

I

I

I

L

L

E

E

P

P

I

V

V

V

G

G

N

N

S

S

G

G

F

F

I

I

V

T

P

P

D

K

A

P

G

E

F

F

L

I

E

E

G

G

L

I

R

R

E

R

I

I

T

T

L

K

E

D

H

N

D

G

A

A

L

L

V

I

F

F

D

D

E

E

V

V

M

M

T

T

G

G

F

F

R

R

I

L

A

A

Y

Y

G

G

V

A

Q

Q

E

E

K

Y

F

F

G

G

V

I

T

T

P

P

D

D

L

L

T

T

L

L

G

G

K

K

I

I

G

G

L

L

P

P

V

V

G

G

A

A

Y

Y

G

G

K

R

R

R

E

D

I

I

M

M

Q

E

L

M

V

V

A

A

P

P

A

A

G

G

P

P

M

M

Y

Y

Q

Q

A

A

G

G

T

T

L

L

S

S

G

G

N

N

P

P

L

L

A

A

M

M

T

T

A

A

G

G

I

I

K

H

T

T

L

L

E

K

L

R

L

L

R

S

Q

Q

P

P

G

G

T

T

Y

Y

E

E

Y

Y

L

L

D

D

Q

K

I

I

T

T

K

K

R

E

L

L

S

T

D

N

G

G

L

I

L

L

A

E

I

A

A

G

Q

K

E

K

T

T

G

G

H

H

A

A

A

M

C

C

G

G

Q

Y

V

I

S

S

G

G

M

M

F

F

G

G

F

F

T

T

E

E

G

G

P

P

V

V

H

Y

N

D

Y

F

E

S

D

D

A

A

K

K

S

S

D

D

L

T

Q

E

K

K

F

F

S

G

R

K

F

F

H

F

R

R

G

G

M

M

L

L

E

E

Q

E

G

G

I

V

Y

Y

L

L

A

A

P

P

S

S

Q

Q

F

F

E

E

A

A

G

G

F

F

T

T

S

S

L

L

A

A

H

H

T

T

E

S

E

E

D

D

I

I

D

Q

A

F

T

T

L

I

A

A

R

E

T

K

V

V

M

L

S

S

A

R

L

L

R92 (≠ W73) mutation to K: In gsa2-1; suppression of enf1 mutant pleiotropic developmental phenotypes; when associated with S-162.
G162 (= G143) mutation to S: In gsa2-1; suppression of enf1 mutant pleiotropic developmental phenotypes; when associated with K-92.

P42799 Glutamate-1-semialdehyde 2,1-aminomutase 1, chloroplastic; AtGSA1; GSA 1; Glutamate-1-semialdehyde aminotransferase 1; GSA-AT 1; EC 5.4.3.8 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
70% identity, 100% coverage: 2:453/453 of query aligns to 22:474/474 of P42799

query
sites
P42799

R

K

R

R

L

V

S

S

A

S

S

S

L

P

A

A