Comparing Synpcc7942_0983 FitnessBrowser__SynE:Synpcc7942_0983 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 7 hits to proteins with known functional sites (download)
3ngjD Crystal structure of a putative deoxyribose-phosphate aldolase from entamoeba histolytica
41% identity, 91% coverage: 10:217/228 of query aligns to 10:219/222 of 3ngjD
Sites not aligning to the query:
Q4ZMV1 Deoxyribose-phosphate aldolase; DERA; 2-deoxy-D-ribose 5-phosphate aldolase; Phosphodeoxyriboaldolase; Deoxyriboaldolase; EC 4.1.2.4 from Pseudomonas syringae pv. syringae (strain B728a) (see paper)
39% identity, 91% coverage: 10:216/228 of query aligns to 9:217/226 of Q4ZMV1
1ub3A Crystal structure of tetrameric structure of aldolase from thermus thermophilus hb8 (see paper)
38% identity, 89% coverage: 9:212/228 of query aligns to 1:206/211 of 1ub3A
5el1A Crystal structure of deoxyribose-phosphate aldolase from escherichia coli (k58e-y96w mutant) after acetaldehyde treatment (see paper)
28% identity, 79% coverage: 17:196/228 of query aligns to 16:210/248 of 5el1A
Sites not aligning to the query:
5ekyA Crystal structure of deoxyribose-phosphate aldolase from escherichia coli (k58e-y96w mutant) (see paper)
28% identity, 79% coverage: 17:196/228 of query aligns to 16:210/248 of 5ekyA
Sites not aligning to the query:
Q9Y315 Deoxyribose-phosphate aldolase; DERA; 2-deoxy-D-ribose 5-phosphate aldolase; Phosphodeoxyriboaldolase; Deoxyriboaldolase; EC 4.1.2.4 from Homo sapiens (Human) (see paper)
27% identity, 67% coverage: 41:192/228 of query aligns to 97:261/318 of Q9Y315
3q2dA Optimization of the in silico designed kemp eliminase ke70 by computational design and directed evolution (see paper)
26% identity, 76% coverage: 24:196/228 of query aligns to 21:208/246 of 3q2dA
Sites not aligning to the query:
>Synpcc7942_0983 FitnessBrowser__SynE:Synpcc7942_0983
MAELSSDFDLAPYIEHSLLDPAATLEQIDQLCQEADRYHFAAVCLFPWVVRQAREWLNGR
SPRLCTVIDFPNGASTAASKVYAAQEAVENGAQELNVVVNLGWLRSDRADLVHQELAEIV
EATGVPIKAILEATRLNPSELEQLTDLCLDAGVTMLQTSTGWFGGATPALVQQLRQLTRN
RVGIHAAGGIRTWDQAAALVEAGAIRLGTSYGPMILQQRLAASTPAPA
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory