Comparing Synpcc7942_1847 FitnessBrowser__SynE:Synpcc7942_1847 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
5ktlA Dihydrodipicolinate synthase from the industrial and evolutionarily important cyanobacteria anabaena variabilis. (see paper)
62% identity, 97% coverage: 7:296/299 of query aligns to 5:294/295 of 5ktlA
5ud6C Crystal structure of dhdps from cyanidioschyzon merolae with lysine bound
56% identity, 98% coverage: 7:298/299 of query aligns to 4:299/299 of 5ud6C
P9WP25 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
46% identity, 95% coverage: 7:289/299 of query aligns to 12:291/300 of P9WP25
5j5dA Crystal structure of dihydrodipicolinate synthase from mycobacterium tuberculosis in complex with alpha-ketopimelic acid (see paper)
46% identity, 95% coverage: 7:289/299 of query aligns to 9:288/297 of 5j5dA
1xxxA Crystal structure of dihydrodipicolinate synthase (dapa, rv2753c) from mycobacterium tuberculosis (see paper)
46% identity, 95% coverage: 7:289/299 of query aligns to 8:287/296 of 1xxxA
3l21B The crystal structure of a dimeric mutant of dihydrodipicolinate synthase (dapa, rv2753c) from mycobacterium tuberculosis - dhdps- a204r
46% identity, 95% coverage: 7:289/299 of query aligns to 7:286/295 of 3l21B
4fhaA Structure of dihydrodipicolinate synthase from streptococcus pneumoniae,bound to pyruvate and lysine
41% identity, 97% coverage: 9:299/299 of query aligns to 9:297/307 of 4fhaA
Q9X1K9 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
42% identity, 97% coverage: 7:296/299 of query aligns to 2:293/294 of Q9X1K9
1o5kA Crystal structure of dihydrodipicolinate synthase (tm1521) from thermotoga maritima at 1.80 a resolution
41% identity, 97% coverage: 7:296/299 of query aligns to 3:294/295 of 1o5kA
4dxvA Crystal structure of dihydrodipicolinate synthase from acinetobacter baumannii complexed with mg and cl ions at 1.80 a resolution
41% identity, 96% coverage: 11:296/299 of query aligns to 6:290/291 of 4dxvA
3u8gA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with oxalic acid at 1.80 a resolution
41% identity, 96% coverage: 11:296/299 of query aligns to 6:290/291 of 3u8gA
3tdfA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 2-ketobutanoic acid at 1.99 a resolution
41% identity, 96% coverage: 11:296/299 of query aligns to 6:290/291 of 3tdfA
3tceA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 5-hydroxylysine at 2.6 a resolution
41% identity, 96% coverage: 11:296/299 of query aligns to 6:290/291 of 3tceA
3rk8A Crystal structure of the chloride inhibited dihydrodipicolinate synthase from acinetobacter baumannii complexed with pyruvate at 1.8 a resolution
41% identity, 96% coverage: 11:296/299 of query aligns to 6:290/291 of 3rk8A
3pueB Crystal structure of the complex of dhydrodipicolinate synthase from acinetobacter baumannii with lysine at 2.6a resolution
41% identity, 96% coverage: 11:296/299 of query aligns to 6:290/291 of 3pueB
5t25A Kinetic, spectral and structural characterization of the slow binding inhibitor acetopyruvate with dihydrodipicolinate synthase from escherichia coli.
40% identity, 98% coverage: 5:296/299 of query aligns to 1:292/293 of 5t25A
2atsA Dihydrodipicolinate synthase co-crystallised with (s)-lysine
40% identity, 97% coverage: 7:296/299 of query aligns to 2:291/292 of 2atsA
P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Escherichia coli (strain K12) (see 7 papers)
40% identity, 97% coverage: 7:296/299 of query aligns to 2:291/292 of P0A6L2
3i7sA Dihydrodipicolinate synthase mutant - k161a - with the substrate pyruvate bound in the active site. (see paper)
40% identity, 97% coverage: 7:296/299 of query aligns to 2:291/292 of 3i7sA
4pfmA Shewanella benthica dhdps with lysine and pyruvate
42% identity, 94% coverage: 11:291/299 of query aligns to 7:287/295 of 4pfmA
>Synpcc7942_1847 FitnessBrowser__SynE:Synpcc7942_1847
MPQPYPFGRVITAMITPFNAEGQVAYDIAQSLAVHLVEQGSDGLVICGTTGESPTLTWEE
ELQLFRAVKEAVGDRAAVIAGTGSNCTREAIAATQSAATLGLNGSLQVVPYYNKPPQEGL
YAHFRAIAEACPDLPLMLYNIPGRTGQSLQPETVARLASLPNVVAIKAASGNVEEVSALR
QLLPDSFAIYSGDDSLTLPMLAVGAQGVVSVASHLVGPQLQALIQAFEAGNVARAQQLHH
QLYPLFKALFLTTNPIPVRAAMELLGWSIGLPRLPLVPASAEIRQALASCLTELGLYTA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory