Comparing WP_004307344.1 NCBI__GCF_000310185.1:WP_004307344.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 4 hits to proteins with known functional sites (download)
1ox4B Towards understanding the mechanism of the complex cyclization reaction catalyzed by imidazole glycerophosphate synthase (see paper)
35% identity, 100% coverage: 1:211/212 of query aligns to 4:215/538 of 1ox4B
Sites not aligning to the query:
1ox5A Towards understanding the mechanism of the complex cyclization reaction catalyzed by imidazole glycerophosphate synthase (see paper)
35% identity, 100% coverage: 1:211/212 of query aligns to 4:215/532 of 1ox5A
Sites not aligning to the query:
P33734 Imidazole glycerol phosphate synthase hisHF; IGP synthase; IGPS; ImGP synthase; EC 4.3.2.10; EC 3.5.1.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
35% identity, 100% coverage: 1:211/212 of query aligns to 1:212/552 of P33734
Sites not aligning to the query:
7ac8B Molecular basis for the unique allosteric activation mechanism of the heterodimeric imidazole glycerol phosphate synthase complex. (see paper)
32% identity, 97% coverage: 4:208/212 of query aligns to 5:196/202 of 7ac8B
>WP_004307344.1 NCBI__GCF_000310185.1:WP_004307344.1
MTSVAIIDYGMGNLRSVAKAIEHVAPGHEVFVTSDPARVAAAERVVFPGQGAMPDCMREL
DARGLRPAVRAAAAEKPFLGICIGQQMLFQRSAEGDVPGLGILSGEVVRFPETGMFAADG
SRLKVPHMGWNEVRQCGPHPMWDGIPDGERFYFVHSYFVVPAEASLTAAETDYGVRFTSA
VARANIFAAQFHPEKSAAAGLRLLANFIRWQP
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory