Comparing Synpcc7942_0853 Synpcc7942_0853 L,L-diaminopimelate aminotransferase to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
3qguA L,l-diaminopimelate aminotransferase from chlamydomonas reinhardtii (see paper)
50% identity, 98% coverage: 5:408/411 of query aligns to 8:404/406 of 3qguA
Sites not aligning to the query:
Q9ZQI7 Aminotransferase ALD1, chloroplastic; AGD2-like defense response protein 1; EC 2.6.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
42% identity, 98% coverage: 5:407/411 of query aligns to 41:437/456 of Q9ZQI7
4fl0B Crystal structure of ald1 from arabidopsis thaliana (see paper)
42% identity, 98% coverage: 5:407/411 of query aligns to 8:404/409 of 4fl0B
Q93ZN9 LL-diaminopimelate aminotransferase, chloroplastic; AtDAP-AT; DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase; Protein ABERRANT GROWTH AND DEATH 2; EC 2.6.1.83 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
46% identity, 98% coverage: 5:406/411 of query aligns to 62:457/461 of Q93ZN9
3ei6A Crystal structure of ll-diaminopimelate aminotransferase from arabidopsis thaliana complexed with plp-dap: an external aldimine mimic (see paper)
46% identity, 98% coverage: 5:406/411 of query aligns to 9:404/410 of 3ei6A
3ei5A Crystal structure of ll-diaminopimelate aminotransferase from arabidopsis thaliana complexed with plp-glu: an external aldimine mimic (see paper)
46% identity, 98% coverage: 5:406/411 of query aligns to 9:404/408 of 3ei5A
2z1zA Crystal structure of ll-diaminopimelate aminotransferase from arabidopsis thaliana complexed with l-malate ion (see paper)
46% identity, 98% coverage: 5:406/411 of query aligns to 9:404/408 of 2z1zA
3ei8A Crystal structure of k270n variant of ll-diaminopimelate aminotransferase from arabidopsis thaliana complexed with ll-dap: external aldimine form (see paper)
46% identity, 98% coverage: 5:406/411 of query aligns to 9:404/411 of 3ei8A
3ei9A Crystal structure of k270n variant of ll-diaminopimelate aminotransferase from arabidopsis thaliana complexed with l-glu: external aldimine form (see paper)
46% identity, 98% coverage: 5:406/411 of query aligns to 9:404/412 of 3ei9A
O84395 LL-diaminopimelate aminotransferase; DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase; EC 2.6.1.83 from Chlamydia trachomatis (strain D/UW-3/Cx) (see paper)
41% identity, 98% coverage: 5:408/411 of query aligns to 4:389/394 of O84395
6l1oB Product bound bacf structure from bacillus subtillis (see paper)
30% identity, 92% coverage: 34:410/411 of query aligns to 32:389/392 of 6l1oB
Sites not aligning to the query:
6l1lB Apo-bacf structure from bacillus subtillis (see paper)
30% identity, 92% coverage: 34:410/411 of query aligns to 32:389/393 of 6l1lB
6l1nA Substrate bound bacf structure from bacillus subtillis (see paper)
30% identity, 92% coverage: 34:410/411 of query aligns to 31:388/393 of 6l1nA
Sites not aligning to the query:
2x5dD Crystal structure of a probable aminotransferase from pseudomonas aeruginosa (see paper)
27% identity, 91% coverage: 36:407/411 of query aligns to 19:373/380 of 2x5dD
1gdeA Crystal structure of pyrococcus protein a-1 e-form (see paper)
26% identity, 90% coverage: 36:405/411 of query aligns to 27:378/388 of 1gdeA
1gd9A Crystall structure of pyrococcus protein-a1 (see paper)
26% identity, 90% coverage: 36:405/411 of query aligns to 27:378/388 of 1gd9A
P14909 Aspartate aminotransferase; AspAT; Transaminase A; EC 2.6.1.1 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
24% identity, 95% coverage: 16:406/411 of query aligns to 21:392/402 of P14909
Sites not aligning to the query:
Q58097 (5-formylfuran-3-yl)methyl phosphate transaminase; 4-HFC-P:alanine aminotransferase; EC 2.6.1.108 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
24% identity, 90% coverage: 36:406/411 of query aligns to 31:365/370 of Q58097
2o1bA Structure of aminotransferase from staphylococcus aureus
30% identity, 53% coverage: 175:390/411 of query aligns to 152:353/376 of 2o1bA
Sites not aligning to the query:
5wmiA Arabidopsis thaliana prephenate aminotransferase mutant- t84v (see paper)
24% identity, 91% coverage: 36:408/411 of query aligns to 31:395/402 of 5wmiA
Sites not aligning to the query:
>Synpcc7942_0853 Synpcc7942_0853 L,L-diaminopimelate aminotransferase
MATINDNYLKLKAGYLFPEIARRVNAFAQSNPEAAIIRLGIGDVTEPLPVACRQAMIQAV
EDMGQRENFKGYGPEQGYAWLREKIAAHDFQSRGCEVDASEIFISDGSKCDCGNILDIFG
NNNRIAVTDPVYPVYVDTNVMAGHTGDANDRGEYDGLVYLPISAENNFTAEIPSEKVDLI
YLCFPNNPTGAVASREYLQAWVDYARANGAIILFDAAYEAFITDPAIPHSIFEIPGARDC
AIEFRSFSKNAGFTGTRCAFTVVPKGLKGKAADGSEVELWGLWNRRQSTKFNGVSYIVQR
GAEAVYSAEGQAQIKELVAFYLENARIIREELTAAGLDVHGGVNAPYVWVKTPAGLTSWD
FFDKLLQVCNVVGTPGSGFGAAGEGYFRISAFNSRENVVTAMQRIRSAGLA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory