Comparing WP_004045055.1 NCBI__GCF_000337315.1:WP_004045055.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
3vpdA Lysx from thermus thermophilus complexed with amp-pnp (see paper)
44% identity, 96% coverage: 3:282/291 of query aligns to 2:281/281 of 3vpdA
5k2mI Bifunctional lysx/argx from thermococcus kodakarensis with lysw-gamma- aaa (see paper)
38% identity, 95% coverage: 1:275/291 of query aligns to 1:266/273 of 5k2mI
5k2mG Bifunctional lysx/argx from thermococcus kodakarensis with lysw-gamma- aaa (see paper)
38% identity, 95% coverage: 1:275/291 of query aligns to 1:266/273 of 5k2mG
1uc9A Crystal structure of a lysine biosynthesis enzyme, lysx, from thermus thermophilus hb8 (see paper)
37% identity, 94% coverage: 3:275/291 of query aligns to 2:250/256 of 1uc9A
3vpbB Argx from sulfolobus tokodaii complexed with lysw/glu/adp/mg/zn/sulfate (see paper)
29% identity, 95% coverage: 1:277/291 of query aligns to 1:277/282 of 3vpbB
Q970U6 Glutamate--LysW ligase ArgX; EC 6.3.2.- from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
29% identity, 95% coverage: 1:277/291 of query aligns to 1:277/282 of Q970U6
Q4JAP9 Alpha-aminoadipate--LysW ligase LysX; AAA--LysW ligase LysX; EC 6.3.2.43 from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) (see paper)
31% identity, 86% coverage: 10:258/291 of query aligns to 1:252/276 of Q4JAP9
Sites not aligning to the query:
7qyrD Crystal structure of rimk from pseudomonas aeruginosa pao1 (see paper)
25% identity, 93% coverage: 6:277/291 of query aligns to 12:287/293 of 7qyrD
Sites not aligning to the query:
4iwxA Rimk structure at 2.85a (see paper)
24% identity, 95% coverage: 4:280/291 of query aligns to 12:292/294 of 4iwxA
5zctH The crystal structure of the poly-alpha-l-glutamate peptides synthetase rimk at 2.05 angstrom resolution. (see paper)
24% identity, 95% coverage: 4:280/291 of query aligns to 10:290/292 of 5zctH
5zctA The crystal structure of the poly-alpha-l-glutamate peptides synthetase rimk at 2.05 angstrom resolution. (see paper)
24% identity, 95% coverage: 4:280/291 of query aligns to 10:290/292 of 5zctA
7lgmA Cyanophycin synthetase from a. Baylyi dsm587 with atp (see paper)
31% identity, 41% coverage: 80:199/291 of query aligns to 208:322/719 of 7lgmA
Sites not aligning to the query:
7waeB Trichodesmium erythraeum cyanophycin synthetase 1 (tecpha1) with atpgammas, 4x(beta-asp-arg), and aspartate (see paper)
30% identity, 47% coverage: 68:204/291 of query aligns to 187:332/877 of 7waeB
Sites not aligning to the query:
7waeD Trichodesmium erythraeum cyanophycin synthetase 1 (tecpha1) with atpgammas, 4x(beta-asp-arg), and aspartate (see paper)
30% identity, 47% coverage: 68:204/291 of query aligns to 187:332/724 of 7waeD
Sites not aligning to the query:
8fxiD Cryo-em structure of stanieria sp. Cpha2 in complex with adpcp and 4x(beta-asp-arg) (see paper)
32% identity, 41% coverage: 78:195/291 of query aligns to 199:316/630 of 8fxiD
Sites not aligning to the query:
8fxiC Cryo-em structure of stanieria sp. Cpha2 in complex with adpcp and 4x(beta-asp-arg) (see paper)
32% identity, 41% coverage: 78:195/291 of query aligns to 199:316/630 of 8fxiC
Sites not aligning to the query:
O58056 Formate-dependent phosphoribosylglycinamide formyltransferase; 5'-phosphoribosylglycinamide transformylase 2; Formate-dependent GAR transformylase; GAR transformylase 2; GART 2; Non-folate glycinamide ribonucleotide transformylase; Phosphoribosylglycinamide formyltransferase 2; EC 6.3.1.21 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
26% identity, 54% coverage: 97:252/291 of query aligns to 126:290/430 of O58056
Sites not aligning to the query:
7txuA Cyanophycin synthetase 1 from synechocystis sp. Utex2470 with atp and 16x(asp-arg)
33% identity, 40% coverage: 85:199/291 of query aligns to 215:324/869 of 7txuA
Sites not aligning to the query:
7lgjA Cyanophycin synthetase 1 from synechocystis sp. Utex2470 with adpcp and 8x(asp-arg)-nh2 (see paper)
33% identity, 40% coverage: 85:199/291 of query aligns to 215:324/869 of 7lgjA
Sites not aligning to the query:
1kjiA Crystal structure of glycinamide ribonucleotide transformylase in complex with mg-amppcp (see paper)
29% identity, 63% coverage: 70:252/291 of query aligns to 93:278/389 of 1kjiA
Sites not aligning to the query:
>WP_004045055.1 NCBI__GCF_000337315.1:WP_004045055.1
MHVGLLYSRIRRDEKLLLNELRDRGHEVTKIDVRKEQFDLTEPPESFDGLDVVVDRCLAT
SRSIYITRFLKSYGIPVVNSHETADICADKAKNSLALADAGVPTPNTKVAFTVDSAMDIV
EEFGYPCVLKPVVGSWGRLMAKIDSESAAEAILEHKSTLGNYEHKVFYIQEFVEKPGRDI
RVLATDGEPVAAMVRSSDHWLTNAAKGASVDEFELDDRAKELVKQASDAVGGGLLGVDLM
ETGDDYTVHEVNHTVEFKALNDAVEADVPATVVDWLEAKADGAQSLAEVSA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory