Comparing WP_002724637.1 NCBI__GCF_000015985.1:WP_002724637.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
3e0iA Cu2+ substituted aquifex aeolicus kdo8ps in complex with pep (see paper)
52% identity, 91% coverage: 23:274/278 of query aligns to 5:256/263 of 3e0iA
2a21A Aquifex aeolicus kdo8ps in complex with pep, po4, and zn2+ (see paper)
52% identity, 91% coverage: 23:274/278 of query aligns to 5:256/263 of 2a21A
1jcyA Aquifex aeolicus kdo8p synthase in complex with r5p, pep and cadmium (see paper)
52% identity, 91% coverage: 23:274/278 of query aligns to 5:256/263 of 1jcyA
1fwwA Aquifex aeolicus kdo8p synthase in complex with pep, a5p and cadmium (see paper)
52% identity, 91% coverage: 23:274/278 of query aligns to 5:256/263 of 1fwwA
1fwtA Aquifex aeolicus kdo8p synthase in complex with pep, e4p and cadmium (see paper)
52% identity, 91% coverage: 23:274/278 of query aligns to 5:256/263 of 1fwtA
2nx3D Structural and mechanistic changes along an engineered path from metallo to non-metallo kdo8p synthase (see paper)
52% identity, 91% coverage: 23:274/278 of query aligns to 4:255/262 of 2nx3D
2nx1A Structural and mechanistic changes along an engineered path from metallo to non-metallo kdo8p synthase (see paper)
51% identity, 91% coverage: 23:274/278 of query aligns to 5:256/263 of 2nx1A
3e12A Cu2+ substituted aquifex aeolicus kdo8ps in complex with kdo8p (see paper)
50% identity, 91% coverage: 23:274/278 of query aligns to 5:251/258 of 3e12A
1pckA Aquifex aeolicus kdo8ps in complex with z-methyl-pep (see paper)
52% identity, 87% coverage: 23:264/278 of query aligns to 5:241/258 of 1pckA
1pe1A Aquifex aeolicus kdo8ps in complex with cadmium and 2-pga (see paper)
50% identity, 91% coverage: 23:274/278 of query aligns to 6:251/258 of 1pe1A
1pcwA Aquifex aeolicus kdo8ps in complex with cadmium and app, a bisubstrate inhibitor (see paper)
52% identity, 87% coverage: 23:264/278 of query aligns to 5:240/257 of 1pcwA
3undB Substrate-bound crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from burkholderia pseudomallei (see paper)
47% identity, 95% coverage: 13:277/278 of query aligns to 12:278/284 of 3undB
1jcxA Aquifex aeolicus kdo8p synthase in complex with api and cadmium (see paper)
51% identity, 87% coverage: 23:264/278 of query aligns to 5:238/255 of 1jcxA
1g7vA Crystal structures of kdo8p synthase in its binary complexes with the mechanism-based inhibitor (see paper)
43% identity, 97% coverage: 7:277/278 of query aligns to 5:277/284 of 1g7vA
1g7uA Crystal structures of kdo8p synthase in its binary complex with substrate phosphoenol pyruvate (see paper)
43% identity, 97% coverage: 7:277/278 of query aligns to 5:277/284 of 1g7uA
3fyoD Crystal structure of the triple mutant (n23c/d247e/p249a) of 3-deoxy- d-manno-octulosonate 8-phosphate synthase (kdo8ps) from neisseria meningitidis (see paper)
44% identity, 97% coverage: 8:276/278 of query aligns to 3:257/261 of 3fyoD
4z1dA Structure of pep and zinc bound kdo8ps from h.Pylori (see paper)
48% identity, 91% coverage: 22:273/278 of query aligns to 3:255/256 of 4z1dA
1x6uA Kdo8p synthase in it's binary complex with the product kdo8p (see paper)
42% identity, 97% coverage: 7:277/278 of query aligns to 5:265/272 of 1x6uA
1phwA Crystal structure of kdo8p synthase in its binary complex with substrate analog 1-deoxy-a5p (see paper)
42% identity, 97% coverage: 7:277/278 of query aligns to 5:265/272 of 1phwA
1phqA Crystal structure of kdo8p synthase in its binary complex with substrate analog e-fpep
42% identity, 97% coverage: 7:277/278 of query aligns to 5:265/272 of 1phqA
>WP_002724637.1 NCBI__GCF_000015985.1:WP_002724637.1
MTETPTIVTIGDIAIGGGHPIALITGPCQLESLDHARMMAERIAEACAPTGTKFIFKASY
DKANRSSLSTARGLGMEKGLEILGRIREEFGVPVLTDVHEPGHCATAAEVCDVLQIPAFL
CRQTDLLLAAGETGRAVNVKKGQFLAPWDMKNVADKVASTGNRRILLCERGTSFGYNTLV
TDFRGLPTMAATGWPVVFDATHSVQQPGGLGGSSGGQREFAPVLARAACAVGVSALFIET
HEDPDRAPSDGPNMIPVDRMGRLIADLCAFDALAKSLA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory