SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_003942105.1 NCBI__GCF_002893965.1:WP_003942105.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 2 hits to proteins with known functional sites (download)

4ymwC Crystal structure of an amino acid abc transporter with histidines (see paper)
33% identity, 77% coverage: 6:178/226 of query aligns to 10:170/214 of 4ymwC

query
sites
4ymwC
K
 
K
Y
 
Y
G
 
T
D
 
P
Q
 
L
L
 
F
L
 
I
E
 
S
A
 
G
F
 
L
W
 
I
T
 
M
T
 
T
I
 
L
Q
 
K
L
 
L
T
 
T
F
 
F
F
 
L
S
 
A
A
 
V
I
 
T
G
 
I
A
 
G
V
 
V
I
 
L
I
 
M
G
 
G
V
 
L
L
 
F
I
 
I
A
 
A
A
 
L
M
 
M
R
 
K
V
 
M
S
 
S
P
 
S
V
 
I
P
 
K
V
 
P
A
 
I
R
 
K
F
 
L
L
 
V
G
 
A
A
 
S
A
 
S
Y
 
Y
V
 
I
T
 
E
V
 
V
F
 
I
R
 
R
N
 
G
T
 
T
P
 
P
L
 
L
T
 
L
L
 
V
I
 
Q
L
 
L
L
 
L
F
 
L
C
 
I
L
 
Y
F
 
N
G
 
G
L
 
L
S
 
M
Q
 
Q
T
 
-
L
 
F
G
 
G
V
 
M
N
 
N
L
 
I
A
 
P
K
 
A
S
 
-
D
 
-
S
 
-
P
 
-
T
 
-
F
 
-
L
 
-
V
 
-
D
 
-
N
 
-
N
 
-
F
 
F
R
 
T
L
 
A
A
 
G
V
 
V
L
 
S
G
 
A
L
 
L
S
 
A
V
 
I
Y
x
N
T
 
S
A
 
S
A
 
A
F
x
Y
V
 
V
C
 
A
E
 
E
S
 
I
L
 
I
R
 
R
S
 
A
G
 
G
I
 
I
N
 
Q
T
 
A
V
 
V
P
 
D
V
 
P
G
 
G
Q
 
Q
A
 
N
E
 
E
A
 
A
G
 
A
R
 
R
S
 
S
L
 
L
G
 
G
L
 
M
S
 
T
F
 
H
A
 
A
Q
 
M
N
 
A
L
 
M
R
 
R
L
 
Y
I
 
V
V
 
I
L
 
I
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P
Q
 
Q
A
 
A
F
 
I
R
 
K
A
 
N
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I
T
 
L
A
 
P
P
 
A
L
 
L
G
 
G
S
 
N
V
x
E
L
 
F
I
 
I
A
 
V
L
 
M
T
 
L
K
 
K
N
x
E
S
 
S
T
 
A
I
 
I
A
 
V
A
 
S
V
 
V
I
 
I
G
 
G
V
 
F
S
 
A
E
 
D

4ymtC Crystal structure of an amino acid abc transporter complex with arginines (see paper)
33% identity, 77% coverage: 6:178/226 of query aligns to 10:170/215 of 4ymtC

query
sites
4ymtC
K
 
K
Y
 
Y
G
 
T
D
 
P
Q
 
L
L
 
F
L
 
I
E
 
S
A
 
G
F
 
L
W
 
I
T
 
M
T
 
T
I
 
L
Q
 
K
L
 
L
T
 
T
F
 
F
F
 
L
S
 
A
A
 
V
I
 
T
G
 
I
A
 
G
V
 
V
I
 
L
I
 
M
G
 
G
V
 
L
L
 
F
I
 
I
A
 
A
A
 
L
M
 
M
R
 
K
V
 
M
S
 
S
P
 
S
V
 
I
P
 
K
V
 
P
A
 
I
R
 
K
F
 
L
L
 
V
G
 
A
A
 
S
A
 
S
Y
 
Y
V
 
I
T
 
E
V
 
V
F
 
I
R
 
R
N
 
G
T
 
T
P
|
P
L
|
L
T
 
L
L
 
V
I
 
Q
L
 
L
L
 
L
F
 
L
C
 
I
L
 
Y
F
 
N
G
 
G
L
 
L
S
 
M
Q
 
Q
T
 
-
L
 
F
G
 
G
V
 
M
N
 
N
L
 
I
A
 
P
K
 
A
S
 
-
D
 
-
S
 
-
P
 
-
T
 
-
F
 
-
L
 
-
V
 
-
D
 
-
N
 
-
N
 
-
F
 
F
R
 
T
L
 
A
A
 
G
V
 
V
L
 
S
G
 
A
L
 
L
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A
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I
Y
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S
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A
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Y
V
 
V
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A
E
 
E
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A
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G
I
 
I
N
 
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A
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G
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E
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A
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L
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G
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M
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H
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A
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M
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A
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R
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Y
I
 
V
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I
L
 
I
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P
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Q
A
 
A
F
 
I
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K
A
 
N
V
 
I
T
 
L
A
 
P
P
 
A
L
 
L
G
 
G
S
 
N
V
x
E
L
 
F
I
 
I
A
 
V
L
x
M
T
 
L
K
|
K
N
x
E
S
 
S
T
 
A
I
 
I
A
 
V
A
 
S
V
 
V
I
 
I
G
 
G
V
 
F
S
 
A
E
 
D

Query Sequence

>WP_003942105.1 NCBI__GCF_002893965.1:WP_003942105.1
MNLLSKYGDQLLEAFWTTIQLTFFSAIGAVIIGVLIAAMRVSPVPVARFLGAAYVTVFRN
TPLTLILLFCLFGLSQTLGVNLAKSDSPTFLVDNNFRLAVLGLSVYTAAFVCESLRSGIN
TVPVGQAEAGRSLGLSFAQNLRLIVLPQAFRAVTAPLGSVLIALTKNSTIAAVIGVSEAS
ALMKKMIENEAAIFVVGGIFAVGFVILTLPMGLIFGKLSKRFEVSR

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory