Comparing Synpcc7942_0937 FitnessBrowser__SynE:Synpcc7942_0937 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4ysbA Crystal structure of ethe1 from myxococcus xanthus (see paper)
55% identity, 98% coverage: 1:226/230 of query aligns to 1:225/225 of 4ysbA
5ve5A Crystal structure of persulfide dioxygenase rhodanese fusion protein with rhodanese domain inactivating mutation (c314s) from burkholderia phytofirmans in complex with glutathione (see paper)
46% identity, 98% coverage: 1:225/230 of query aligns to 4:231/350 of 5ve5A
Q9C8L4 Persulfide dioxygenase ETHE1 homolog, mitochondrial; Glyoxalase II; Glx II; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
44% identity, 98% coverage: 1:225/230 of query aligns to 52:285/294 of Q9C8L4
2gcuA X-ray structure of gene product from arabidopsis thaliana at1g53580 (see paper)
44% identity, 98% coverage: 1:225/230 of query aligns to 3:236/244 of 2gcuA
4chlB Human ethylmalonic encephalopathy protein 1 (hethe1) (see paper)
45% identity, 98% coverage: 1:225/230 of query aligns to 7:232/237 of 4chlB
O95571 Persulfide dioxygenase ETHE1, mitochondrial; Ethylmalonic encephalopathy protein 1; Hepatoma subtracted clone one protein; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Homo sapiens (Human) (see 4 papers)
45% identity, 98% coverage: 1:225/230 of query aligns to 23:248/254 of O95571
Sites not aligning to the query:
4efzA Crystal structure of a hypothetical metallo-beta-lactamase from burkholderia pseudomallei
30% identity, 98% coverage: 1:225/230 of query aligns to 5:275/295 of 4efzA
3r2uB 2.1 angstrom resolution crystal structure of metallo-beta-lactamase from staphylococcus aureus subsp. Aureus col
29% identity, 92% coverage: 1:211/230 of query aligns to 5:232/336 of 3r2uB
Sites not aligning to the query:
4yslA Crystal structure of sdoa from pseudomonas putida in complex with glutathione (see paper)
29% identity, 96% coverage: 6:226/230 of query aligns to 12:275/294 of 4yslA
4yskA Crystal structure of apo-form sdoa from pseudomonas putida (see paper)
29% identity, 96% coverage: 6:226/230 of query aligns to 12:275/294 of 4yskA
3r2uA 2.1 angstrom resolution crystal structure of metallo-beta-lactamase from staphylococcus aureus subsp. Aureus col
27% identity, 92% coverage: 1:211/230 of query aligns to 3:244/348 of 3r2uA
3tp9A Crystal structure of alicyclobacillus acidocaldarius protein with beta-lactamase and rhodanese domains
26% identity, 87% coverage: 1:200/230 of query aligns to 3:235/473 of 3tp9A
O24496 Hydroxyacylglutathione hydrolase cytoplasmic; Glyoxalase II; Glx II; EC 3.1.2.6 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
35% identity, 70% coverage: 13:173/230 of query aligns to 12:176/258 of O24496
Sites not aligning to the query:
2xf4A Crystal structure of salmonella enterica serovar typhimurium ycbl (see paper)
32% identity, 77% coverage: 17:192/230 of query aligns to 17:208/210 of 2xf4A
1qh5B Human glyoxalase ii with s-(n-hydroxy-n-bromophenylcarbamoyl) glutathione (see paper)
32% identity, 70% coverage: 14:173/230 of query aligns to 13:175/260 of 1qh5B
Sites not aligning to the query:
1qh5A Human glyoxalase ii with s-(n-hydroxy-n-bromophenylcarbamoyl) glutathione (see paper)
32% identity, 70% coverage: 14:173/230 of query aligns to 13:175/260 of 1qh5A
Sites not aligning to the query:
1qh3A Human glyoxalase ii with cacodylate and acetate ions present in the active site (see paper)
32% identity, 70% coverage: 14:173/230 of query aligns to 13:175/260 of 1qh3A
Sites not aligning to the query:
Q16775 Hydroxyacylglutathione hydrolase, mitochondrial; Glyoxalase II; Glx II; EC 3.1.2.6 from Homo sapiens (Human) (see paper)
32% identity, 71% coverage: 11:173/230 of query aligns to 58:223/308 of Q16775
Sites not aligning to the query:
2q42A Ensemble refinement of the protein crystal structure of glyoxalase ii from arabidopsis thaliana gene at2g31350 (see paper)
28% identity, 70% coverage: 13:173/230 of query aligns to 12:171/254 of 2q42A
Q9SID3 Hydroxyacylglutathione hydrolase 2, mitochondrial; Glyoxalase II; Glx II; EC 3.1.2.6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
28% identity, 70% coverage: 13:173/230 of query aligns to 82:241/324 of Q9SID3
>Synpcc7942_0937 FitnessBrowser__SynE:Synpcc7942_0937
MLFRQLFDRDTWTYTYLIADEASGEAALVDPVLEQCDRDLALLQDLGLTLKFCLETHLHA
DHITAAGRLRELTGCETVVPAGANATCADRFVVEGDRLQVGSIAITVIETRGHTDSHAAY
LIHQAELLTGDSLLIRGCGRTDFQSGDAGQLFDSVQRLFQLPDNTRVWPGHDYRGHTVST
IGEEKRLNRRFVGRDRQSFITFMNSLDLPDPQRIMEAVPANERCGHPATS
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory