Comparing Synpcc7942_2046 FitnessBrowser__SynE:Synpcc7942_2046 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 13 hits to proteins with known functional sites (download)
P16048 Glycine cleavage system H protein, mitochondrial from Pisum sativum (Garden pea) (Lathyrus oleraceus) (see paper)
44% identity, 94% coverage: 7:127/129 of query aligns to 39:159/165 of P16048
1htpA Refined structures at 2 angstroms and 2.2 angstroms of the two forms of the h-protein, a lipoamide-containing protein of the glycine decarboxylase complex (see paper)
44% identity, 94% coverage: 7:127/129 of query aligns to 5:125/131 of 1htpA
Sites not aligning to the query:
1hpcB Refined structures at 2 angstroms and 2.2 angstroms of the two forms of the h-protein, a lipoamide-containing protein of the glycine decarboxylase (see paper)
44% identity, 94% coverage: 7:127/129 of query aligns to 5:125/131 of 1hpcB
1hpcA Refined structures at 2 angstroms and 2.2 angstroms of the two forms of the h-protein, a lipoamide-containing protein of the glycine decarboxylase (see paper)
44% identity, 94% coverage: 7:127/129 of query aligns to 5:125/131 of 1hpcA
1dxmA Reduced form of the h protein from glycine decarboxylase complex (see paper)
44% identity, 94% coverage: 7:127/129 of query aligns to 5:125/131 of 1dxmA
Sites not aligning to the query:
3ab9A Crystal structure of lipoylated e. Coli h-protein (reduced form) (see paper)
42% identity, 96% coverage: 6:129/129 of query aligns to 3:127/127 of 3ab9A
Q5SKW9 Glycine cleavage system H protein from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
42% identity, 96% coverage: 6:129/129 of query aligns to 4:127/128 of Q5SKW9
Q9HDV9 Putative glycine cleavage system H protein, mitochondrial; Glycine decarboxylase complex subunit H from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
41% identity, 86% coverage: 2:112/129 of query aligns to 38:147/169 of Q9HDV9
P23434 Glycine cleavage system H protein, mitochondrial; Lipoic acid-containing protein from Homo sapiens (Human) (see 4 papers)
38% identity, 91% coverage: 10:127/129 of query aligns to 52:169/173 of P23434
Sites not aligning to the query:
P20821 Glycine cleavage system H protein, mitochondrial; Lipoic acid-containing protein from Bos taurus (Bovine) (see 3 papers)
36% identity, 91% coverage: 10:127/129 of query aligns to 52:169/173 of P20821
Sites not aligning to the query:
P11183 Glycine cleavage system H protein, mitochondrial; Lipoic acid-containing protein from Gallus gallus (Chicken) (see paper)
34% identity, 91% coverage: 10:127/129 of query aligns to 43:160/164 of P11183
Sites not aligning to the query:
A0A0H3JT43 Glycine cleavage system H-like protein; GcvH-L from Staphylococcus aureus (strain Mu50 / ATCC 700699) (see paper)
30% identity, 75% coverage: 9:105/129 of query aligns to 1:96/110 of A0A0H3JT43
P0DN69 Glycine cleavage system H-like protein; GcvH-L from Streptococcus pyogenes serotype M5 (strain Manfredo) (see paper)
33% identity, 53% coverage: 35:103/129 of query aligns to 27:94/110 of P0DN69
Sites not aligning to the query:
>Synpcc7942_2046 FitnessBrowser__SynE:Synpcc7942_2046
MALIYPDNLRYFDSHEYVRLDGDIAVIGISAYAIDQLGDIVFLELPEVGSTIAIGASFGT
VESVKAVEEVYAPVTGEIIERNEAALEAPEILNSDPYEQGWLLKVQLTGKPDLSDSYDAA
QYQALVEGQ
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory